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Zycortal® Suspensión inyectable para la enfermedad de Addison canina
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Zycortal® is a veterinary mineralocorticoid therapy for dogs with primary hypoadrenocorticism. It helps replace aldosterone-like activity to stabilize sodium and potassium. This page explains how it works, who it suits, and how to use it safely. You can access US delivery from Canada, even if you are paying without insurance.
Qué es Zycortal y cómo funciona
This medicine contains desoxycorticosterone pivalate, a long-acting mineralocorticoid. It supports fluid and electrolyte balance in dogs with Addison’s disease. As a Inyección DOCP para la enfermedad de Addison canina, it is typically given about monthly after stabilization. It does not replace glucocorticoids, so a separate steroid, often prednisone, is usually needed. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.
The treatment is administered by subcutaneous injection. It increases sodium reabsorption and potassium excretion in the kidneys. Your veterinarian adjusts timing and dose based on clinical response and blood electrolyte results.
Who It’s For
This therapy is indicated for dogs diagnosed with primary hypoadrenocorticism. It is not a substitute for glucocorticoid replacement. Dogs with uncontrolled heart disease, edema, or significant kidney impairment require caution because the drug can promote sodium and water retention. Puppies, pregnant, or nursing animals should be assessed carefully by a veterinarian.
The product is a Desoxycorticosterone pivalate for dogs suspension intended for use under veterinary supervision. Cats are not typical candidates. Tell your veterinarian about all existing conditions and current medicines before starting therapy.
Posología y utilización
Veterinarians often begin with a weight-based dose and then individualize the interval. Injections are given subcutaneously. Electrolytes are checked during the first month and periodically thereafter to guide adjustments. A glucocorticoid is commonly co-prescribed. Do not change the dose or interval without veterinary direction.
Initial follow-up typically includes sodium and potassium checks within two weeks, then again around the end of the first dosing interval. Your veterinarian will set the schedule for Desoxycorticosterone pivalate monitoring intervals based on your dog’s response and lab values.
Fortalezas y formas
This medicine is supplied as a multi-dose injectable suspension at 25 mg/mL concentration. Common vial sizes include 4 mL and 10 mL. Availability can vary by pharmacy and over time.
Packaging is intended for multi-use until the in-use period or expiry, as directed on the official label. Your pharmacist can confirm current presentations.
Dosis omitida y momento oportuno
If a scheduled injection is missed, contact your veterinarian for guidance. Do not double up. Watch for signs that may indicate electrolyte imbalance such as lethargy, vomiting, diarrhea, weakness, or tremors. Your veterinarian may recommend lab checks before resuming the usual interval.
Maintain a consistent schedule once stabilized. Keep a calendar or reminder system to prevent gaps that could lead to relapse of Addisonian signs.
Almacenamiento y viaje
Store vials at controlled room temperature as directed by the label. Protect from freezing. Keep in the original carton or a light-protective area. Shake as directed before each withdrawal so the suspension is uniform. Always keep medicines out of reach of children and pets.
When traveling, carry the vial, syringes, and copies of veterinary prescriptions. Use a sturdy case to prevent breakage and leaks. Pack a small sharps container. Ask your veterinarian for a travel letter if you will carry needles. Do not use the vial if the suspension will not resuspend, appears discolored, or contains large clumps; consult your veterinarian or pharmacist.
For preventive care while traveling, your veterinarian may also recommend parasite control options. See our product pages such as Revolución para perros for year-round protection guidance.
Manipulación de bolígrafos y eliminación de objetos punzantes
This product comes in a vial, not a pen. Before withdrawing each dose, mix the suspension as directed by the label. Use a sterile needle and syringe for each injection. Wipe the vial stopper with alcohol before puncture. Withdraw slowly to reduce bubbles. Confirm dose markings carefully.
Dispose of used needles and syringes immediately in an approved sharps container. Do not recap needles. Follow local rules for sharps disposal. Ask your clinic for a take-back program or guidance on safe disposal in your area.
