Verelan® (Verapamil SR) for Hypertension and Angina

Verapamil SR is the sustained-release form of verapamil used to lower blood pressure and prevent angina. This page helps you compare options, see forms and strengths, and learn safe use. We offer Canadian pricing with US delivery from Canada, so it ships to the US reliably. Many patients also pay cash without insurance.

CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order.

What Verapamil SR Is and How It Works

Verapamil is a calcium channel blocker. It relaxes blood vessels and reduces the workload on the heart. It slows conduction through the AV node, which can lower heart rate and help with certain arrhythmias. Brands such as Verelan® and Calan SR illustrate the sustained or extended-release designs that provide steady levels over the day.

Verapamil SR tablets or extended-release capsules are designed to be taken once daily in many cases. Some SR tablets may be twice daily depending on the specific product. The controlled release helps maintain blood pressure through 24 hours and can reduce angina episodes. It is not an emergency treatment for chest pain.

We ship from Canada to the US with transparent Canadian pricing. You can buy Verapamil SR online and have your prescription filled after clinic verification.

Who Verapamil SR Is For

Verapamil SR is used for:

• Hypertension in adults.
• Chronic stable or vasospastic angina.
• Rate control in certain supraventricular arrhythmias, when appropriate formulations are used.

It may not be suitable if you have severe left ventricular dysfunction, severe hypotension, sick sinus syndrome or second- or third-degree AV block without a pacemaker, or cardiogenic shock. People with heart failure should use caution and follow prescriber guidance. Discuss liver impairment, kidney issues, pregnancy, or breastfeeding with your clinician.

Dosage and Usage

Follow the exact regimen on your prescription label. Typical label-based guidance includes:

• Hypertension, SR tablets: common starting dose 120 mg to 180 mg once daily. Some patients start at 240 mg once daily depending on product and response.
• Titration: adjust in 1- to 2-week intervals based on blood pressure and tolerability.
• Maximum: many labels list up to 480 mg daily for hypertension. The exact ceiling depends on the specific SR or ER product used.
• Angina: total daily doses often range 240 mg to 480 mg using sustained- or extended-release formulations.

Swallow sustained- or extended-release tablets or capsules whole. Do not crush or chew. Some ER capsules can be opened and sprinkled per the specific label, but only if your product’s instructions allow it. Take consistently with regard to meals if directed by your product label.

If your prescriber switches you from immediate-release tablets to an SR or ER product, they will guide total daily dose equivalence and schedule. Never change dose or schedule on your own.

Strengths and Forms

Commonly available strengths include:

• Immediate-release tablets: 40 mg, 80 mg, 120 mg.
• Sustained-release tablets: 120 mg, 180 mg, 240 mg.
• Extended-release capsules: 100 mg, 120 mg, 180 mg, 200 mg, 240 mg, 300 mg, 360 mg.

Availability may vary by manufacturer and country. Your prescribed product may specify SR tablet or ER capsule with different dosing instructions.

Missed Dose and Timing

If you miss a once-daily dose, take it when remembered unless it is close to the next dose. If it is nearly time for your next scheduled dose, skip the missed dose. Do not double up. Keep a regular schedule for the best blood pressure control.

Storage and Travel Basics

Store Verapamil SR at room temperature, in a dry place, and in the original container. Protect from moisture. Keep out of reach of children. When traveling, carry your medicine in your hand luggage and keep it with the label. For US shipping from Canada, we pack orders securely for transit.

Benefits

• Helps reduce blood pressure and cardiovascular strain.
• Prevents angina episodes by improving oxygen supply-demand balance.
• Steady control with sustained- or extended-release formulations.
• Once-daily dosing convenience with many products.
• May help rate control for certain supraventricular arrhythmias when prescribed appropriately.

Side Effects and Safety

• Common: constipation, dizziness, headache, fatigue, nausea, flushing.
• Fluid-related: ankle or foot swelling.
• Heart-related: slow heart rate or low blood pressure.

