Repaglinide Tablets for Type 2 Diabetes

Repaglinide is an oral diabetes medicine used to reduce after-meal blood sugar in adults with type 2 diabetes. It belongs to the meglitinide class and helps the pancreas release insulin around mealtimes. This page explains how the treatment works, who it may suit, and how to use it safely with US delivery from Canada, including options if you shop without insurance.

What Repaglinide Is and How It Works

Repaglinide is a short-acting insulin secretagogue in the meglitinide class. It binds to beta-cell receptors in the pancreas, leading to rapid insulin release with meals. This timing targets postprandial spikes and complements diet and exercise plans.

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

Typical repaglinide uses include adjunct treatment to diet and exercise to improve glycemic control in adults with type 2 diabetes. It may be used alone or with metformin when additional post-meal control is needed. For a deeper overview of the class, see our plain-language primer on Meglitinides Drugs.

Who It’s For

This medicine is indicated for adults with type 2 diabetes when post-meal glucose rises remain above targets despite diet and activity. It can be used as monotherapy or combined with other non-insulin agents under clinician guidance. The prandin generic name is repaglinide.

It is not for type 1 diabetes or for the treatment of diabetic ketoacidosis. People with significant liver impairment, recurrent hypoglycemia, or those on interacting medicines may need an alternative. Discuss pregnancy and breastfeeding plans with your clinician before use.

If you are learning about the condition itself, our overview of Type 2 Diabetes offers additional context about diagnosis and care goals.

Dosage and Usage

Take this treatment before meals as directed by your prescriber. Doses are typically taken within 30 minutes prior to eating. If you skip a meal, you usually skip the dose for that meal. Follow the official label and your care team’s instructions for any changes.

When referenced for labeling examples, repaglinide 1mg is a commonly used strength for initiation or titration. Clinicians consider prior therapy, glycemic targets, and meal patterns when selecting a regimen. Combining with metformin is common when fasting and post-meal glucose both need control.

Swallow tablets whole with water. Coordinate dosing with consistent meal timing when possible. For a practical review of titration concepts, see our educational article Side Effects Dosage. For broader therapy context, browse our Diabetes Medications category.

Strengths and Forms

Repaglinide tablets are available in film‑coated oral tablets. Market availability can vary by manufacturer and by pharmacy stock.

• repaglinide 0.5 mg
• 1 mg tablet
• 2 mg tablet

Strength options may vary by supplier. Tablet color and imprint can differ by manufacturer.

Missed Dose and Timing

If you forget to take a dose and you are still about to eat, take it before the meal. If the meal was skipped or already finished, usually wait until the next scheduled mealtime dose. Do not double up to “catch up.” Keep a small routine reminder, such as setting alarms linked to meals, to help with adherence.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. Do not use tablets that are chipped, discolored, or past the labeled expiration date.

When traveling, keep your medication in its original labeled container. Pack it in a carry-on bag to avoid temperature extremes. Bring a medication list and a copy of your prescription, especially when crossing borders or changing time zones. If you use multiple diabetes therapies, plan meal timing and monitoring supplies accordingly. For related items and guidance, our Diabetes category may be helpful.

Benefits

This medicine can help reduce post-meal blood sugar due to its rapid onset of action around mealtimes. Dosing flexibility allows alignment with variable meal schedules. When combined with metformin, it can address both fasting and prandial glucose patterns.

The repaglinide drug class offers short-duration action, which may reduce exposure when meals are skipped. However, meal-related dosing requires attention to timing, and clinical monitoring remains essential.

Side Effects and Safety

Common effects can include:

• Low blood sugar symptoms such as shakiness or sweating
• Headache or dizziness
• Upper respiratory symptoms
• Gastrointestinal upset
• Joint or back discomfort

Serious risks include clinically significant hypoglycemia, especially if meals are delayed, calories are reduced, or combined therapies increase insulin levels. Liver enzyme elevations have been reported. Allergic reactions are rare but can occur. Contact a clinician if you experience persistent or severe symptoms, or signs of low blood sugar that do not improve with fast-acting carbohydrates.

