Cancer Articles
Metformin in Prediabetes: Role in Prevention and Impact on Vitamin B12 Absorption
Understanding PrediabetesPrediabetes is a metabolic condition where blood sugar levels are higher than normal but not high enough to be classified as type 2 diabetes. It is diagnosed using criteria…
Colorectal Cancer (CRC) and Metformin: A Promising Combination for Prevention and Treatment in Diabetic Individuals
Colorectal cancer (CRC) is the third most common malignancy worldwide for both men and women. According to the World Health Organization (WHO), approximately 1.9 million new cases were diagnosed in…
Osteosarcoma: Metformin’s Potential Future Role in Treatment
Osteosarcoma is the most common type of primary bone cancer, affecting adolescents and young adults at an incidence rate of 3-4 cases per million people annually. This aggressive malignancy usually…
Can Metformin Revolutionize the Treatment of Acute Lymphoblastic Leukemia (ALL)?
Acute lymphoblastic leukemia (ALL) is a cancer affecting lymphocytes, primarily impacting children but also prevalent in adults over 50. With an incidence rate of 1-4 per 100,000 globally, ALL is…
Metformin and Endometrial Cancer: A Comprehensive, Evidence-Based Overview (2024)
Endometrial cancer is one of the most common gynecological cancers, particularly affecting postmenopausal women. With obesity rates rising and contributing to increased estrogen levels, the incidence of endometrial cancer continues…
How Metformin Ameliorates the Metabolic Side Effects of Antiretroviral Therapy (ART) in HIV Patients
Metformin has gained attention for its potential to alleviate metabolic side effects associated with Antiretroviral Therapy (ART) in HIV patients. These side effects, including insulin resistance and fat redistribution (lipodystrophy),…
Is Metformin a Sulfonylurea? Understanding the Difference
Metformin’s origins trace back to the herb Galega officinalis (goat’s rue), which was historically used to manage diabetes symptoms in medieval Europe. The drug was first approved in 1957 in…
Could Metformin and Rapamycin Revolutionize Rheumatoid Arthritis Treatment?
Introduction to Rheumatoid Arthritis and Current TreatmentsRheumatoid arthritis (RA) is a chronic autoimmune disease marked by joint inflammation and cartilage damage. Current treatments for RA primarily involve drugs that suppress…
How Metformin Fights Cancer: A Multi-Mechanistic Approach
Metformin, a well-known diabetes medication, has shown promise in cancer treatment due to its ability to target multiple pathways. Here’s how Metformin combats cancer:In this article, we’ll focus on how…
How Metformin Impacts Cancer Metabolism: A Simple Overview
Metformin, a common diabetes medication, has shown significant potential in fighting cancer. Its impact on how cells produce energy, particularly in mitochondria, has been effective against various cancers, including breast,…
Metformin’s Impact on Cancer Metabolism
This section delves deeper into the mechanisms by which Metformin acts as an anti-cancer medication. Notably, Metformin’s influence on mitochondrial energy metabolism shows significant efficacy against breast, prostate, pancreatic, lung,…
Metformin’s Anti-Cancer Properties: A Deep Dive into Its Biochemical Mechanism
What is Metformin?Metformin is a commonly prescribed diabetes medication, but recent studies reveal it may also have powerful anti-cancer properties. Research shows that Metformin can inhibit the growth of several…