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Abilify® Tablets for Schizophrenia
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Abilify is a prescription antipsychotic for certain psychiatric conditions. It is used to help manage symptoms in adults and some children. Patients evaluating Abilify without insurance may also discuss aripiprazole as a lower-cost option with their prescriber.
What Abilify Is and How It Works
You can place orders with US delivery from Canada for this medicine. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order. Abilify® contains aripiprazole, an atypical antipsychotic. It acts as a partial agonist at dopamine D2 and serotonin 5‑HT1A receptors, and as an antagonist at 5‑HT2A receptors. This mixed activity can help balance neurotransmitters linked with psychosis, mood symptoms, and irritability. The treatment is available as aripiprazole tablets for daily oral use.
For condition education, see our overview of Schizophrenia. You can also browse broader topics in our Mental Health category.
Who It’s For
This drug is indicated for adults with schizophrenia. It is also used for acute manic or mixed episodes and maintenance in bipolar I disorder, either alone or with mood stabilizers. As adjunctive therapy, it may be added to antidepressants for major depressive disorder when response is inadequate. It treats irritability associated with autistic disorder and is used for Tourette’s disorder in pediatric patients.
Individuals with known hypersensitivity to aripiprazole should avoid this treatment. It carries a boxed warning for increased mortality in elderly patients with dementia-related psychosis; it is not approved for this use. Patients with a history of severe cardiovascular disease, seizure disorders, or impulse-control problems should discuss risks with their clinician. When appropriate, prescribers may consider Abilify generic instead of the brand version.
Learn about related conditions including Bipolar Disorder, Depression, and Tourette Syndrome to understand labeled uses.
Dosage and Usage
Use exactly as prescribed and follow the approved label. Tablets are taken by mouth once daily, with or without food. Swallow whole with water. Do not split or crush unless your prescriber advises. For schizophrenia, many adults start at doses within the label’s recommended range and may be adjusted based on response and tolerability. For bipolar I disorder and adjunctive use in major depression, dosing follows indication-specific schedules on the official label. Ask your clinician or pharmacist if you need help aligning doses with your current regimen.
Some patients are prescribed Abilify 10 mg tablets; your actual dose may differ. Dose adjustments can be necessary with strong CYP2D6 or CYP3A4 inhibitors or inducers. If your clinician changes another interacting medication, they may revisit the plan for this antipsychotic.
Strengths and Forms
Oral tablets are commonly available in 2 mg, 5 mg, 10 mg, 15 mg, 20 mg, and 30 mg strengths. Orally disintegrating tablets and an oral solution exist in some markets. Long-acting injectable forms of aripiprazole also exist but are supplied under different product names. Availability can vary by pharmacy and jurisdiction.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember the same day. If it is nearly time for the next dose, skip the missed tablet and resume your regular schedule. Do not double doses. Consistent daily timing can help maintain steady levels and reduce symptom fluctuation. Set reminders if you find it hard to keep a routine.
Storage and Travel Basics
Store tablets at room temperature in the original container. Keep the bottle closed, dry, and away from excess heat and light. Protect from moisture and do not store in a bathroom. Keep out of reach of children and pets.
When traveling, carry your medication in your hand luggage along with a copy of your prescription. A current medication list helps with security checks and emergency care. If crossing borders, keep tablets in labeled pharmacy packaging. Pack only what you need plus a small buffer as advised by your prescriber or pharmacist.
Benefits
This antipsychotic may help reduce positive symptoms such as hallucinations and delusions in schizophrenia. It may also improve associated mood and cognitive symptoms. In bipolar I disorder, it can help control manic or mixed episodes and support maintenance treatment. As an add-on for major depression, it can help when antidepressants alone are not enough. Once-daily dosing offers convenience for long-term therapy.
Side Effects and Safety
- Common effects: nausea, vomiting, constipation, headache
- Restlessness or akathisia: inner sense of unease or need to move
- Anxiety or insomnia: sleep trouble or nervousness
- Dizziness or lightheadedness: especially when standing up quickly
- Fatigue or sedation: tiredness during the day
- Weight gain or appetite changes: variable by person
- Tremor or muscle stiffness: may occur at some doses
Serious risks can include neuroleptic malignant syndrome, tardive dyskinesia, compulsive behaviors, orthostatic hypotension, leukopenia, and seizures. Metabolic changes, including elevated blood glucose and lipids, can occur; monitor for symptoms of hyperglycemia. There is a boxed warning related to suicidal thoughts and behaviors in children, adolescents, and young adults with major depressive disorder when used as adjunctive therapy. Older adults with dementia-related psychosis have increased mortality risk and should not use this drug for that condition. Report sudden changes in mood, behavior, or movement symptoms to your clinician promptly.
For a fuller overview, read our Side Effects Guide written for patients and caregivers.
