Veterinarians prescribe Onsior cat medicine to help control pain and inflammation in cats. It contains robenacoxib, a selective NSAID that targets inflammatory pathways while sparing some protective functions. This overview explains approved uses, safety considerations, dosing forms, and practical tips for giving tablets at home. It also outlines how long effects may last and what to discuss with your veterinary team.
Key Takeaways
- Primary use: short-course pain and inflammation control in cats.
- Forms: flavored oral tablets and a clinic-only injectable option.
- Safety focus: monitor appetite, vomiting, stool changes, and hydration.
- Avoid drug overlaps: never combine with other NSAIDs or steroids unless directed.
Onsior cat medicine: What It Does and When To Use
Robenacoxib belongs to nonsteroidal anti-inflammatory drugs (NSAIDs). In clinical terms, it selectively inhibits cyclooxygenase-2 (COX-2), which moderates inflammatory mediators. In plain terms, it helps reduce swelling and discomfort so cats can rest, eat, and move more comfortably. Veterinarians commonly use it for short-term control of postoperative pain and for flare-ups of musculoskeletal discomfort. Labeling restricts duration, so plans emphasize brief courses and reassessment.
Your veterinarian determines if this medication suits your cat’s condition and health status. For details about tablet formulation and approved indications, see Onsior Cat, which provides product-specific background for cat owners. For a broader list of veterinary pain options, the Pain Inflammation category can help you compare therapeutic classes used in companion animals.
Independent agencies also summarize product evidence and risks; for overview information, consult the European assessment report for robenacoxib (European Medicines Agency dossier). For manufacturer guidance on indications and safe use, see the Elanco prescribing information presented for veterinarians and cat owners.
Forms, Dosing, and How To Give
Onsior is supplied as palatable oral tablets for at-home administration, and as a clinic-administered injection. Veterinarians set the dose and duration based on body weight, procedure type, and concurrent conditions. When you are instructed about onsior for cats how to give, follow the exact timing, number of tablets, and course length written on the label. Do not change the plan unless your veterinarian updates the instructions after re-evaluating your cat.
Many cats accept the flavored tablet by hand, a pill pocket, or a small treat. If your cat refuses, your veterinary team can demonstrate a safe pilling technique. Some cats benefit from giving the tablet with a small amount of food to improve acceptance, provided the entire dose is consumed. For context on other NSAID formats used in cats, compare clinic injectables such as Metacam Solution For Injection, and liquid home-use options like Metacam Oral Suspension For Cats, which show how formulation shapes administration planning. For a wider reading list on discomfort management in pets, visit Pain Inflammation articles to understand symptom patterns and care strategies.
Tip: Prepare the tablet dose before mealtime, and log the time given. A simple notebook or phone reminder helps you avoid double dosing or missed administrations.
Safety Profile and Side Effects
Like all NSAIDs, robenacoxib may cause gastrointestinal or renal adverse effects. Watch for appetite loss, vomiting, diarrhea or black tarry stool, increased thirst, or lethargy. If you notice potential onsior for cats side effects, stop the medication and contact your veterinarian promptly. Cats with dehydration, kidney disease, or a history of GI ulcers require extra caution. Bloodwork and hydration assessments may be recommended before and during therapy for higher-risk patients.
Do not combine robenacoxib with any other NSAID or corticosteroid unless a veterinarian explicitly directs a transition plan. Overlapping these drugs can raise the risk of ulcers and kidney stress. Your vet may pair different drug classes, such as opioids or gabapentin, with NSAIDs when appropriate. For a comparative view of canine NSAIDs and why species-specific labeling matters, see Deramaxx For Dogs, which highlights important differences between dog and cat medications.
Contraindications and Interactions
Robenacoxib is contraindicated in cats with known hypersensitivity to NSAIDs or with gastrointestinal ulceration. It is generally avoided in dehydrated, hypovolemic, or hypotensive patients due to renal risk. Concurrent use with other NSAIDs, aspirin, or corticosteroids (e.g., prednisolone, dexamethasone) can increase the likelihood of GI injury and must be avoided unless your veterinarian designs a washout strategy. Use caution when combining with nephroactive agents; monitor hydration and kidney parameters as directed. If your cat has endocrine, hepatic, or cardiac disease, your veterinarian will weigh the benefit-risk profile carefully and may adjust the plan or select a different analgesic.
