Losartan Tablets for High Blood Pressure

This angiotensin receptor blocker treats high blood pressure and helps protect kidneys in type 2 diabetes. This page outlines labeled uses, dosing, safety, and access options with US delivery from Canada. You can also review typical pricing, including options without insurance.

What Losartan Is and How It Works

Cozaar® is the reference brand for losartan, an angiotensin II receptor blocker. It selectively blocks the AT1 receptor, reducing the action of angiotensin II. That relaxes blood vessels and lowers aldosterone effects. The result can be lower blood pressure and less kidney strain in susceptible patients.

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Losartan 50 mg oral tablet is a common adult strength. The agent may be taken with or without food. It acts within the renin-angiotensin-aldosterone system to reduce vasoconstriction and sodium reabsorption. Clinicians may consider this therapy when ACE inhibitors are not tolerated. Your prescriber will base selection on medical history, comorbidities, and prior response.

Who It’s For

For adults, this therapy treats hypertension to reduce cardiovascular risk. Losartan 50 mg for high blood pressure is a typical target strength for many patients, but dosing is individualized. It also treats diabetic nephropathy in type 2 diabetes with proteinuria and hypertension. In people with left ventricular hypertrophy, it reduces stroke risk in combination with blood pressure control.

Learn more about High Blood Pressure and Diabetic Nephropathy.

Dosage and Usage

Start and titration follow label guidance. Losartan 50 mg dosage is common once daily. Some patients start at 25 mg if volume depleted or with hepatic impairment. The usual range is 25 to 100 mg per day, given once or divided. Pediatric dosing (6 to 16 years) is weight based when used and supervised by a clinician. Take tablets at the same time daily, with or without food. Swallow whole with water and measure blood pressure as advised by your healthcare professional.

Strengths and Forms

This medicine is supplied as film-coated tablets. Available strengths commonly include 25 mg, 50 mg, and 100 mg. Many patients receive losartan 50mg tablets, while others use 100 mg tablets when indicated. Fixed-dose combinations with hydrochlorothiazide are available when a diuretic is needed, such as losartan HCTZ 50/12.5 mg or 100/25 mg. Availability can vary by manufacturer and lot.

Missed Dose and Timing

If you miss a dose, take it when remembered on the same day. If it is almost time for the next dose, skip the missed dose. Do not take two doses at the same time. Aim for a consistent schedule to support stable blood pressure control. Food does not significantly alter absorption for most patients.

Storage and Travel Basics

Store tablets at room temperature in a dry place and in the original container. Keep the bottle tightly closed and out of reach of children. Protect from moisture and excessive heat. When traveling, carry your medicine in hand luggage with the prescription label. Bring sufficient supply and a copy of your prescription if crossing borders. Maintain your once-daily routine across time zones to keep dosing consistent.

Benefits

This treatment lowers blood pressure and supports cardiovascular risk reduction when taken as prescribed. In type 2 diabetes with proteinuric kidney disease, it can slow the progression of nephropathy per approved labeling. Once-daily dosing supports adherence for many patients. It is often selected when cough or angioedema occurred with an ACE inhibitor, subject to clinician judgment.

Side Effects and Safety

• Dizziness or lightheadedness, especially after the first doses
• Nasal congestion or upper respiratory symptoms
• Back pain or muscle cramps
• Diarrhea or abdominal discomfort
• Fatigue

Serious but uncommon effects include symptomatic hypotension, kidney function changes, increased potassium, and angioedema. Fetal toxicity can occur; do not use during pregnancy. People who are volume- or salt-depleted may experience low blood pressure after starting. Those with renal artery stenosis may have increased risk of renal impairment. Seek urgent care for facial swelling, tongue or throat swelling, or trouble breathing.

Drug Interactions and Cautions

Use caution with potassium supplements, potassium-sparing diuretics, or salt substitutes that contain potassium. NSAIDs can lessen antihypertensive effects and may affect kidney function. Lithium levels may rise; monitoring is often recommended if used together. Avoid combining with another RAAS blocker (ACE inhibitors or aliskiren in diabetes) unless directed by a specialist. Moderate alcohol can add to blood pressure–lowering effects. People with advanced renal disease require close monitoring; see our Kidney Disease resource.

What to Expect Over Time

Blood pressure lowering builds with consistent daily use. Your prescriber may assess labs such as creatinine and potassium. Lifestyle steps like sodium reduction, weight management, and regular activity can enhance results. Bring a home blood pressure log to appointments for review. For broader education, see Diabetes And High Blood Pressure and Jardiance Kidney Disease.

Compare With Alternatives

Other angiotensin receptor blockers may be appropriate if a change is needed. Valsartan provides once-daily regimens with broad use. Telmisartan offers long-acting options in select patients. ACE inhibitors such as ramipril may be considered when clinically preferred. Selection depends on comorbidities, tolerance, and guideline recommendations.

Pricing and Access

You can review current pricing and submit your prescription for verification. Losartan 50 mg price without insurance varies by fill size and dispenser. Our site shows Canadian pricing for transparency with US delivery from Canada. If you have a coupon, visit our Promotions page. Checkout uses encrypted processing to protect your data. Your prescriber can send a prescription directly if required.

Availability and Substitutions

Supply may differ by strength and manufacturer. If a specific tablet is unavailable, a prescriber may suggest an appropriate alternative or a temporary substitution with a different strength to match the intended daily dose. Losartan 50 mg from Canada may be supplied by different labelers; generics must meet regulatory quality standards. Combination tablets with hydrochlorothiazide can be considered when an added diuretic is warranted.

Patient Suitability and Cost-Saving Tips

This therapy suits many adults with hypertension, including those with diabetic kidney disease. It should not be used during pregnancy. People with severe hepatic impairment or a history of angioedema with ARBs need careful evaluation. To manage costs, consider multi-month fills, use reminders for timely refills, and compare unit pricing across strengths. Ask your prescriber whether a combination tablet could replace separate medicines to simplify your regimen.

Questions to Ask Your Clinician

• What starting dose and blood pressure target are appropriate for me?
• How often should my kidney function and potassium be checked?
• Should I add a diuretic or switch to a combination tablet?
• What should I do if I feel dizzy or lightheaded after a dose?
• Is switching from an ACE inhibitor to this ARB appropriate for me?
• Can I use NSAIDs for pain while on this treatment?
• How should I handle travel and time-zone changes with once-daily dosing?
• Which symptoms require urgent medical attention?

Authoritative Sources

DailyMed: Losartan Potassium Monographs

Cozaar Prescribing Information (Merck)

Health Canada Drug Product Database

Ready to proceed? Place your order for prompt US delivery from Canada, with temperature-controlled handling when required. This information is educational and not a substitute for medical advice; always follow your prescriber’s directions.