Please note: a valid prescription is required for all prescription medication.
This extended-release calcium channel blocker treats high blood pressure. It can also help limit episodes of chronic stable angina. Available with US delivery from Canada, verapamil SR without insurance may lower out-of-pocket spend.
What Verapamil Is and How It Works
This medicine limits calcium entry into cardiac and vascular smooth muscle. That action relaxes arteries and lowers peripheral resistance. It can slow atrioventricular nodal conduction, which may modestly reduce resting pulse. The sustained-release design spreads absorption over many hours for steadier levels.
CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.
In clinical practice, verapamil HCl SR is classified as a non-dihydropyridine calcium channel blocker. It is intended for oral use and should be taken exactly as directed on the product label.
Who It’s For
This treatment is used in adults to manage hypertension. It may also reduce the frequency of exertional angina when prescribed for that purpose. People with second- or third-degree AV block, sick sinus syndrome without a pacemaker, severe hypotension, or advanced heart failure should not use it. Dose adjustments or closer monitoring may be needed in hepatic impairment or in older adults. Explore related options in Heart Health Medications, and broader condition resources in Hypertension Cardiovascular. If diabetes coexists, see Diabetes Cardiovascular Disease for risk education.
Dosage and Usage
Follow the product label approved for your prescription. Most extended-release tablets are taken once daily at the same time. Some brands are labeled for morning use, and others for bedtime dosing. Consistency matters more than clock time. Swallow tablets whole with water. Do not crush or chew. Take with or without food, but use the same approach each day to keep levels steady. Avoid grapefruit or grapefruit juice. If your prescriber combines therapies, take the other medicines at the times they recommend. Do not change your schedule without medical guidance.
Strengths and Forms
Availability may vary by manufacturer and pharmacy.
- Sustained-release tablets: 120 mg, 180 mg, 240 mg, 360 mg
- Sustained-release capsules: 120 mg, 180 mg, 240 mg, 360 mg
- Marketed brands in some regions: Securon SR, Vertab SR, Veracaps SR
Missed Dose and Timing
If you miss a dose, take it when remembered the same day. If it is close to the next scheduled dose, skip the missed dose and return to your usual time. Do not double up. Keep a daily reminder or use a smartphone alert to support adherence. If repeated doses are missed, speak with your prescriber about how to restart safely.
Storage and Travel Basics
Store at room temperature in a dry location. Keep the bottle tightly closed and protected from moisture and excess heat. Do not remove desiccants if present. Keep out of reach of children and pets. When traveling, carry your medicine in the original labeled container. Pack it in your carry-on to limit temperature swings and reduce loss risk. Bring a copy of your prescription or a pharmacy receipt, especially for international trips. Keep medicines separate from liquids and sharp items during security checks.
Benefits
- Once-daily schedule: Simplifies daily routines for many adults
- Steady control: Smooth 24-hour exposure with fewer level swings
- Blood pressure lowering: Helps reduce cardiovascular risk when combined with lifestyle
- Angina symptom support: May decrease exertional chest discomfort when prescribed
- Generic access: Broad availability that can support affordability
- Combination use: Often paired with thiazides or ACE inhibitors when needed
Side Effects and Safety
- Constipation
- Dizziness or lightheadedness
- Headache
- Tiredness
- Flushing
- Swelling of ankles or feet
- Nausea
- Gum overgrowth
Serious effects can include slow heart rate, new or worsening heart block, fainting, low blood pressure, or worsening heart failure. Rare liver injury or severe skin reactions have been reported. Seek urgent medical care for chest pain, syncope, breathing trouble, or signs of allergic reaction. Use with caution if you have conduction disease, bradycardia, or heart failure with reduced ejection fraction. Follow your prescriber’s monitoring plan.
Drug Interactions and Cautions
- Grapefruit products: Can raise levels
- Strong CYP3A4 inhibitors: Macrolides, azole antifungals, HIV protease inhibitors
- CYP3A4 inducers: Rifampin, carbamazepine, phenytoin, St. John’s wort
- Beta blockers: Additive effects on heart rate and AV conduction
- Digoxin: Levels may increase; monitoring is often advised
- Lithium: Neurotoxicity risk may rise
- Statins: Limit simvastatin dose; consider alternatives
- Alcohol: Can potentiate dizziness or hypotension
Discuss all medicines and supplements with your prescriber to avoid interactions. For background on statin therapy, see Lipitor Uses. If you take multiple heart medicines, your clinician may adjust timing to reduce overlap of peak effects.
What to Expect Over Time
Blood pressure lowering is gradual and depends on consistent use. You may see improvements on home readings and during clinic checks. Constipation can occur early and may improve with hydration and fiber intake. Do not stop abruptly, as discontinuation may increase angina risk. Your prescriber may monitor heart rate, conduction, and liver enzymes based on your history. For a perspective on another rate-controlling class, review Atenolol And Hypertension.
