Kerendia® for Chronic Kidney Disease in Type 2 Diabetes

Kerendia® is finerenone, a nonsteroidal mineralocorticoid receptor antagonist. It helps reduce the risk of kidney and heart complications in adults with chronic kidney disease linked to type 2 diabetes. CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order. This page explains how Kerendia works, who it is for, and how to use it. You can order from Canada with US delivery. Many patients compare Kerendia cost and Kerendia price online, even without insurance, to find Canadian pricing that ships to the US.

Kerendia is often used alongside standard care for Chronic Kidney Disease. The information below summarizes widely published guidance, but always follow your clinician’s directions and the official label.

What Kerendia® Is and How It Works

Kerendia® contains finerenone. It is a selective, nonsteroidal blocker of the mineralocorticoid receptor. Overactivation of this receptor can drive kidney inflammation and fibrosis. By blocking the receptor, Kerendia helps slow kidney damage and lowers the risk of heart outcomes in adults with chronic kidney disease associated with type 2 diabetes.

Kerendia is not an insulin or a blood sugar medicine. It is not a diuretic. It is commonly used with background therapy such as an ACE inhibitor or an ARB when tolerated. Your care team will monitor potassium and kidney function during treatment.

Who Kerendia® Is For

Kerendia is indicated for adults with chronic kidney disease tied to type 2 diabetes. It is used to reduce the risk of sustained eGFR decline, kidney failure, cardiovascular death, nonfatal heart attack, and hospitalization for heart failure.

Do not use Kerendia if you have known hypersensitivity to finerenone. Do not start if your potassium is elevated above typical safety thresholds or if you use strong CYP3A4 inhibitors. Use is not recommended in severe liver impairment. Your clinician will assess your baseline eGFR and potassium before starting.

Dosage and Usage

Kerendia is taken by mouth once daily, with or without food. Swallow tablets whole with water. The initial dose depends on kidney function at baseline. Many adults start at 10 mg or 20 mg once daily, guided by eGFR and serum potassium. The maximum recommended dose is 20 mg once daily.

Potassium and kidney function are rechecked about four weeks after starting or changing dose, and periodically after that. Your clinician may adjust, hold, or restart Kerendia based on potassium results and clinical status. Always follow the dosing schedule on your prescription label.

Strengths and Forms

Kerendia tablets are commonly available in:

• 10 mg tablets
• 20 mg tablets

Availability can vary by pharmacy and package size. Strengths listed reflect widely published presentations.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose. Do not take two doses at the same time. Try to take Kerendia at a consistent time each day.

Storage and Travel Basics

Store Kerendia tablets at room temperature and keep the bottle closed tightly. Protect from moisture and excess heat. Keep out of reach of children and pets. When traveling, carry your medication in the original labeled container. Pack enough tablets for your trip and a few extra days.

Benefits

Kerendia helps protect kidney function in adults with chronic kidney disease from type 2 diabetes. It lowers the risk of progressive eGFR decline, kidney failure, and major heart events. Once-daily dosing supports adherence. It can be used alongside standard glucose and blood pressure therapies when appropriate.

Side Effects and Safety

• High potassium
• Low blood pressure
• Dizziness or lightheadedness
• Changes in kidney function tests
• Fatigue

Serious risks include hyperkalemia that may require treatment or temporary drug interruption. Low blood pressure may occur, especially if you are on multiple blood pressure medicines. Your care team will monitor potassium and kidney function at baseline and during therapy. Call your clinician if you have muscle weakness, palpitations, or symptoms of severe dizziness or fainting.

Drug Interactions and Cautions

Kerendia is metabolized by CYP3A4. Avoid strong CYP3A4 inhibitors (for example, certain antifungals or antibiotics) and strong inducers. Grapefruit or grapefruit juice can increase exposure and should be avoided. Combining Kerendia with other medicines that raise potassium may increase the risk of hyperkalemia. These include potassium supplements, salt substitutes containing potassium, and potassium-sparing agents.

Kerendia is typically added to an ACE inhibitor or an ARB when tolerated, not used with both at the same time. Your clinician will individualize your regimen. If potassium rises, your clinician may pause Kerendia or adjust other therapies. Potassium binders, such as Veltassa® Sachet, are sometimes used to manage high potassium when clinically appropriate. Background blood pressure agents like Captopril may be part of overall care when indicated.

Tell your clinician about all medicines, vitamins, and herbal supplements. Do not change or stop medications without medical advice.

What to Expect Over Time

You should not feel an immediate effect from Kerendia. Its benefits relate to long-term protection of kidney and heart outcomes. Regular labs guide safe use and dosing. Over months, your care team watches trends in eGFR and potassium. Blood sugar control, blood pressure management, and lifestyle support remain important alongside Kerendia.

To learn more about kidney protection, you may find these articles helpful: Kerendia Uses and Diabetes And Kidney Damage.

Compare With Alternatives

Guidelines often recommend an SGLT2 inhibitor for adults with type 2 diabetes and chronic kidney disease, when appropriate. Kerendia works differently and may be used in addition to these agents. Alternatives you can consider with your clinician include Farxiga® and Invokamet®. Choice depends on your medical history, current labs, and other medications.

Pricing and Access

Compare Kerendia cost and Kerendia price with Canadian pricing that ships to the US. You can check today’s price, see available strengths, and start an order when ready. US delivery from Canada is available after prescription verification. Secure checkout is supported.

To save on ongoing therapy, many patients review multi-month supply options. Your prescription is required and verified.

Availability and Substitutions

If Kerendia is temporarily unavailable, your prescriber may recommend a suitable alternative based on your diagnosis and labs. Do not switch medicines without guidance. Pharmacy availability can vary by strength and package size.

Patient Suitability and Cost Saving Tips

Kerendia may suit adults with chronic kidney disease from type 2 diabetes who need kidney and heart risk reduction beyond standard care. It is not right for people with very high potassium, those on contraindicated medicines, or severe liver impairment. Your clinician will review labs and medications before starting.

• Ask about 60- or 90-day supplies to reduce per-fill costs.
• Set refill reminders to avoid missed doses.
• Keep lab appointments for potassium and kidney checks.
• Maintain blood pressure and glucose control as advised.
• Discuss diet changes that limit excess potassium if needed.

Questions to Ask Your Clinician

• Is Kerendia appropriate for my stage of kidney disease?
• How should we monitor potassium and eGFR after I start?
• Should I change any ACE inhibitor, ARB, or diuretic doses?
• Are there foods or supplements I should avoid?
• What signs of high potassium should I watch for?
• Could an SGLT2 inhibitor also help in my case?
• How long should I stay on Kerendia if labs are stable?

Authoritative Sources

• FDA DailyMed
• Bayer Prescribing Info
• Health Canada DPD

Ready to start? Place your Kerendia request with US delivery from Canada. This information is educational and does not replace your clinician’s advice.