Jentadueto® Tablets for Type 2 Diabetes

Jentadueto® is a prescription tablet that combines linagliptin and metformin for adults with type 2 diabetes. This page explains dosing basics, safety, strengths, and practical tips so you can order confidently. Your medicine ships from Canada to the US with Canadian pricing, helpful if you pay without insurance.

What Jentadueto® Is and How It Works

Jentadueto® contains two medicines that target high blood sugar in different ways. Linagliptin is a DPP-4 inhibitor that helps raise levels of incretin hormones. This supports insulin release after meals and reduces the liver’s glucose output when glucose is high. Metformin is a biguanide that lowers hepatic glucose production and improves insulin sensitivity in muscle and fat. Taken together and paired with diet and exercise, the combination helps improve overall glycemic control.

CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order. Your tablets are filled in Canada and delivered to US addresses.

Who Jentadueto® Is For

Jentadueto is indicated for adults with type 2 diabetes mellitus as an adjunct to diet and exercise. It may be used when metformin alone is not enough, or to replace separate tablets of linagliptin and metformin.

Jentadueto is not for type 1 diabetes or for the treatment of diabetic ketoacidosis. It should not be used in people with significant renal impairment or in those with known hypersensitivity to linagliptin, metformin, or any tablet component. Use caution in conditions that may increase the risk of lactic acidosis, such as severe infection, dehydration, or hepatic disease, and in those who drink alcohol excessively. For general background on the condition it treats, see our Type 2 Diabetes category.

Dosage and Usage

Jentadueto is usually taken twice daily with meals. Starting doses often mirror a patient’s current metformin regimen while adding linagliptin. If starting metformin is appropriate, a common initiation is 2.5 mg/500 mg twice daily with the morning and evening meal, then increase the metformin component gradually to improve tolerability. Do not exceed the maximum recommended daily dose as outlined in the official label.

Swallow tablets whole with water. Taking Jentadueto with food helps reduce gastrointestinal side effects associated with metformin. If you are already on metformin, your clinician may choose a strength that is closest to your current daily metformin dose. If you are also on insulin or a sulfonylurea, your clinician may consider lowering those agents to reduce hypoglycemia risk. For more details on dosing concepts, review Jentadueto Uses Dosage and the metformin-specific overview in Metformin Dosage.

Strengths and Forms

Jentadueto immediate-release tablets are commonly available in these strengths:

• Linagliptin 2.5 mg / metformin 500 mg
• Linagliptin 2.5 mg / metformin 850 mg
• Linagliptin 2.5 mg / metformin 1000 mg

Availability may vary by pharmacy and inventory. Your prescriber will choose the strength that aligns with your current therapy and treatment goals. If you are comparing options, note that a “linagliptin 2.5 mg / metformin 1000 mg tablets price” query refers to the highest metformin strength in this immediate-release line.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. If it is close to the next dose, skip the missed dose and resume your usual schedule. Do not double doses. Keeping doses with meals and using reminders can help you stay consistent.

Storage and Travel Basics

Store Jentadueto at room temperature, ideally 20–25°C (68–77°F). Protect the tablets from moisture and heat. Keep the bottle tightly closed and out of reach of children. When traveling, carry your medicine in your hand luggage, keep it in the original labeled container, and bring a copy of your prescription. Avoid leaving tablets in a hot car or in a bathroom with high humidity.

Benefits

The combination of linagliptin and metformin offers complementary glucose control. The tablet format simplifies therapy for people who would otherwise take separate linagliptin and metformin. Taking it with meals makes it straightforward to fit into a daily routine. Many people appreciate that linagliptin does not require dose adjustment based on kidney function, while the metformin component requires standard renal safety checks under clinical guidance.

Side Effects and Safety

• Gastrointestinal upset such as diarrhea, nausea, stomach pain, or gas
• Headache or dizziness
• Upper respiratory symptoms including cough or sore throat
• Rash or mild skin reactions
• Back pain or joint discomfort

Serious risks are uncommon but important. Metformin can rarely cause lactic acidosis, which is a medical emergency. DPP-4 inhibitors, including linagliptin, have been associated with pancreatitis and severe joint pain. Hypersensitivity reactions can occur. The risk of hypoglycemia rises when Jentadueto is used with insulin or a sulfonylurea. Long-term metformin use may reduce vitamin B12 levels; your clinician may check levels if you have anemia or neuropathy symptoms. For a deeper look at common and serious reactions, read Jentadueto Side Effects.

