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Fenofibrate Tablets for High Triglycerides
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Fenofibrate is a lipid-modifying medicine used to reduce very high triglycerides and improve certain cholesterol measures. This page explains how it works, who it may suit, and how to use it safely. US shipping from Canada is available, with options that may help if you pay without insurance.
What Fenofibrate Is and How It Works
This medicine belongs to the fibrate class. It activates peroxisome proliferator-activated receptor alpha (PPAR-α), which helps lower triglycerides and raise HDL cholesterol. It can also reduce some atherogenic particles in mixed dyslipidemia. Treatment is used along with a diet low in saturated fat and a lifestyle plan tailored to lipid control.
Therapy addresses elevated triglycerides that may increase pancreatitis risk and contribute to cardiovascular risk. It can be considered when diet and exercise alone are not enough, or alongside statins in select patients where benefits outweigh risks. For information about triglyceride-focused care, see High Triglycerides. In some markets, related products appear under names such as lipanthyl 145. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.
Who It’s For
This treatment is indicated for adults with severe hypertriglyceridemia and for primary hypercholesterolemia or mixed dyslipidemia, when used with diet. It is not a first choice for preventing heart disease but may be used as part of a broader risk-reduction plan. Discuss suitability if you have diabetes, metabolic syndrome, or a family history of premature cardiovascular disease. Common queries include fenofibrate 145 mg uses, which generally align with these label indications.
Do not use this medicine if you have active liver disease, severe kidney impairment, or pre-existing gallbladder disease. People with a history of pancreatitis unrelated to hypertriglyceridemia should avoid it. Use in pregnancy or during breastfeeding is generally not recommended unless the potential benefit justifies the potential risk. For broader lipid topics, review High Cholesterol.
Dosage and Usage
Tablets are typically taken once daily as directed. Some formulations can be taken without regard to meals; others may require administration with food. Follow the specific instructions provided with your product and your clinician’s guidance. When switching formulations, dosing may not be interchangeable due to differences in bioavailability.
Take the medicine at the same time each day to support adherence. Swallow tablets whole with water; do not crush or chew unless your pharmacist confirms it is appropriate for your specific product. Your clinician may order periodic blood tests to monitor lipids, liver enzymes, and kidney function. Label-based dosing adjustments may be needed for renal impairment. Patients often search for fenofibrate dosage 145 mg; follow your prescriber’s instructions and the official label rather than general summaries.
Strengths and Forms
Oral presentations include tablets and capsules, with strengths that vary by manufacturer and formulation. Commonly published tablet strengths include a lower and a higher dose; nanocrystal formulations are designed for improved absorption. Micronized capsules exist at several strengths in certain markets. Availability may differ by pharmacy, province, and manufacturer.
Some labels allow dosing without regard to meals due to formulation technology, while others must be taken with food. Always check your product’s leaflet to confirm proper administration. If you need a class alternative within cardiovascular care, browse related items under Cardiovascular.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to the time for the next dose. Skip the missed dose if it is almost time for the next one. Do not double up to make up for a missed tablet. Patients sometimes refer to fenofibrate 145 mg tablet when discussing schedule, but timing instructions are the same regardless of formulation specifics.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from excess heat and light. Keep them in the original, child-resistant container with the label intact. Do not store in bathrooms or glove compartments where temperature and humidity can fluctuate. Keep out of reach of children and pets.
When traveling, pack your medication in a carry-on bag. Bring your prescription or a copy of the label for security checks and emergency refills. A weekly pill organizer may help maintain adherence while away from home. Temperature-controlled handling when required may apply to some medicines; your pharmacist can advise based on your specific items.
Benefits
Fibrates can lower very high triglycerides and increase HDL cholesterol. The treatment may reduce non-HDL cholesterol and apo B–containing particles in mixed dyslipidemia. Once-daily dosing simplifies routines for many patients. It can be combined with other lipid-lowering therapies when clinically appropriate.
Lifestyle remains the foundation. A heart-healthy diet, weight management, and regular physical activity can enhance lipid improvements. Alcohol reduction is often important when triglycerides are high. For additional context on statin therapy roles, see the article Lipitor Uses.
Side Effects and Safety
Common effects are usually mild and may improve with continued use. Contact your clinician if symptoms persist or worsen.
- Digestive upset or abdominal pain
- Headache or dizziness
- Elevated liver enzymes
- Back or joint pain
- Upper respiratory symptoms
- Rash or itching
Serious but less common risks can include myopathy or rhabdomyolysis, especially if combined with a statin, gallstones, pancreatitis, liver injury, and kidney effects. Seek urgent care for severe muscle pain, dark urine, intense abdominal pain, yellowing of the skin, or signs of allergic reaction. Some people ask about fenofibrate 145 mg brand name; multiple manufacturers and regional brands exist. Your pharmacist can review equivalence and substitution rules.
