Nifedipine XR Tablets for Hypertension

What Nifedipine XR Is and How It Works

This extended-release calcium channel blocker helps lower high blood pressure and reduce episodes of chest pain. It is available through CanadianInsulin with US delivery from Canada. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order. You can compare options without insurance before placing an order.

Nifedipine XR® belongs to the dihydropyridine class. It blocks L-type calcium channels in vascular smooth muscle, which relaxes arteries and lowers peripheral resistance. The once-daily matrix releases medicine over 24 hours to help stabilize blood pressure. For related therapies and background on the condition, see our Hypertension section.

Who It’s For

This medicine is indicated to manage hypertension and to treat chronic stable or vasospastic angina. It may be used as monotherapy or combined with other antihypertensives when appropriate. Patients needing long-acting control often benefit from a sustained formulation.

People with hypersensitivity to the drug should not take it. Those with severe aortic stenosis, very low blood pressure, or cardiogenic shock must avoid it. If your clinician recommends nifedipine extended-release, they will consider your cardiac history, current medications, and liver function.

Immediate-release forms are not appropriate for rapid blood pressure reduction in emergencies. Discuss prior heart attack, worsening angina, or edema with your prescriber before starting therapy. For chest pain topics and related medicines, visit our Angina page.

Dosage and Usage

Follow the exact instructions on your prescription label. Tablets are typically taken once daily at the same time. Swallow whole with water; do not split, crush, or chew. Consistency with meals matters; take it in a consistent manner relative to food, as directed on your product label. Avoid grapefruit and grapefruit juice, which can raise drug levels.

Commonly dispensed strengths include nifedipine xr 30 mg, 60 mg, and 90 mg, allowing individualized titration by your prescriber. Do not change your dose or schedule on your own. If you are switching from an immediate-release product, your clinician will set an appropriate regimen. Keep a record of home blood pressure readings and share them during follow-up.

If dizziness occurs, stand up slowly from sitting or lying positions. Alcohol can potentiate blood pressure lowering, so use caution. If you miss more than one dose, contact your prescriber for guidance rather than trying to catch up.

Strengths and Forms

This treatment is supplied as extended-release oral tablets in 30 mg, 60 mg, and 90 mg. Release characteristics are designed for 24-hour coverage when used as directed. Availability can vary by manufacturer and pharmacy.

Ask your clinician or pharmacist which formulation suits your needs. Some products recommend consistent timing relative to meals, while others do not. When in doubt, follow the label that comes with your prescription. Many patients use nifedipine xr tablets alongside other blood pressure therapies to reach targets.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember the same day. If it is close to your next dose, skip the missed dose and resume your regular schedule. Do not double up. Try setting a daily reminder or linking the dose to a routine activity, such as brushing your teeth.

Consistency supports steady 24-hour control. If timing changes are needed because of shift work or travel, ask your prescriber for advice before adjusting your schedule.

Storage and Travel Basics

Store tablets at room temperature in the original container, protected from moisture and excess heat. Keep the bottle tightly closed and out of reach of children and pets. Do not transfer tablets to non-child-resistant containers.

For travel, carry your medication in your hand luggage in the labeled pharmacy container. Pack enough for the entire trip plus a few extra days in case of delays. Bring a copy of your prescription and your prescriber’s contact information, which can help at security checkpoints or if you need a local refill. Avoid leaving tablets in a hot car or direct sunlight.

If crossing borders, keep medications in original packaging to avoid confusion. A written medication list is also helpful in emergencies. If your clinician has you on multiple cardiac medicines, consider a pill organizer that separates days and times to reduce missed doses.

Benefits

This extended-release calcium channel blocker provides 24-hour arterial relaxation, supporting smoother blood pressure control throughout the day. Once-daily dosing simplifies routines compared with multiple daily doses. For patients with angina, it may reduce the frequency of exertional chest discomfort.

As part of a comprehensive plan, it can be combined with lifestyle changes and other drug classes when clinically appropriate. Fewer peak-and-trough swings compared to immediate-release forms can help with tolerability for some patients.