Beneficios
This mineralocorticoid therapy helps maintain sodium and potassium balance in dogs with Addison’s. Many dogs can transition to a stable schedule after an initial adjustment period. Subcutaneous dosing avoids intramuscular injections for most patients. Multi-dose vials can support long-term management under veterinary supervision.
Efectos secundarios y seguridad
- Aumento de la sed o de la micción
- Edema o retención de líquidos
- Diarrhea or vomiting
- Disminución del apetito
- Letargo o debilidad
- Behavior changes such as restlessness or panting
Report possible adverse effects promptly. Serious concerns may include hypertension, arrhythmias, electrolyte disturbances, or signs of fluid overload such as cough and breathing difficulty. Overdosage may produce signs consistent with mineralocorticoid excess or alkalosis. For more details on Efectos secundarios de Zycortal en perros, refer to the official product insert and your veterinarian’s guidance. For vomiting management education, see Cerenia Comprimidos.
Interacciones medicamentosas y precauciones
Tell your veterinarian about all medicines and supplements. Use caution with diuretics, ACE inhibitors, or other drugs that affect electrolytes or blood pressure. NSAIDs may increase renal risks in susceptible animals. Concurrent glucocorticoids are usually required but should be managed by a veterinarian to avoid excessive steroid exposure. Your veterinarian may monitor renal parameters when other nephroactive drugs are used.
If infection is suspected, antibiotics may be prescribed. For background on common canine antibiotics, see articles such as Clavamox para perros y Cefalexina para perros.
Qué esperar con el tiempo
Clinical improvement often follows correction of dehydration and electrolyte imbalance. Ongoing management focuses on keeping sodium and potassium within target ranges and preventing relapses. Your veterinarian may adjust the interval or dose after reviewing lab values and your observations at home. Keep a log of appetite, thirst, activity, and any gastrointestinal signs. Share these notes during follow-ups to aid fine-tuning.
Comparar con alternativas
Another approved mineralocorticoid option is Percorten V, which contains DOCP in a different branded formulation. Some clinicians also consider fludrocortisone tablets, a synthetic corticosteroid with mineralocorticoid activity, particularly when injection access is limited. Your veterinarian will help choose the approach best aligned with your dog’s diagnosis, co-morbidities, and your ability to follow the dosing plan.
Precios y acceso
We list current options so you can review the Desoxycorticosterone pivalate injection price by vial size. Fulfillment includes licensed Canadian pharmacies, with items that Ships from Canada to US. You can review the cash price for Zycortal, compare typical market quotes, and decide what suits your budget.
Savings CTA: Explore Canadian pricing and see potential savings versus typical local costs. Pricing CTA: View live availability and select your vial size to see today’s pricing. For offers when available, check our Promociones página.
Disponibilidad y sustituciones
Stock can vary by vial size. If the 10 mL is unavailable, your prescriber may recommend the 4 mL vial or another DOCP brand. Ask your veterinarian before switching between products. If access is an issue, your clinic may administer in-house until your order arrives.
Puede Order Zycortal 4 mL vial online when prescribed. For broader selection across pet therapies, browse our Medicamentos para mascotas categoría.
Adecuación al paciente y consejos para ahorrar costes
This therapy may suit dogs with confirmed primary hypoadrenocorticism who can receive periodic injections and monitoring. It may not suit dogs with uncontrolled congestive heart failure or severe renal disease without close oversight. Your veterinarian will decide if this mineralocorticoid is appropriate and whether a glucocorticoid is also indicated.
Cost-saving tips: consider multi-month orders if your prescription allows; ask your clinic to align rechecks with refill cycles; set refill reminders to avoid urgent visits; and discuss training for at-home injections if your veterinarian deems it appropriate. If comparing sources, search using terms like Desoxicorticosterona pivalato 25 mg/mL comprar online to understand available DOCP presentations.