Serious effects can include marked bradycardia, AV block, syncope, severe hypotension, or worsening heart failure. Rare events include liver enzyme elevations and allergic reactions. Seek urgent care for fainting, severe shortness of breath, or chest pain that is new or different. The risk of low blood pressure or bradycardia increases with other rate-slowing drugs such as beta blockers.

Drug Interactions and Cautions

Verapamil is metabolized by CYP3A4 and also inhibits CYP3A4 and P-gp. Important interactions include:

• Beta blockers (e.g., metoprolol, propranolol): higher risk of bradycardia or AV block.
• Digoxin: verapamil can increase digoxin levels.
• Statins metabolized by CYP3A4 (e.g., simvastatin): higher statin exposure; dose limits may apply.
• Antiarrhythmics and rate-slowing agents: additive effects are possible.
• Grapefruit or grapefruit juice: can raise verapamil levels.
• Carbamazepine, rifampin, and other enzyme inducers or inhibitors: may change verapamil exposure.

Limit alcohol. Use caution when driving until you know how the medicine affects you. Discuss all prescriptions, OTC medicines, and supplements with your clinician to avoid harmful combinations. For broader context on beta blocker therapy, you can review our article on Acebutolol Uses Benefits Dosage. For lipid management considerations that often accompany hypertension care, see Lipitor Uses How It Helps.

What to Expect Over Time

Blood pressure often improves within the first weeks, with additional benefit after dose adjustments. Angina frequency may decrease with consistent daily use. Arrhythmia-related benefits depend on the specific diagnosis and formulation. Your prescriber may adjust dose at 1- to 2-week intervals until goals are met. Keep follow-up appointments and track blood pressure at home if advised.

Compare With Alternatives

Other calcium channel blockers may be options if verapamil is not a fit. Amlodipine is a once-daily dihydropyridine CCB that lowers blood pressure and reduces angina frequency with minimal heart-rate effect. See Norvasc®. Diltiazem offers both rate control and vasodilating effects, with many controlled-delivery strengths; review Diltiazem Hcl Cd for another sustained-release option. Your prescriber will select based on your history, heart rate, and tolerability.

Pricing and Access

Take advantage of Canadian pricing on Verapamil SR with US shipping. You can order Verapamil SR online once your prescription is verified. Check the current Verapamil SR price and see how Canadian costs compare. If you need multiple fills, consider adding more than one month to lower per-packaging costs and reduce trips.

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Availability and Substitutions

Availability can vary by strength and release design. If a specific SR tablet or ER capsule is out of stock, your prescriber may recommend a therapeutically equivalent alternative or a different release formulation with an adjusted schedule. We will coordinate any changes only after your clinic confirms suitability.

Patient Suitability and Cost Saving Tips

Good candidates are adults with hypertension or angina who need a calcium channel blocker and can follow daily dosing. It may not be suitable in significant conduction disease, severe hypotension, or decompensated heart failure. People with liver impairment might need lower doses.

To save on cost, ask about generics, 90-day supplies, and synchronized refills. Set refill reminders so you never miss doses. Explore our cardiovascular category pages to compare options across classes, including Hypertension Cardiovascular and Heart Health Medications.

Questions to Ask Your Clinician

• Is an SR tablet or an ER capsule best for my condition?
• What starting dose fits my blood pressure and heart rate?
• How should we monitor for bradycardia or swelling?
• Do I need a statin dose change with verapamil?
• Is it safe to combine with my beta blocker or digoxin?
• Should I avoid grapefruit or certain supplements?
• How often will we reassess dosing and goals?

Authoritative Sources

• FDA DailyMed: Verapamil Extended-Release
• MedlinePlus: Verapamil
• Health Canada DPD: Drug Product Database

Ready to start? Order Verapamil SR online with US delivery from Canada.

Information here is educational and not a substitute for professional medical advice. Always follow your clinician’s directions and the official label.