For manufacturer and regulator-reviewed risk summaries, consult the European assessment report, which distills clinical, safety, and pharmacology data for veterinary teams and pet owners.
Duration and Pharmacology
Owners often ask how long does onsior last in cats. Robenacoxib has a relatively short blood half-life but demonstrates tissue selectivity, meaning it concentrates at inflamed sites while clearing from circulation faster. In practical terms, veterinarians typically use once-daily schedules for brief periods, reassessing response and tolerance. This approach aims to match the drug’s pharmacokinetic profile to clinical needs while respecting safety margins.
The medication’s COX-2 selectivity may help limit some COX-1–related adverse events, though no NSAID is risk-free. Your veterinarian will tailor timing to surgery type, pain intensity, and medical history. If pain persists beyond the planned course, your vet may adjust therapy or consider alternatives. For cats with concurrent illnesses like pancreatic inflammation, pain plans may differ; see Pancreatitis In Cats for context on disease-specific management considerations.
After Surgery and Multimodal Plans
Many clinics include robenacoxib in perioperative protocols for soft-tissue procedures. When considering onsior for cats after surgery, veterinarians often start analgesia before or during anesthesia and continue a short postoperative course. They may pair NSAIDs with other classes, such as opioids, to target different pain pathways. The exact combination and duration depend on the procedure, exam findings, appetite, and hydration.
Always report changes in behavior, food intake, or litter-box habits during recovery. Hydration and a calm environment help healing and reduce stress-related complications. If NSAIDs are unsuitable, your veterinarian may recommend another option. For example, Metacam is a meloxicam-based NSAID used under specific feline protocols, and decisions are based on case-by-case risk-benefit assessments.
Interactions, Schedules, and Special Populations
Ask your veterinary team about onsior with other pain meds cats when planning multimodal analgesia. Some combinations, like buprenorphine or gabapentin, may be appropriate under supervision. In contrast, concurrent NSAIDs or steroids raise safety concerns and are typically avoided without a washout period. Dose intervals and total course length are individualized; older cats, or those with kidney or liver disease, may require extra monitoring and shorter courses. Geriatric cats also benefit from hydration, nutrition support, and environmental modifications.
If your cat has chronic inflammatory pain, your veterinarian may choose other long-term strategies after a short NSAID course. Non-NSAID options, joint-supporting measures, or disease-modifying plans may follow. To understand how inflammation intersects with other feline conditions, see Pancreatitis And Diabetes In Cats for systemic considerations. For contrasts with antimicrobials used in pets, the Doxycycline Guide explains how antibiotics differ from pain medicines in role and risks.
Owner Reports and Practical Tips
Owners sometimes ask, will onsior make cats sleepy. Sedation is not typical for NSAIDs; if your cat seems unusually drowsy, contact your veterinarian to rule out illness, dehydration, or overlapping medications. Rare behavioral changes can occur, though they are not expected. Nausea or reduced appetite may signal GI irritation; stopping the drug and seeking guidance is prudent.
To give tablets at home, handle gently and avoid repeated attempts that create stress. Use a pill pocket or a tiny flavorful treat, and follow with water or a small meal if allowed. If pilling is difficult, ask your veterinary team to demonstrate a safe method. For broader feline wellness topics that support recovery and comfort, explore Pet Health features. For examples of non-NSAID feline therapies used for other conditions, see Atopica For Cats to understand how treatment classes differ.
Note: Keep a simple symptom diary during therapy. Record appetite, water intake, litter-box output, energy, and any vomiting or stool changes to support accurate veterinary reassessment.
Recap
Robenacoxib helps reduce feline pain and inflammation during short, supervised courses. Work closely with your veterinarian to tailor timing, monitor for adverse effects, and adjust plans as needed. Consistent dosing, hydration, and early reporting of concerns improve comfort and safety.
This content is for informational purposes only and is not a substitute for professional medical advice.