Drug Interactions and Cautions
Strong CYP3A4 inhibitors (such as ketoconazole, clarithromycin) or CYP2D6 inhibitors (such as fluoxetine, paroxetine) can increase aripiprazole levels. Strong CYP3A4 inducers (such as carbamazepine, rifampin) can lower exposure. Alcohol and other CNS depressants can increase sedation and impair judgment. Use caution with antihypertensive agents due to potential additive effects on blood pressure. Be mindful of dehydration or overheating risk, which can worsen side effects. Patients with diabetes or prediabetes should monitor glucose and weight during therapy. For context on cardiometabolic health, see Mental Health and Diabetes.
What to Expect Over Time
Response varies by diagnosis, dose, and concurrent therapy. Some symptoms may improve gradually with steady, daily use. It can take time for mood or cognitive changes to stabilize. Keep taking the medication as directed unless your prescriber tells you to stop. Regular follow-up allows assessment of benefits and tolerability. Tracking sleep, appetite, and activity can help you and your clinician align goals.
To learn more about labeled uses and roles in therapy, read Abilify Uses for practical context.
Compare With Alternatives
Other atypical antipsychotics and mood-stabilizing options may be considered based on your diagnosis and history. For schizophrenia and bipolar spectrum conditions, prescribers sometimes evaluate Latuda® for efficacy and tolerability needs. In bipolar maintenance or as adjuncts in select cases, agents like Lamictal may also be part of a plan. Choice depends on clinical factors, side-effect profiles, and prior response.
Pricing and Access
We reflect Canadian pricing with transparent checkout and US shipping from Canada. If you are comparing options, review the current Abilify price on the product page before placing an order. Generic aripiprazole can lower out-of-pocket costs in some cases. For potential extra savings, see active Promotions when available. Final costs vary by strength, fill quantity, and dispensing pharmacy.
Availability and Substitutions
Supply can vary by strength and form. If a selected dose is temporarily unavailable, a prescriber may recommend an alternative strength or a different atypical antipsychotic. When appropriate, you can buy Abilify online or request aripiprazole as a therapeutically equivalent option. Pharmacist review and a valid prescription are required.
Patient Suitability and Cost-Saving Tips
This medicine may be suitable for adults diagnosed with schizophrenia, bipolar I disorder, or those needing adjunctive therapy for major depression. Pediatric use applies to specific conditions and ages per the label. Patients with high cardiometabolic risk, a history of movement disorders, or uncontrolled seizures may require closer monitoring or a different therapy.
For budget planning, ask your prescriber about longer fills if stable on a dose. Multi-month supplies can reduce per-fill fees and help adherence. Setting calendar reminders supports on-time refills. Discuss copay cards or patient assistance when available in your region. You can also explore Abilify savings by comparing brand and generic aripiprazole under your clinician’s guidance.
Questions to Ask Your Clinician
- Primary goal: what symptoms should improve first
- Dose plan: starting strength and titration approach
- Monitoring: weight, glucose, and movement checks
- Interactions: managing other prescriptions or supplements
- Duration: how long to continue if stable
- Alternatives: options if side effects occur
Authoritative Sources
For the full US Prescribing Information, consult the FDA label via DailyMed; you can review details on dosing, warnings, and interactions at DailyMed’s official aripiprazole listing. For manufacturer information, see Otsuka’s product resources detailing indications and safety at Otsuka’s product information page. For Canadian regulatory data, consult Health Canada’s database entry at Health Canada Drug Product Database.
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Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.
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What conditions does Abilify treat?
It is indicated for schizophrenia in adults, bipolar I disorder (manic or mixed episodes and maintenance), adjunctive treatment of major depressive disorder in adults, irritability associated with autistic disorder, and Tourette’s disorder in pediatric patients.
How should I take Abilify tablets?
Take once daily exactly as prescribed. Swallow tablets whole with water, with or without food. Do not change your dose or stop suddenly without consulting your prescriber.
What are common side effects of Abilify?
Common effects include nausea, vomiting, constipation, headache, restlessness, dizziness, anxiety, insomnia, fatigue, and weight gain. Serious risks like neuroleptic malignant syndrome or tardive dyskinesia are rare but require urgent care.
Does Abilify interact with other medicines?
Yes. Strong CYP3A4 or CYP2D6 inhibitors can increase levels, and strong CYP3A4 inducers can decrease levels. Alcohol and CNS depressants may increase sedation. Tell your clinician about all medicines and supplements.
How do I store Abilify tablets?
Store at room temperature in the original, closed container. Keep dry, away from excess heat and light, and out of reach of children and pets.
Is generic aripiprazole equivalent to Abilify?
Aripiprazole is the FDA-approved generic for Abilify. It has the same active ingredient and labeled strength; inactive ingredients can differ. Your prescriber or pharmacist can advise on substitution.
What happens if I miss a dose?
Take the missed dose the same day when remembered. If it is close to your next dose, skip the missed dose. Do not double up. Resume your normal schedule and ask your clinician if unsure.
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