Drug Interactions and Cautions

Tell your clinician and pharmacist about all prescription drugs, OTC products, and supplements you take. Key interaction considerations include:

• Alcohol, which can raise the risk of lactic acidosis with metformin
• Carbonic anhydrase inhibitors such as topiramate or acetazolamide, which may increase acidosis risk
• Iodinated contrast agents for imaging; metformin is typically paused around the time of contrast based on renal status
• Strong inducers such as rifampin, which can reduce linagliptin exposure
• Cationic drugs eliminated renally (for example, cimetidine) may compete with metformin for renal tubular secretion

Discuss sick-day rules, planned surgeries, and imaging procedures with your clinic. If you use insulin or a sulfonylurea, review signs of low blood sugar and how to treat it. See our overview on Metformin Hypoglycemia for more context.

What to Expect Over Time

Your clinician will often adjust the metformin component gradually to improve tolerability. Gastrointestinal symptoms usually lessen after the first weeks. Blood glucose measures may change within days to weeks, while A1C reflects the average over about three months. Your care team may track kidney function and vitamin B12 during longer-term use. Ongoing lifestyle measures, including meal planning and activity, remain important.

Compare With Alternatives

Another DPP-4 inhibitor plus metformin option is sitagliptin with metformin, including extended-release formats such as Janumet® XR Products. Some people with type 2 diabetes may also use insulin if oral medicines are not enough; a rapid-acting option for mealtime coverage is the Novorapid® Cartridge. Your clinician can help decide which therapy aligns with your targets, other conditions, and preferences. Alternatives outside the DPP-4 class include SGLT2 inhibitors, GLP-1 receptor agonists, or metformin alone.

Pricing and Access

CanadianInsulin lists transparent Jentadueto price information with Canadian pricing and US delivery from Canada. You can review Jentadueto cost details by strength and quantity, including the Jentadueto 2.5/1000 mg price and options for Jentadueto 2.5/500 mg tablets. Many customers compare Jentadueto tablet price options when looking at a cash price. If you need Jentadueto price from Canada and Jentadueto US shipping, you can view options and proceed through secure checkout. We also display Jentadueto cost without insurance so you can plan out-of-pocket spending. If you prefer, you can Order Jentadueto 2.5/1000 mg after comparing doses. People sometimes search for linagliptin/metformin 2.5 mg/1000 mg price to match their prescription label wording. For seasonal offers, visit our Promotions page. Encrypted checkout helps protect your information.

Availability and Substitutions

Supply can vary by strength or package size. If a particular tablet strength is not available, your prescriber may recommend a comparable alternative dose or a different approved medicine from the same class. Pharmacy teams dispense according to your prescription and the product on file. Ask your clinic before making any substitution.

Patient Suitability and Cost Saving Tips

Jentadueto may be a good option for adults who would benefit from combining a DPP-4 inhibitor with metformin in a single tablet. It is not for type 1 diabetes or acute ketoacidosis. People with significant renal or hepatic impairment, metabolic acidosis, or a history of serious hypersensitivity to components should avoid it. Those with pancreatitis history or risk factors should discuss the benefits and risks with their clinician.

To save on overall costs, consider:

• Requesting a multi-month supply if suitable for your care plan
• Using refill reminders so you do not miss doses or rush orders
• Reviewing tablet strengths with your clinician to match the most efficient quantity
• Consolidating prescriptions when possible to streamline shipping

Questions to Ask Your Clinician

• Which Jentadueto strength best matches my current metformin dose?
• How should I adjust other diabetes medicines to lower hypoglycemia risk?
• What signs of lactic acidosis or pancreatitis should I watch for?
• Do I need vitamin B12 checks during long-term therapy?
• Should I pause metformin for contrast imaging or surgery?
• What A1C target am I aiming for, and when should I recheck labs?
• If I develop stomach upset, how should I manage timing with meals?

Authoritative Sources

• FDA DailyMed
• Health Canada DPD
• Boehringer Ingelheim

Ready to proceed? Place your Jentadueto request with prompt, express shipping from Canada to the US.