Kerendia® Tablets for Chronic Kidney Disease in Type 2 Diabetes

Kerendia® (finerenone) is an oral prescription medicine for adults with chronic kidney disease associated with type 2 diabetes. CanadianInsulin offers Canadian pricing and ships from Canada to the US with prompt, express shipping. This page explains approved uses, dosing, safety, and typical cash pay options for patients without insurance.

Qué es Kerendia® y cómo funciona

Every CanadianInsulin order is prescription-checked with your clinic and dispensed by a licensed Canadian pharmacy. Orders are filled in Canada and delivered to the US.

Kerendia® is a nonsteroidal mineralocorticoid receptor antagonist. It blocks overactivation of mineralocorticoid receptors in the kidneys and heart. This action helps reduce inflammation and fibrosis that can worsen kidney function and cardiovascular health.

Kerendia is FDA-approved to reduce the risk of sustained decline in kidney function, end-stage kidney disease, cardiovascular death, non-fatal heart attack, and hospitalization for heart failure in adults with chronic kidney disease associated with type 2 diabetes. It is usually added to a background ACE inhibitor or ARB that is already optimized.

Learn more in our overview article, How Kerendia Uses.

Para quién es Kerendia

Kerendia is for adults with chronic kidney disease linked to type 2 diabetes, often with albuminuria, who are already managed on an ACE inhibitor or an ARB. Clinicians consider it to further lower risks of kidney function decline and cardiovascular events.

Do not initiate if serum potassium is above 5.0 mEq/L. Starting treatment is not recommended when eGFR is below 25 mL/min/1.73 m2. Use is not recommended in severe hepatic impairment. Safety and effectiveness in pediatric patients have not been established.

For a wider view of therapies for kidney protection, see our Enfermedad renal crónica categoría.

Posología y utilización

Kerendia is taken once daily, with or without food. Swallow tablets whole.

• Check serum potassium and eGFR before starting.
• Starting dose by eGFR: eGFR ≥60 mL/min/1.73 m2: 20 mg once daily; eGFR 25 to <60: 10 mg once daily; eGFR <25: do not initiate.
• Do not initiate if serum potassium >5.0 mEq/L; consider closer monitoring if 4.8 to 5.0.
• Recheck potassium about 4 weeks after starting and after any dose change.
• Titration: if potassium ≤4.8 mEq/L and eGFR is stable at 4 weeks, increase to 20 mg once daily. If potassium rises >5.5 mEq/L, withhold; consider restarting at 10 mg once daily when potassium returns to ≤5.0.

Follow the prescribing information and clinician guidance for ongoing potassium and kidney function monitoring.

Fortalezas y formas

• Comprimidos: 10 mg
• Comprimidos: 20 mg
• Common pack sizes may include 30 and 90 tablets. Availability can vary.

Dosis omitida y momento oportuno

If a dose is missed, take it when remembered on the same day. If it is almost time for the next dose, skip the missed dose. Do not take two doses on the same day.

Almacenamiento y viaje

Store Kerendia tablets at room temperature, generally 20 to 25°C (68 to 77°F). Keep the bottle tightly closed and protect from moisture. Keep out of reach of children and pets. When traveling, carry your medicine in the original labeled container in your hand luggage.

Beneficios

• Reduces the risk of sustained eGFR decline and end-stage kidney disease in adults with diabetic kidney disease.
• Reduces the risk of cardiovascular death, non-fatal heart attack, and hospitalization for heart failure.
• Oral, once-daily dosing that fits routine care alongside ACE inhibitor or ARB therapy.
• Designed as a selective, nonsteroidal blocker of the mineralocorticoid receptor.

Many treatment plans may also include glucose-lowering and cardio-renal protective therapies. For a related option often used in type 2 diabetes with kidney disease, see our article Jardiance Kidney Disease.

Efectos secundarios y seguridad

• Common: increased potassium (hyperkalemia).
• Other reported: low blood pressure, dizziness, or low sodium.
• Laboratory changes in kidney function may occur, usually monitored with routine blood tests.

