Invokana® Tablets for Type 2 Diabetes

Invokana® is the brand name for canagliflozin, an oral SGLT2 inhibitor used for adults with type 2 diabetes. This page explains what it is, how it works, and how to use it safely. We offer Canadian pricing with US delivery from Canada, including options if paying without insurance.

CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order.

What Invokana® Is and How It Works

Invokana is an SGLT2 inhibitor. It helps the kidneys remove extra glucose through the urine, which lowers blood sugar. It also tends to reduce body weight and lower systolic blood pressure modestly.

Invokana is approved to improve glycemic control in adults with type 2 diabetes, along with diet and exercise. It also has indications to reduce certain risks in adults with type 2 diabetes and diabetic kidney disease with albuminuria. Ask your clinician how these benefits apply to your situation.

At CanadianInsulin, orders are processed from Canada and ship to the US. You can buy Invokana online with a valid prescription and access Canadian pricing.

Who Invokana® Is For

Invokana is for adults with type 2 diabetes who need additional blood sugar control. It may be considered when metformin alone is not enough, or when a clinician prefers an SGLT2 inhibitor because of heart or kidney considerations. It is not for type 1 diabetes or for treating diabetic ketoacidosis.

People with very low kidney function, those on dialysis, or with a history of serious allergic reaction to canagliflozin should not use it. Caution is advised in people with volume depletion, frequent genital infections, peripheral vascular disease, or a history of foot ulcers or amputations. For broader therapy options, see our category for Type 2 Diabetes.

Dosage and Usage

Standard dosing is once daily, before the first meal of the day. This timing helps limit post-meal glucose rises. Swallow tablets whole with water.

• Typical starting dose: 100 mg once daily.
• Possible increase: 300 mg once daily if tolerated and kidney function allows.
• Renal considerations: dosing and eligibility depend on eGFR. Use is limited or not recommended at low eGFR levels. Follow the official label and your prescriber’s guidance.

Monitor blood glucose as directed. Hypoglycemia can occur when Invokana is combined with insulin or a sulfonylurea. Clinicians may adjust companion therapy to reduce that risk. For a deeper overview, see Invokana Dosage.

Strengths and Forms

Invokana comes as film-coated oral tablets. Common strengths are:

• 100 mg tablet
• 300 mg tablet

Packaging and availability may vary by pharmacy and country. Specific options can change over time.

Missed Dose and Timing

If a once-daily dose is missed, take it as soon as remembered the same day. If it is almost time for the next scheduled dose, skip the missed dose. Do not take two doses at once. Resume the regular schedule the next day.

Storage and Travel Basics

Store tablets at room temperature in the original container. Protect from moisture and excessive heat. Keep out of reach of children and pets.

When traveling, keep your medicine in a carry-on bag with the pharmacy label. You can store your tablets without special cooling. Our checkout uses encrypted processing for your security.

Benefits

• Once-daily tablet for type 2 diabetes.
• Lowers A1C by increasing urinary glucose excretion.
• May support modest weight reduction and lower blood pressure.
• Evidence for certain kidney and cardiovascular benefits in appropriate patients.
• Oral option when an injectable is not desired.

These benefits align with the SGLT2 inhibitor class effect. Individual results and suitability vary. Explore additional support options in Blood Sugar Control.

Side Effects and Safety

• Common: increased urination, thirst, genital yeast infections, urinary tract infections.
• Other: dizziness, hypotension, constipation, nausea, dehydration.
• Metabolic: elevated potassium can occur in at-risk patients.

Serious but less common risks include ketoacidosis, severe urinary infections including urosepsis and pyelonephritis, acute kidney injury, Fournier’s gangrene, fractures, and lower limb amputation risk. Stop the drug and seek urgent care if symptoms of ketoacidosis occur, such as nausea, vomiting, abdominal pain, or unusual fatigue, even if blood glucose is not very high. Hypoglycemia risk increases when used with insulin or a sulfonylurea.

Drug Interactions and Cautions

• Diuretics: higher risk of dehydration and low blood pressure.
• RAAS blockers: monitor kidney function and potassium as clinically indicated.
• Digoxin: canagliflozin may raise digoxin levels; monitoring may be needed.
• UGT enzyme inducers like rifampin, phenytoin, or carbamazepine may reduce canagliflozin exposure.
• Alcohol excess increases risk of dehydration and ketoacidosis.

Report all prescription drugs, OTC medicines, and supplements to your clinician. Follow the approved label for comprehensive safety information.

What to Expect Over Time

Blood glucose often improves within days of starting therapy. A1C changes reflect over weeks to months of consistent use. Some people notice modest weight and blood pressure reductions. Kidney and cardiovascular outcome benefits accrue over longer periods in appropriate patients.

Regular follow-up helps track A1C, kidney function, and side effects. For background on how SGLT2 agents work, review our explainer on Invokana Drug Class.

Compare With Alternatives

Other SGLT2 inhibitors include dapagliflozin and empagliflozin. These have similar glucose effects, with label differences for kidney and heart indications. Consider prior history, kidney function, coexisting conditions, and cost when comparing choices.

Two options often discussed are Farxiga® Dapagliflozin and Jardiance® 10 25 Mg. Your prescriber can help select the agent that aligns with your goals and medical history.

Pricing and Access

Access Canadian pricing and US delivery from Canada when you order Invokana tablets online. Compare the Invokana price and see potential cash-pay savings before checkout. You can review current cost, available strengths, and quantities on the product page.

If your clinician suggests a different form or dose, you can request those during checkout. A valid prescription is required for shipment. We offer prompt US shipping after prescription verification.

Availability and Substitutions

Stock and packaging can vary over time. If a specific strength is unavailable, a prescriber may recommend a different strength or an alternative SGLT2 inhibitor. Combination products that include canagliflozin and metformin may also be discussed.

One example is Invokamet®, which combines canagliflozin with metformin. Substitutions are guided by your prescriber and your medical needs.

Patient Suitability and Cost Saving Tips

• Good candidates: adults with type 2 diabetes who need additional A1C reduction, particularly with kidney or cardiovascular risk factors considered.
• Avoid or use caution: severe renal impairment, dialysis, frequent genital infections, or high amputation risk.
• If taking insulin or a sulfonylurea, monitor for hypoglycemia.
• Maintain hydration, foot care, and sick-day plans to reduce complications.

Cost-saving ideas include choosing a multi-month supply, setting refill reminders, and comparing tablet strengths if equivalent daily doses reduce cost per tablet. Some patients discuss generic alternatives or different SGLT2 inhibitors if pricing changes.

Questions to Ask Your Clinician

• Is Invokana appropriate for my kidney function and A1C goals?
• Should I start at 100 mg or consider 300 mg later?
• How does Invokana fit with my metformin or insulin plan?
• What signs of dehydration or ketoacidosis should I watch for?
• Do my other medicines interact with canagliflozin?
• What lab tests should we monitor and how often?
• Would an SGLT2 alternative better match my heart or kidney profile?

Authoritative Sources

• Manufacturer: Invokana
• DailyMed: Canagliflozin Labeling
• Health Canada Drug Product Database

Availability and Ordering

Ready to proceed? You can place your order online for US delivery from Canada after we confirm your prescription. Always follow your prescriber’s advice and the approved label.

This information is educational and not a substitute for professional medical advice. Consult your clinician for individualized guidance.