Preguntas para su médico
- Initial plan: target dose, interval, and lab check timing
- Glucocorticoid: which steroid, how long, and what signs to watch
- Monitoring: symptoms that should prompt an unscheduled visit
- Home care: injection technique, mixing steps, and safe disposal
- Comorbidities: kidney or cardiac concerns that change monitoring
- Travel: how to store the vial and carry supplies safely
Fuentes autorizadas
| Fuente | Enlace |
|---|---|
| Página de producto de Dechra Zycortal | Manufacturer |
| FDA Medicamentos para animales @ FDA | FDA CVM |
| Base de datos de medicamentos de Health Canada | DPD |
Ready to proceed? Place your prescription request with US shipping from Canada and prompt, express, cold-chain shipping with temperature-controlled handling when required. This information is educational and not a substitute for your veterinarian’s advice.
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- Productos envasados en seco $25.00
- Productos envasados en frío $35.00
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El envío con este método tarda entre 5 y 10 días
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How is this mineralocorticoid injectable given?
Veterinarians usually give the first dose in-clinic, then set a schedule for repeat injections based on response. It is injected subcutaneously using a sterile needle and syringe. The vial must be mixed as directed so the suspension is uniform before withdrawal. A glucocorticoid, such as prednisone, is commonly prescribed alongside for full hormone replacement. Your clinic may train you for at-home administration if appropriate, and will outline follow-up lab checks to ensure electrolytes remain in range.
What monitoring is recommended after starting therapy?
Your veterinarian typically checks serum sodium and potassium within the first couple of weeks and again near the end of the first dosing interval. If adjustments are needed, follow-up may be more frequent until stability is achieved. After stabilization, periodic rechecks are advised. The exact schedule depends on your dog’s health, concurrent medicines, and clinical signs. Keep notes on thirst, appetite, energy, and any gastrointestinal symptoms to share during visits.
Can my dog still need a steroid with this injection?
Yes. This medicine replaces mineralocorticoid activity but not glucocorticoids. Most dogs require a low-dose steroid like prednisone, at least initially and sometimes long term. Your veterinarian will determine the plan and tapering strategy if appropriate. Report any changes in appetite, vomiting, diarrhea, or lethargy promptly, since these signs may reflect the need for dose or interval adjustments for either hormone component.
What are important side effects to watch for?
Increased thirst and urination, fluid retention, vomiting, diarrhea, and reduced appetite can occur. Serious concerns include electrolyte imbalance, high blood pressure, or signs of fluid overload such as cough, breathing difficulty, or exercise intolerance. If you observe weakness, tremors, collapse, or persistent gastrointestinal issues, contact your veterinarian immediately. Never change doses on your own. Your clinic may check blood pressure and labs if adverse effects are suspected.
What if a dose is missed or delayed?
Contact your veterinarian for instructions. Do not administer extra volume to compensate. Your veterinarian may recommend a lab check before resuming the schedule if signs of Addison’s recur. Keep a written calendar, phone reminders, and a refill plan to prevent gaps. If your dog shows signs like vomiting, diarrhea, lethargy, or weakness during a delay, seek veterinary care. Consistent dosing and monitoring help maintain stable electrolytes over time.
¿Cómo debe almacenarse y manipularse el vial?
Follow the label: store at controlled room temperature and protect from freezing. Keep in the carton or a dark place, and mix the suspension as directed before each dose. Use a new sterile needle and syringe for every injection. If you see clumping that does not disperse with mixing, or discoloration, consult your veterinarian or pharmacist before use. Always store medicines out of reach of children and pets, and dispose of sharps in an approved container.
Is this medicine appropriate for dogs with heart or kidney disease?
Caution is advised because mineralocorticoids can cause sodium and water retention. Dogs with uncontrolled heart failure or significant renal impairment may need closer monitoring, dose adjustments, or an alternative plan. Your veterinarian will weigh risks and benefits, check electrolytes and renal parameters, and tailor follow-up visits. Provide a complete list of medicines and supplements, since drugs like diuretics or ACE inhibitors can interact and influence fluid balance.
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