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Rosuvastatin

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Description

Use of Rosuvastatin

Rosuvastatin is a medication used to lower high levels of cholesterol in the blood, reducing the risk of heart disease and stroke.

Mechanism of Action

Rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme involved in the production of cholesterol in the liver. By blocking this enzyme, it reduces the amount of cholesterol produced in the body and increases the liver’s ability to remove LDL cholesterol from the bloodstream.

Precautions and Warnings

  • Inform your healthcare provider about any liver disease or history of muscle disorders.
  • Avoid excessive alcohol consumption while taking rosuvastatin.
  • Use caution when taking certain medications that may interact with rosuvastatin, such as cyclosporine or gemfibrozil.
  • Pregnant or breastfeeding women should consult with their healthcare provider before using rosuvastatin.

Dosage

The typical starting dose of rosuvastatin is 10 mg once daily, with adjustments made based on individual patient response and cholesterol levels. It can be taken with or without food, preferably in the evening.

Side Effects

Common side effects of Rosuvastatin include the following:
  • Headache
  • Muscle pain
  • Weakness
  • Abdominal pain
  • Constipation
  • Nausea
  • Dizziness
  • Increased blood sugar levels (hyperglycemia)
  • Liver enzyme abnormalities
 

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The Brand
Rosuvastatin
Rosuvastatin, widely recognized under the brand name Crestor, is a leading medication for managing cholesterol levels and reducing the risk of cardiovascular events. Developed by AstraZeneca, Rosuvastatin is a powerful statin that works by inhibiting HMG-CoA reductase, an enzyme critical in the production of cholesterol in the liver. This action helps lower LDL cholesterol (often referred to as “bad” cholesterol) and triglycerides while increasing HDL cholesterol (“good” cholesterol). Rosuvastatin’s proven efficacy and robust safety profile have made it a trusted choice for patients with hyperlipidemia and those at high risk of heart disease. AstraZeneca’s commitment to innovation and patient-centered care ensures that Rosuvastatin provides effective, reliable treatment for maintaining cardiovascular health and preventing serious complications associated with high cholesterol.
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