Serious risks include clinically significant hyperkalemia. Clinicians may pause treatment and address contributing factors if potassium rises too high. Allergic reactions are uncommon but possible. Patients with reduced kidney function, those on potassium supplements, or those taking other potassium-raising drugs have a higher risk of hyperkalemia.

Interacciones medicamentosas y precauciones

• Strong CYP3A4 inhibitors: contraindicated. Examples include ketoconazole, itraconazole, and clarithromycin.
• Strong or moderate CYP3A4 inducers: avoid. Examples include rifampin, carbamazepine, phenytoin, and St. John’s wort.
• Grapefruit or grapefruit juice: avoid due to increased exposure.
• Drugs that raise potassium: use caution with potassium supplements, potassium-sparing diuretics, salt substitutes with potassium, or other MRAs.
• Severe hepatic impairment: use not recommended.
• Pregnancy and breastfeeding: discuss risks and benefits with a clinician.

Qué esperar con el tiempo

Kerendia works over time to help reduce risks of kidney function decline and cardiovascular events. Regular blood tests track potassium and kidney function, especially after starting or changing dose. Kidney disease progression varies, so clinicians adjust therapy based on labs and overall risk factors, including blood pressure, albuminuria, and glucose control. For background on how diabetes affects the kidneys, see Diabetes y daño renal.

Comparar con alternativas

ACE inhibitors and ARBs remain foundational for albuminuric chronic kidney disease in type 2 diabetes. Kerendia is added when appropriate to further reduce kidney and cardiovascular risk. Prescribers may also choose a specific ACE inhibitor or ARB based on blood pressure, tolerability, and kidney goals. Examples we carry include Lisinopril and the ARB combination Irbesartán Htc. Therapy choices are individualized and follow official labeling and guidelines.

Precios y acceso

CanadianInsulin provides Canadian pricing with US delivery from Canada. Start your order to see current Kerendia price by strength and pack size. Many patients compare Kerendia cost with their local pharmacy, then choose cross-border options for value.

Patients often review Kerendia 10 mg price and Kerendia 20 mg price side by side. This helps estimate a Kerendia cash price for self pay. Some compare Kerendia price without insurance to an out of pocket cost under a high deductible plan. Others review a Kerendia tablet price by 30 or 90 count to plan monthly budgets. Searches such as cost of Kerendia, price of Kerendia, Kerendia price from Canada, and Kerendia price ships to US reflect common questions. Finerenone price references may also appear on statements or benefit summaries.

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Disponibilidad y sustituciones

Availability can vary by strength and pack size. If Kerendia is not available, a prescriber may suggest an appropriate alternative based on the treatment plan and labeling. Pharmacists may contact the clinic for guidance when needed.

Adecuación al paciente y consejos para ahorrar costes

• Potential candidates: adults with chronic kidney disease associated with type 2 diabetes, usually already on an ACE inhibitor or ARB, and appropriate potassium levels.
• Those who should avoid starting: serum potassium above 5.0 mEq/L or eGFR below 25 mL/min/1.73 m2, or severe hepatic impairment.
• Discuss all medicines and supplements that can raise potassium before starting.
• Consider 90-day fills to reduce per-tablet cost and simplify refills.
• Set refill reminders so your supply stays consistent.
• Lifestyle measures for blood pressure, glucose, and albuminuria complement medicine. For more, see Diabetes e hipertensión.

Preguntas para su médico

• Is Kerendia appropriate with my current ACE inhibitor or ARB dose?
• How often will potassium and kidney function be checked?
• What signs of high potassium should I watch for between labs?
• Should I avoid salt substitutes or potassium-containing supplements?
• Are there medicines I should stop or change before starting finerenone?
• Would a 90-day supply fit my plan and reduce my overall cost?
• Do I also need an SGLT2 inhibitor or other therapies for kidney and heart protection?

Fuentes autorizadas

• Bayer Kerendia Patient Site
• Información de prescripción de la FDA
• Base de datos de medicamentos de Health Canada

Start your Kerendia request today with US delivery from Canada.