Nifedipine Tablets for Hypertension and Angina

Nifedipine is a calcium channel blocker for high blood pressure and chest pain. It lowers blood pressure and reduces angina by relaxing blood vessels. You can order the drug nifedipine with US delivery from Canada, which can help if you are paying without insurance.

What Nifedipine Is and How It Works

Nifedipine® is a dihydropyridine calcium channel blocker. It inhibits L-type calcium influx in vascular smooth muscle, leading to arterial vasodilation and reduced afterload. This class effect can lower blood pressure and lessen the frequency of angina episodes. Extended-release versions provide steadier exposure to limit rapid blood pressure drops.

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

Oral nifedipine is available as immediate-release and extended-release formulations. Immediate-release is generally reserved for angina; extended-release is widely used for hypertension. This medicine is part of cardiovascular therapy strategies that may combine lifestyle changes and other agents. For more on heart medicines and conditions, see our Cardiovascular category.

Who It’s For

This treatment is indicated for adults with hypertension and for chronic stable or vasospastic angina. It may be used alone or with other antihypertensives, based on clinical judgment. People who need emergency blood pressure reduction require different care and settings.

Do not use in patients with known hypersensitivity to the drug. Avoid use in cardiogenic shock. Use caution with severe aortic stenosis, recent myocardial infarction, heart failure, or significant hypotension. Discuss use during pregnancy or breastfeeding with a clinician. If your prescriber determines prescription nifedipine is appropriate, therapy will be tailored to your needs. Learn more about related conditions in Hypertension and Angina. For cold-induced digital symptoms, see Raynaud Phenomenon.

Dosage and Usage

Follow the Patient Information and your prescriber’s directions. Extended-release tablets are typically taken once daily at the same time, with or without food. Swallow tablets whole with water. Do not break, crush, or chew.

Some extended-release tablets use a nifedipine osmotic delivery system that leaves an inert tablet shell in stool; this is expected. Immediate-release forms may be dosed several times daily for angina when prescribed. Do not alter your regimen without consulting your prescriber.

Avoid grapefruit and grapefruit juice, which can increase drug exposure. If your plan includes an extended-release formulation, see Extended-Release Nifedipine for product specifics approved by your prescriber.

Strengths and Forms

Availability may vary by manufacturer and pharmacy. Common presentations include:

• Extended-release tablets (24-hour): 30 mg, 60 mg, 90 mg
• Immediate-release formulations for angina, per label

Package sizes and manufacturers can differ. Your prescriber will specify the appropriate formulation and strength on the prescription.

Missed Dose and Timing

If you miss a dose of rx nifedipine, take it when remembered unless it is close to the next dose. If the next dose is near, skip the missed dose and resume the regular schedule. Do not double up. If you miss doses often, speak with your care team about reminders or simpler schedules.

Storage and Travel Basics

Store tablets at room temperature in a dry place away from excess heat and light. Keep in the original, child-resistant container with the pharmacy label. Do not store in bathrooms or glove compartments.

When traveling, keep medicine in your carry-on bag with your prescription label and a copy of your prescription. Use a pill organizer if advised, but retain the labeled container for security checks. Plan dosing times across time zones in advance and confirm with your prescriber if needed. For broader context on managing conditions that often co-exist, see Diabetes and Hypertension.

Benefits

This class can reduce blood pressure and help prevent angina episodes when taken as prescribed. Extended-release options support once-daily routines, which may aid adherence. It can be combined with other agents when clinically appropriate.

Side Effects and Safety

• Headache or flushing
• Dizziness or lightheadedness
• Peripheral edema (swelling of ankles or feet)
• Fatigue or weakness
• Nausea, heartburn, or constipation
• Palpitations

Serious or rare effects can include marked hypotension, worsening angina on initiation or dose increase, syncope, and hepatic enzyme elevations. Contact a clinician promptly for severe chest pain, shortness of breath, fainting, or allergic reactions. When used with other blood pressure medicines, additive effects may occur. For additional reading about beta-blocker options sometimes used in combination strategies, see our overview on Bystolic Guide.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors (for example, certain azole antifungals, macrolide antibiotics, and some HIV protease inhibitors) can raise levels and increase adverse effects. Strong CYP3A4 inducers (for example, rifampin, carbamazepine, phenytoin, and St. John’s wort) can reduce effectiveness. Avoid grapefruit or grapefruit juice. Monitor when combined with beta-blockers or other antihypertensives due to additive blood pressure lowering.

Digoxin concentrations may change; your prescriber may monitor levels. Use caution with severe hepatic impairment. If you are considering other options in the same therapeutic area, our detailed resource on beta-blockers is a helpful complement: Atenolol Guide. You can also explore ACE inhibitors in our article Altace Guide.

What to Expect Over Time

Blood pressure improvements are generally assessed over days to weeks with consistent use, while angina frequency can change as your regimen stabilizes. Your clinician may check response and tolerability at follow-up visits. Consistent daily timing and avoidance of missed doses can support stable control.

Keep a log of home blood pressure readings if advised. Note any swelling, headaches, or dizziness and share these observations at appointments. Do not stop therapy abruptly without medical guidance.

Compare With Alternatives

Other calcium channel blockers may be considered based on your profile. Amlodipine is a once-daily dihydropyridine commonly used for similar indications; see Norvasc®. A non-dihydropyridine option that slows heart rate may suit some angina cases; consider Diltiazem HCl CD after discussing with your prescriber. Verapamil is another alternative selected in specific scenarios.

Pricing and Access

We list current options so you can compare formulations and manufacturers. Canadian pricing can offer value for many US customers. If you are exploring affordability, you can review nifedipine price details on the product page.

Check the price of nifedipine and consider multi-month fills if appropriate. We also provide periodic offers; see our Promotions page for current information. Orders are processed through encrypted checkout. We provide US shipping from Canada to eligible addresses when your prescription is verified.

Availability and Substitutions

Manufacturers and pack sizes can vary over time. If a specific strength or brand is unavailable, your prescriber may recommend a therapeutically appropriate alternative. We cannot promise restock dates but will display current items when available.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults who need a calcium channel blocker for blood pressure or angina control. It may not be appropriate for those with very low blood pressure, cardiogenic shock, or specific structural heart conditions. Discuss your medical history and all medicines you take with your clinician.

To manage costs, ask your prescriber about longer fills if stable on therapy. Setting refill reminders can help prevent lapses. Consolidate orders to reduce per-order fees when practical. If you are paying without insurance, compare options across strengths and manufacturers as advised by your prescriber.

Questions to Ask Your Clinician

• Primary goal: blood pressure, angina, or both?
• Which formulation suits my regimen?
• How should I time doses with meals?
• What side effects should I watch for?
• Any interactions with my current medicines?
• Is grapefruit avoidance necessary for me?
• When should I schedule follow-up checks?

Authoritative Sources

For full prescribing information and patient guides, see FDA DailyMed; the monograph for extended-release tablets provides labeled indications and safety details: FDA DailyMed main site for drug labeling.

Health Canada’s Drug Product Database lists approved products and manufacturers; consult the entry for current Canadian status: Health Canada Drug Product Database lookup.

For branded reference information on a nifedipine product line, the manufacturer hosts official resources you can review with your clinician: Bayer corporate information portal.

Order at CanadianInsulin for convenient checkout, prompt, express shipping and temperature-controlled handling when required.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.