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Januvia

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Description

What is Januvia (Sitagliptin)?

Januvia is a once-a-day prescription drug that, alongside a healthy diet and regular exercise, helps to lower blood sugar in adults that have type 2 diabetes. Its chemical, or generic name is Sitagliptin. Your doctor may refer to Januvia as Sitagliptin, Januvia’s generic name.

What is it used for?

Januvia is used for the treatment of type 2 diabetes, but not type 1 diabetes. It is prescribed either alone or in combination with other oral antidiabetic drugs in order to help improve blood sugar levels.

How does this medication work?

Januvia is a member of a group of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It works by blocking enzymes that breakdown important hormones involved in eating, appetite and digestion. These hormones play a large role in regulating blood sugar levels. When the breakdown of these hormones is blocked it allows the pancreas to increase the amount of insulin production, and also decrease the amount of glucagon production, which normally increases your blood sugar levels. As your blood sugar levels begin returning to normal, the effects on of insulin and glucagon slowly diminishes, which prevents an “overshoot” that can lead to low blood sugar (hypoglycemia) which is often seen with other oral antidiabetic drugs.

How to take Januvia (Sitagliptin)

Januvia should be taken once daily, as your doctor tells you. You may take your medicine with or without food. You might also be required by your doctor to do blood tests from time to time to see how your kidneys are working. Your dose may be changed by your doctor based on the results of your blood tests. Your doctor might also ask you to take it along with other diabetes medicines. Hypoglycemia or low blood sugar can occur more often when it is used with certain other diabetes medicines.If you should happen to miss a dosage, make sure that you take it as soon as you can. If you don’t remember until it is almost time for your next dosage, skip that missed dose and go back to your regular schedule. Never take two doses at the same time to make up for any missed doses.

Januvia Dosage

The recommended dose of is 100 mg once daily, and can be taken with or without food.For patients with mild kidney insufficiency no dosage adjustment for is required. For patients with moderate kidney insufficiency the dose is lowered to 50 mg once daily. For patients with severe kidney insufficiency or with end-stage renal disease (ESRD) which requires hemodialysis or peritoneal dialysis, the dose lowered to 25 mg once daily. It may be administered without regard to the timing of dialysis.When it is used in combination with insulin, or an insulin secretagogue (e.g., sulfonylurea), a smaller dose of insulin or the insulin secretagogue might be required to reduce the risk of low blood sugar (hypoglycemia).

Warnings and Precautions

As with most drugs prescribed for the treatment of diabetes, Januvia should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (increased ketones in the urine or blood). You should not use it if you are allergic to sitagliptin.Cases of pancreatitis (inflammation of the pancreas) which may be severe and lead to death have been reported in some patients. Cases of a skin condition called bullous pemphigoid that may require hospital treatment have also been reported in some people. Tell your doctor immediately if you develop blisters or have any breakdown of your skin.

To make sure it is safe for you, tell your doctor if you have:

  • pancreatitis
  • kidney disease (or if you are on dialysis)
  • gallstones
  • high triglycerides (a type of fat in the blood)
  • a history of alcoholism

Januvia Side Effects

Common negative effects may include:

  • stuffy or runny nose
  • sore throat

Less common negative effects may include:

  • allergic reactions, including hives, rash, and swelling of the tongue, lips, face, and throat which may cause problems with swallowing or breathing
  • inflammation of the pancreas
  • kidney complications (sometimes requiring dialysis)
  • vomiting
  • headache
  • constipation
  • joint pain
  • muscle aches
  • back pain
  • arm or leg pain
  • itching
  • blisters

Rare negative effects may include:

  • Pancreatitis. Symptoms include prolonged severe abdominal pain that may be accompanied by vomiting
  • Bullous pemphigoid (blisters or a breakdown of your skin)
  • Acute kidney failure. Symptoms may include loss of appetite and weakness, nausea, breathlessness, and passing little or no urine.
Tell your doctor immediately if you develop any unusual side effects, or any of the above side effects that get worse or do not go away.
Januvia 5 stars 1 reviews.
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    A Canadianinsulin.com Customer
    AC
    05/28/2024
    Anthony C.
    US US

    Great Service

    Very good. No problems during ordering or shipment. Medication received in a timely manner.

    05/28/2024

    Canadianinsulin.com

    Hi Anthony,Thank you for your positive feedback! We're glad to hear that you had no issues with your order or shipment and received your medication promptly. If you have any questions or need further assistance, please don't hesitate to reach out. We're here to support you.Thank you for choosing Canadian Insulin. Have a great day!

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    The Brand

    About

    Januvia
    Januvia, scientifically known as Sitagliptin, is an oral diabetes medication produced by the pharmaceutical giant Merck Co., Inc. This brand specifically contributes to the control of high blood sugar levels deplorably prevalent in patients with type 2 diabetes. Its primary objective is to regulate the levels of insulin the body produces after eating. Januvia works by increasing substances in the body that lower blood sugar. Used in conjunction with a healthy diet and plenty of exercise, Januvia significantly aids in controlling blood sugar levels. However, it's important to note that this brand is not for treating type 1 diabetes. Januvia exemplifies a robust response in the battle against diabetes, significantly improving the lives of those affected by this condition. Recognizing its potential, Canadian Insulin, an online pharmaceutical provider, has it available for purchase. This reputable provider is known for their dedication in offering a wide variety of insulin and diabetes medications at affordable prices, further cementing their commitment to the health of their customers. Whether it's Januvia or any other diabetes medication, Canadian Insulin is a reliable source, prioritizing the welfare of those living with diabetes.
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