If you use insulin or sulfonylureas, discuss hypoglycemia risk and monitoring. For a deeper dive on risks and practical tips, see our article on Prandin Side Effects.

Drug Interactions and Cautions

Gemfibrozil is contraindicated due to a marked increase in repaglinide exposure. Strong CYP2C8 inhibitors can raise levels. Clopidogrel may increase levels; clinicians often avoid the combination or adjust therapy. Rifampin can lower exposure, potentially reducing effect. Other agents affecting blood sugar, such as beta-blockers, can mask adrenergic symptoms of hypoglycemia.

Alcohol can potentiate or blunt glucose-lowering effects. Illness, stress, changes in diet, and changes in activity can alter insulin needs. People with moderate to severe hepatic impairment may require additional caution or alternative therapy. Always review your full medication and supplement list with your prescriber.

What to Expect Over Time

With consistent mealtime use and dietary planning, many patients observe improved postprandial readings. Effects begin around meals and wear off between meals. Your clinician may review glucose logs to guide adjustments. If combined therapy is used, the goal is balanced fasting and post-meal control without undue hypoglycemia.

Build habits to link dosing with meals and to carry a quick source of glucose. Keep scheduled check-ins for lab work and monitoring. Reliable routines can help maintain consistent results.

Compare With Alternatives

Alternatives from other classes may suit different needs. For example, an SGLT2 inhibitor like Dapagliflozin works by promoting urinary glucose excretion and may help with cardiovascular or renal goals per label. A GLP‑1 receptor agonist such as Trulicity Pens is injected weekly and can support post-meal and fasting control, with gastrointestinal effects common in early therapy.

Class choice depends on individual goals, comorbidities, and safety considerations. Discuss options with your clinician to select a regimen that fits your overall plan.

Pricing and Access

Canadian pharmacy pricing can offer value for many patients. You can review the repaglinide price on our product page and compare available strengths. We provide clear checkout steps and support documents for your records. We also offer US shipping from Canada with tracking.

Looking for periodic savings? See current site-wide offers on our Promotions page. Checkout uses encrypted processing for your protection.

Availability and Substitutions

Availability can vary due to manufacturer supply and pharmacy inventory. If this product is temporarily unavailable, your prescriber may recommend another oral agent from the same or a different class. We will fulfill the prescription to the approved product and strength when stock permits.

Patient Suitability and Cost-Saving Tips

This treatment may suit adults whose primary challenge is high post-meal glucose, particularly when fasting levels are closer to target. It may not suit those with frequent hypoglycemia or significant hepatic impairment. A repaglinide prescription is required for dispensing.

To reduce costs, consider multi-month quantities if appropriate and permitted by your prescriber. Set refill reminders to avoid gaps in therapy. Compare combination regimens to minimize duplicate copays when possible. If you pay without insurance, check whether a longer supply aligns with clinician guidance and storage limits.

For broader therapy context, review our Non-Insulin options and explore related Diabetes Medications categories to understand how classes differ.

Questions to Ask Your Clinician

• Meal timing fit: How should I coordinate doses with my meals?
• Combination therapy: Should I use this with metformin or another class?
• Hypoglycemia plan: What are my steps if I feel low?
• Monitoring: How often should I check glucose with this regimen?
• Interactions: Do any of my medicines affect this treatment?
• Liver health: Do I need baseline or follow-up liver tests?
• Travel: How should I handle time zone changes and meal shifts?

Authoritative Sources

For complete prescribing information and safety details, review official sources:

• FDA label for PRANDIN (repaglinide) on the FDA website: FDA Prescribing Information (PDF)
• DailyMed listing for repaglinide with full labeling: DailyMed Repaglinide Label
• Health Canada Drug Product Database search page: Health Canada DPD

Ready to proceed? You can add the item to cart and complete checkout with prompt, express, cold-chain shipping and temperature-controlled handling when required.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.