Drug Interactions and Cautions
Tell your clinician about all medicines and supplements you use. Interactions may occur with statins, warfarin and other anticoagulants, cyclosporine, and colchicine. Fibrates can increase bleeding risk with warfarin, and dose adjustments of the anticoagulant may be required. Combining with certain statins can raise muscle toxicity risk; careful selection and monitoring may be needed.
People with hypothyroidism or renal impairment may have higher myopathy risk when on combination therapy. Regular lab monitoring supports safe use. For additional background on these combinations, review Statin Drugs Diabetes and the overview in Statins and Diabetes.
What to Expect Over Time
Lipid changes are monitored through periodic blood tests. Your clinician may adjust therapy based on triglyceride and non-HDL cholesterol response, tolerability, and comorbid conditions. Consistent dosing, diet, and exercise usually provide the most stable results.
Expect follow-up to include liver and kidney function assessments per labeling and clinical practice. Report any new muscle pain, unexplained fatigue, or abdominal symptoms promptly. For those managing cardiometabolic risk, this therapy is one piece of a broader plan that may include statins, ezetimibe, or omega-3 products. If diabetes is present, see background on the relationship between triglycerides and glycemic control in Triglycerides and Diabetes.
Compare With Alternatives
Depending on your lipid profile, your prescriber may recommend additional or alternative therapies. A high-intensity statin such as Rosuvastatin can target LDL cholesterol reduction. For patients who need further LDL lowering or cannot tolerate higher statin doses, Ezetimibe may be considered. The right plan depends on your labs, risk factors, and tolerability.
Pricing and Access
You can review current pricing, compare manufacturers, and see availability before placing an order. Canadian pricing with US delivery helps many patients manage out-of-pocket costs. If you pay without insurance, evaluating multi-month fills can reduce per-fill fees and time between refills. Checkout is encrypted to protect your information.
Interested in seasonal offers or neutral updates? Visit our Promotions page. For general cardiovascular therapies, browse Cardiovascular to compare options.
Availability and Substitutions
Availability can vary by supplier and strength. If a specific presentation is out of stock, your prescriber may recommend an equivalent formulation or an alternative within the same class. Pharmacists can advise on substitution rules and whether your prescription allows generic interchange.
Patient Suitability and Cost-Saving Tips
Good candidates typically include adults with severe hypertriglyceridemia or mixed dyslipidemia who have tried diet and lifestyle changes. People with active liver disease, severe kidney impairment, or gallbladder disease should avoid this medicine. Those on anticoagulants or statins require closer monitoring.
To save on costs and time, consider 60- to 90-day fills if appropriate, and set refill reminders before you run low. Use one pharmacy for all lipid medications to simplify interaction checks. Keep a copy of your prescription for travel and future refills. Discuss generic options and whether a different strength or pack size offers better value.
Questions to Ask Your Clinician
- Is this treatment appropriate for my triglyceride and cholesterol goals?
- Should I take it with food based on my specific formulation?
- How will we monitor liver, kidney, and muscle safety over time?
- Could I combine this with a statin, and what risks should I watch for?
- What lifestyle changes would best support my lipid plan?
- If side effects occur, what are my options for adjustments or alternatives?
- How often should I repeat fasting lipid tests?
Authoritative Sources
For complete prescribing information and safety details, see the official label on DailyMed. Review comprehensive sections on indications, dosing, and monitoring before starting therapy. Access the FDA record here: DailyMed official labeling index for prescription products.
Manufacturer brand information can offer background on historical formulations and patient materials. Consult the company’s professional pages for specifics on indications and safety: AbbVie professional resources for legacy Tricor information.
For Canadian regulatory data, consult Health Canada’s database for product monographs and status: Health Canada Drug Product Database official search page.
Order when ready for prompt, express shipping and temperature-controlled handling when required. Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.
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What is the main use of fenofibrate?
It is used with diet to lower very high triglycerides and to treat primary hypercholesterolemia or mixed dyslipidemia. Your clinician will confirm suitability based on your lipid profile.
Can I take fenofibrate with a statin?
Some patients use both under medical supervision. The combination may raise muscle toxicity risk. Your clinician will assess benefits and risks and monitor for symptoms and lab changes.
How long before lipid levels improve?
Your clinician will check your response with periodic blood tests. Results vary by baseline values, adherence, and lifestyle changes. No specific timeline can be promised.
What are common side effects?
Digestive upset, headache, elevated liver enzymes, and back pain are reported. Serious effects like muscle injury, gallstones, pancreatitis, or liver injury are less common but require urgent care.
Who should not use fenofibrate?
Avoid use with active liver disease, severe kidney impairment, or gallbladder disease. Use is generally not recommended in pregnancy or during breastfeeding unless benefits clearly outweigh risks.
Do I need lab monitoring?
Yes. Lipid panels, liver enzymes, and kidney function are typically monitored at baseline and periodically during therapy. Monitoring frequency depends on your clinical situation.
How should I store the tablets?
Keep at room temperature, in a dry place away from light and moisture. Store in the original, child-resistant bottle and keep out of reach of children and pets.
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