Revolution® Topical Solution for Dogs

This topical solution helps prevent heartworm and control fleas and mites in dogs. This page explains what it is, how to use it, and key safety points.

What Revolution Is and How It Works

Revolution® topical solution contains selamectin for broad parasite control in dogs. Revolution selamectin for dogs is applied once monthly to the skin. You can order it with US delivery from Canada, even if you are paying without insurance.

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This medicine distributes systemically after application. It prevents heartworm by killing infective larvae, kills adult fleas, and prevents flea eggs from developing. It treats ear mites and sarcoptic mange. In dogs, it also controls the American dog tick. Use only as directed by your veterinarian.

Who It’s For

This treatment is for puppies and dogs six weeks of age and older. Selamectin for dogs helps prevent heartworm disease and treats or controls fleas, ear mites, sarcoptic mange, and a single tick species. Do not use on unwell or underweight animals without veterinary guidance. Your veterinarian may test for heartworm infection before starting preventive therapy. For other pet therapies, browse our Pet Medications catalog. If scratching leads to skin infections, see our Cephalexin For Dogs overview.

Dosage and Usage

Apply the entire contents of one single-use tube once every month. Selamectin for dogs is applied only to the skin, never by mouth. Choose the pack that matches your dog’s weight.

1. Remove one tube from the foil pouch and hold it upright.
2. Press the cap firmly to puncture the seal, then remove the cap.
3. Part the hair at the base of the neck until the skin is visible.
4. Place the tip on the skin and squeeze all contents in one spot.
5. Keep your dog dry for at least two hours. Delay bathing the site until the next day.
6. Wash your hands after use, and keep the area away from open flame until dry.

Apply to intact skin only. Do not massage into the coat. Keep the tip away from eyes and mouth. Prevent other pets from licking the site until it is dry. If a dose is expelled or obviously lost, contact your veterinarian for guidance.

Strengths and Forms

This topical solution is supplied in color-coded, single-use tubes. Revolution doses for dogs align with body‑weight bands such as 5–10 lb, 10.1–20 lb, 20.1–40 lb, 40.1–85 lb, and 85.1–130 lb. Each tube contains a ready-to-apply amount of selamectin. Availability may vary by size.

Missed Dose and Timing

If you miss a monthly dose, apply when you remember and then resume monthly use. Do not double up or apply two tubes at once. Keeping a calendar reminder can help maintain a 30‑day rhythm.

Storage and Travel Basics

Store tubes at room temperature in the original packaging. Protect from heat and direct sunlight. Do not allow children or other pets to access opened tubes. The solvent is flammable until dry; keep away from flames and heat sources. For travel, keep the carton and prescription with you, and pack tubes in a sealed bag to prevent leaks. If flying, carry doses in your hand luggage with the prescription label to avoid temperature extremes. Our shipments use temperature-controlled handling when required.

Benefits

Revolution flea and tick for dogs provides broad monthly coverage in one application. The solution prevents heartworm disease, kills adult fleas, and halts flea egg development. It treats ear mite infestations. In dogs, it also controls the American dog tick. One monthly application reduces the need to juggle multiple products. For itch management related to allergies, see End The Scratching.

Side Effects and Safety

• Application site effects: transient hair loss, redness, or dandruff.
• Gastrointestinal upset: vomiting or soft stool in some dogs.
• Itching or restlessness: brief scratching after application.
• Lethargy: mild tiredness reported occasionally.
• Reduced appetite: short-lived decrease in food interest.

Serious but uncommon events can include muscle tremors, incoordination, or seizures. Dogs with a history of neurologic disorders or herding breeds with drug-sensitivity may require extra caution. Keep treated pets away from flames until the site is dry. If human skin contact occurs, wash with soap and water. Seek veterinary care if signs persist or worsen. For more on antibiotic reliability in pets, read How Reliable Is.

Drug Interactions and Cautions

Use this medicine under veterinary supervision if your dog receives other parasite preventatives, sedatives, or systemic corticosteroids. Combining multiple endectocides can increase the chance of neurologic effects. Do not apply on broken skin. Keep all current medicines on hand so your veterinarian can review them. Learn about common pet antibiotics in Explore Doxycycline For.

What to Expect Over Time

With consistent monthly use, you may see fewer fleas on your dog and in the home environment. Some fleas can still appear as adults emerge from cocoons in the surroundings; continued monthly use helps break this cycle. Ear mite signs may ease as infestations resolve. Ticks that the solution controls may be reduced after treatment. Your veterinarian may recommend environmental cleaning and yard control to support results over time.

Compare With Alternatives

If you prefer a chewable that targets fleas and a wider range of tick species, consider Simparica®. For a heartworm‑only preventive that pairs well with a separate flea product, Heartgard® is a common choice. Your veterinarian can advise which spectrum best fits your dog and region.

Pricing and Access

Our platform lists Canadian pricing with transparent checkout. Orders ship in original packaging and include pharmacist support when required. Ships from Canada to US is available for eligible addresses. You can view current pricing by selecting your dog’s weight and starting checkout. Many pet owners pay cash; this can still be affordable without insurance. Ask your veterinarian for a prescription if one is required.

Availability and Substitutions

Supply can vary by tube size. If a size is unavailable, your prescriber may recommend an alternative strength pack or a different preventive with a similar spectrum. Do not substitute products without veterinary guidance, as ingredients and tick coverage differ by brand.

Patient Suitability and Cost-Saving Tips

Revolution for small dogs uses tubes calibrated to lower weight ranges, while larger dogs need higher volume packs. Dogs with intact skin, reliable monthly routines, and no history of seizures may be good candidates. If your pet swims often, ask whether a different product class is better. To save, consider a multi‑month supply, set refill reminders, and keep one spare dose for travel. Combine monthly reminders with your heartworm testing schedule to maintain continuity. Store remaining tubes in one place so you can track when to reorder.

Questions to Ask Your Clinician

• Is my dog ready for monthly prevention now?
• Should we test for heartworm infection before starting?
• Which weight band is correct today?
• Can I combine this with my current flea collar or shampoo?
• How soon after bathing should I apply a dose?
• What side effects should I watch for in my dog?
• When should we recheck to confirm control?

Authoritative Sources

Zoetis Product Page

FDA Animal Drugs Database

Health Canada Drug Product Database

Ready to proceed? Start your order now for prompt US shipping from Canada. Use as directed by your veterinarian; this page is informational and not a substitute for professional advice.