Side Effects and Safety

• Headache: often occurs early and may lessen over time
• Flushing or warmth: related to vasodilation
• Dizziness or lightheadedness: especially when standing up quickly
• Peripheral edema: swelling of ankles or feet
• Fatigue: mild tiredness can occur
• Nausea or stomach discomfort: usually transient
• Palpitations: a sense of fast heartbeat in some patients

Serious but less common risks include pronounced hypotension, worsening angina, or rare myocardial infarction in susceptible patients with severe coronary artery disease. Gingival hyperplasia (gum overgrowth) can occur with chronic use. Seek urgent care for chest pain that is severe, persistent, or different from usual. Report significant swelling, shortness of breath, or fainting to your clinician.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors can raise levels and may increase side effects. Examples include ketoconazole, clarithromycin, and certain HIV protease inhibitors. CYP3A4 inducers such as rifampin, carbamazepine, phenytoin, and St. John’s wort can reduce effectiveness. Grapefruit and grapefruit juice should be avoided.

Use caution when combined with other blood pressure medicines, as additive effects can occur. Monitor carefully if taking beta-blockers, diuretics, ACE inhibitors, ARBs, or nitrates. Patients with hepatic impairment may require adjustments per the prescriber. Those with severe aortic stenosis, recent heart attack, or unstable angina need careful evaluation before initiation.

What to Expect Over Time

Blood pressure may trend downward over days to weeks with regular use. Some people feel no symptoms, which is normal; rely on home measurements and clinic checks to track progress. Headache or flushing may be most noticeable at the start and often improve with continued use.

Do not stop the medicine abruptly unless your prescriber instructs you to do so. Keep a log of readings, side effects, and missed doses to discuss at follow-up visits. If treatment goals are not met, your clinician may adjust therapy or combine it with other agents.

Compare With Alternatives

Another long-acting calcium channel blocker option is diltiazem in a controlled delivery form; discuss whether Diltiazem Hcl Cd might fit your profile. If a dihydropyridine alternative is preferred, amlodipine is widely used; you can review Norvasc with your prescriber. Each option has distinct profiles, and your clinician can help align therapy with your goals and comorbidities.

Pricing and Access

We list transparent options so you can review the nifedipine xr price and select quantities that fit your prescription. Canadian pricing with US shipping can provide savings compared with many local cash-pay options. If you purchase without insurance, review your order details carefully before checkout.

For occasional discounts on select items, see our Promotions page. Use the product selector to choose strength, quantity, and manufacturer when available. Secure, encrypted checkout protects your information throughout the process.

Availability and Substitutions

Supply can vary by strength and manufacturer. If your preferred option is unavailable, your prescriber may recommend an equivalent extended-release formulation or a different class. Do not substitute products on your own; forms can differ in release profile and dosing.

If a change is needed, your clinician will provide a new prescription that aligns with your treatment plan. Pharmacists can also help verify whether your formulation matches your prior fill.

Patient Suitability and Cost-Saving Tips

This therapy may be suitable for adults with hypertension or chronic stable angina who need once-daily management. It may not be appropriate for people with severe aortic stenosis, very low baseline blood pressure, or recent decompensated heart failure. Discuss all current medications, including over-the-counter products and supplements, with your clinician.

To lower overall costs, ask your prescriber about multi-month supplies when clinically appropriate. Set refill reminders so you do not run out. Keeping dose and strength stable can also help with continuity of supply. If multiple strengths are prescribed during titration, confirm quantities to avoid waste.

Questions to Ask Your Clinician

• Treatment goal: What blood pressure range should I aim for?
• Dose plan: How long should I stay at my current strength?
• Food effects: Should I take it with or without food consistently?
• Interactions: Which medicines or supplements should I avoid?
• Side effects: What symptoms mean I should call the clinic?
• Monitoring: How often should I check home readings?
• Travel: How should I handle time zone changes?

Authoritative Sources

For official U.S. labeling, consult the FDA DailyMed entry for nifedipine extended-release; see the product information at FDA DailyMed official database for drug labeling.

For Canadian product monographs and listings, review Health Canada’s Drug Product Database at Health Canada Drug Product Database entry page.

Some extended-release products are marketed by different manufacturers; see manufacturer prescribing information for detailed instructions at FDA Drug Approval database search portal.

Order from CanadianInsulin with prompt, express shipping with temperature-controlled handling when required. Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.