Compare With Alternatives
Therapy selection is individualized. Another non-dihydropyridine option is Diltiazem Hcl Cd, which also relaxes vessels and slows AV conduction. A dihydropyridine alternative is Nifedipine Xr, which primarily lowers peripheral resistance with minimal effect on heart rate. Your prescriber will match the class to your blood pressure pattern, heart rate, and comorbidities.
Pricing and Access
We list verapamil SR Canadian pricing so you can review options clearly. Orders Ships from Canada to US with licensed pharmacy dispensing. You can view current pricing and typical cash-pay savings after creating an account. Our encrypted checkout protects your information. To explore related items across conditions, browse Hypertension Cardiovascular.
Availability and Substitutions
Supply can vary by manufacturer. If a specific product is temporarily unavailable, a prescriber may allow a therapeutically equivalent fill. Check whether verapamil SR US shipping aligns with your travel or refill plans. If not suitable, your prescriber may recommend another calcium channel blocker.
Patient Suitability and Cost-Saving Tips
Good candidates include adults with essential hypertension who do not have advanced conduction disease or decompensated heart failure. The verapamil SR cash price can vary by manufacturer and quantity. To help manage out-of-pocket costs, consider:
- Multi-month fills: A 90-day supply when appropriate
- Consistent brand or manufacturer: Supports predictable response
- Aligned refills: Combine dates to reduce pharmacy trips
- Home BP logging: Share readings to support efficient adjustments
- Reminder tools: Set refill and dose alerts in your account
Ask your prescriber if a single daily dosing schedule fits your overall therapy plan. Report new swelling, dizziness, or slow pulse promptly.
Questions to Ask Your Clinician
- Is an extended-release schedule appropriate for my health history?
- Should I take the dose in the morning or at bedtime?
- What target blood pressure should I track at home?
- Which symptoms suggest dose changes or intolerance?
- How do my other medicines interact with this treatment?
- What labs or ECG checks will you monitor?
- How should I handle missed doses on travel days?
- What are safe options if constipation develops?
Authoritative Sources
Ready to proceed? You can place your request at CanadianInsulin with US shipping from Canada and express shipping with temperature-controlled handling when required. This information is educational and does not replace medical advice from your healthcare professional.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
What is the difference between immediate-release and sustained-release verapamil?
Immediate-release tablets are usually taken multiple times per day and can cause peaks and troughs in concentration. Sustained-release versions are designed for a slower, steadier release over many hours, allowing once-daily or sometimes twice-daily schedules per labeling. The goal is smoother blood pressure control and fewer dosing times. People with conduction disease or heart failure need individualized assessment before using either form. Follow the specific product label for timing and administration instructions.
Can I split or crush sustained-release tablets?
Do not crush or chew extended-release tablets, since altering the dosage form can release the medicine too quickly. Some capsule products may have distinct instructions, but many should also be swallowed whole. Always read the package insert that accompanies your prescription and follow your prescriber’s guidance. If you have difficulty swallowing tablets or capsules, ask about other available formulations or whether a different class could be appropriate.
How does this medicine affect heart rate?
This calcium channel blocker can slow conduction through the atrioventricular node and may reduce resting heart rate. The effect is typically modest at doses used for hypertension but can be more pronounced in sensitive individuals, those on beta blockers, or people with underlying conduction disease. Report new dizziness, near-fainting, or very slow pulse. Your clinician may monitor heart rate and, when appropriate, perform ECG checks during therapy.
Which foods, drinks, or medicines should I avoid?
Avoid grapefruit products because they can raise drug levels. Alcohol may increase dizziness or drop blood pressure. Certain antibiotics, antifungals, and HIV medicines inhibit CYP3A4 and can elevate exposure, while inducers like rifampin or St. John’s wort can lower it. Beta blockers, digoxin, lithium, and some statins need careful coordination. Provide a full medication list to your prescriber and pharmacist so they can review for interactions.
What should I do if I miss doses repeatedly?
If you miss a single dose, take it the same day when remembered unless it is near the next scheduled time. Skip rather than double up. Repeated omissions can affect blood pressure control. Use reminders, pill organizers, or synchronized refills to improve adherence. If missed doses occur often, contact your prescriber. They can advise on safe resumption and whether adjustments or additional monitoring are needed based on your blood pressure and heart rate.
Is it safe during pregnancy or breastfeeding?
Use during pregnancy or while breastfeeding should be guided by a risk–benefit assessment. Small amounts may pass into breast milk. If treatment is necessary, a clinician will weigh maternal benefits against potential infant risks and consider alternative therapies if appropriate. Share pregnancy plans or nursing status with your prescriber before starting therapy. They can coordinate monitoring and choose the most suitable regimen for your situation.
What monitoring might be needed while taking it?
Monitoring plans vary. Your prescriber may check blood pressure, resting heart rate, and, when indicated, an ECG for conduction changes. In some cases, liver function tests are considered. If you also take digoxin, levels may be monitored. Keep a home blood pressure log to share at visits. Report swelling, dizziness, slow pulse, or shortness of breath. These details help your clinician assess tolerability and overall treatment effect.
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