Sudafed® Sinus Advance with Ibuprofen Caplets for Sinus Congestion and Pain

Sudafed Sinus Advance® with ibuprofen is a combination caplet for sinus pressure, congestion, headache, and aches. This page explains uses, safety, and how to access it with US delivery from Canada. You can review pricing options without insurance.

What Sudafed Is and How It Works

This medicine contains pseudoephedrine to shrink swollen nasal passages and ibuprofen to reduce pain and inflammation. As a decongestant pain reliever ibuprofen pseudoephedrine, it eases sinus pressure and related discomfort. The decongestant acts on nasal blood vessels, while the NSAID targets inflammation that contributes to pain. Together, they may improve airflow and reduce headache from sinus pressure.

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Use this treatment for short-term relief of symptoms tied to Nasal Congestion and head cold discomfort. Always follow the Drug Facts label and any directions from a clinician.

Who It’s For

Intended for adults and adolescents 12 years and older with sinus pain, pressure, nasal blockage, headache, or fever related to colds or allergies. Those with aspirin or NSAID allergy, active stomach ulcers, recent GI bleeding, severe kidney disease, or after coronary bypass should not use it. Avoid if you are taking or recently took an MAOI. People with high blood pressure, heart disease, thyroid disease, diabetes, glaucoma, or prostate enlargement should ask a clinician before use.

These OTC pseudoephedrine ibuprofen caplets may help when sinus inflammation causes facial pressure. For ongoing or severe issues, evaluation for Sinus Congestion or Sinus Pressure conditions may be appropriate.

Dosage and Usage

Follow the product label. Adults and children 12 years and older typically take 1 to 2 caplets with water every 4 to 6 hours as needed. Do not exceed the labeled maximum number of caplets in 24 hours. Swallow whole; do not crush or chew. Take with food or milk if stomach upset occurs. Do not use with other NSAIDs or other decongestants unless a clinician advises.

Each caplet is formulated as pseudoephedrine 30 mg ibuprofen 200 mg tablets. Do not use for more than 3 days for fever or 5 days for pain unless directed by a healthcare professional.

Strengths and Forms

Available as film-coated caplets combining pseudoephedrine hydrochloride and ibuprofen. Commonly published strength is 30 mg pseudoephedrine with 200 mg ibuprofen per caplet. Pack sizes vary by supplier and availability.

Many packs include Sudafed Sinus Advance 20 caplets, though local stock may differ. Availability can change without notice.

Missed Dose and Timing

This product is used as needed for symptoms, not on a fixed schedule. If it has been several hours and symptoms return, you may take the next dose per the label. Keep at least the labeled interval between doses. Do not double up to make up for a missed dose. Because pseudoephedrine may cause restlessness, avoid dosing close to bedtime if it affects sleep.

Storage and Travel Basics

Store in a cool, dry place at typical room conditions. Keep in the original packaging, tightly closed, and out of reach of children. Protect from excessive heat and moisture. When you travel, pack it in your carry-on and bring the box or leaflet to show ingredients to security or customs if asked. Some regions have limits on decongestants; confirm local rules before you travel. Our partners use temperature-controlled handling when required.

For broader cold and flu symptom options, see Cold Symptoms on our site.

Benefits

This combination offers two actions in one caplet. It may:

• Reduce sinus pressure
• Open nasal passages
• Relieve headaches
• Ease facial pain
• Lower fever
• Simplify dosing during colds

Side Effects and Safety

Common effects can include nausea, heartburn, stomach pain, dizziness, nervousness, insomnia, dry mouth, and a faster heartbeat. Many effects are mild and temporary.

Serious risks are uncommon but can occur. Ibuprofen may cause stomach bleeding, kidney problems, or, rarely, heart attack or stroke with higher doses or longer use. Pseudoephedrine may raise blood pressure or worsen some heart conditions. Stop use and seek care for allergic reactions, black or bloody stools, chest pain, severe dizziness, shortness of breath, or trouble urinating. For headache education, see Migraine And Headache Awareness.

Drug Interactions and Cautions

Do not use with or within 14 days of an MAOI. Ask a clinician before using with anticoagulants such as warfarin, antiplatelets, SSRIs/SNRIs, lithium, methotrexate, other NSAIDs or aspirin, or blood pressure medicines like ACE inhibitors or diuretics. Avoid combining with other decongestants or stimulant products. Limit alcohol to reduce stomach irritation risk. If pregnant or breastfeeding, seek medical advice before use; NSAIDs are generally avoided late in pregnancy.

What to Expect Over Time

After dosing, nasal airflow may improve as congestion eases and pain reduces. Some people may feel alert or restless due to the decongestant. If symptoms persist, worsen, or recur frequently, discuss evaluation for underlying conditions or alternate therapies with a clinician. For additional context on headaches, see Hypoglycemia Headaches.

Compare With Alternatives

Other options may suit different needs. For a similar decongestant-pain reliever profile, your prescriber may suggest generic pseudoephedrine ibuprofen tablets. If you prefer a nasal steroid for allergic swelling, consider Nasonex Aqueous Nasal Spray. For multi-symptom cold relief, see Sudafed Head Cold Sinus. Always compare active ingredients to avoid duplication.

Pricing and Access

We list Canadian pricing with US delivery from Canada for transparent access. Check live availability by pack size and quantity. For some shoppers, pseudoephedrine ibuprofen 30/200 mg price can be lower than local retail, depending on configuration and market conditions. If paying cash, review any available site offers; we update deals periodically.

Looking for current deals? See our promotions page: Promotions. You can view options, add items to your cart, and continue to checkout when ready.

Availability and Substitutions

Stock can vary by pharmacy and distributor. If an item is unavailable, your prescriber may recommend a suitable alternative with comparable ingredients or a different class, such as a nasal corticosteroid or an antihistamine-decongestant combination. We do not promise specific restock dates; check back for current status or consult a clinician about alternatives.

Patient Suitability and Cost-Saving Tips

This treatment may suit adults and adolescents seeking targeted sinus relief who can safely use NSAIDs and decongestants. It may not be appropriate for people with significant cardiovascular, renal, gastrointestinal, or thyroid conditions unless a clinician advises. If you are sensitive to stimulants, watch for sleep disruption and schedule doses earlier in the day.

To manage costs, consider larger pack sizes when appropriate to reduce per-caplet expense. Align your refill reminders with seasonal triggers, such as peak allergy months. Keep a small supply for travel, stored safely and out of children’s reach. Use one product at a time to avoid ingredient overlap and unnecessary spending.

Questions to Ask Your Clinician

• Is this combination appropriate with my health conditions?
• How long should I use it before reassessment?
• Which medicines or supplements should I avoid with it?
• Could a nasal steroid or antihistamine be a better option for me?
• What signs of stomach or heart-related side effects should I watch for?
• How should I manage nighttime symptoms if it disrupts sleep?
• If my blood pressure is elevated, is there a safer alternative?

Authoritative Sources

DailyMed: Ibuprofen and PseudoephedrineHealth Canada DPD: Pseudoephedrine + IbuprofenSudafed Canada

Ready to proceed? Add to cart to begin checkout and choose express shipping. Content here is informational and not a substitute for professional medical advice; always follow the label and your clinician’s guidance.