Please note: a valid prescription is required for all prescription medication.
This biological medicine helps manage plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. Here you will find dosing basics, strengths, safety, and how ordering works with US delivery from Canada. You can compare options, check typical costs without insurance, and see storage and travel tips.
What Stelara® Is and How It Works
Stelara is the brand name for ustekinumab, a monoclonal antibody. It targets interleukin-12 and interleukin-23, cytokines that drive chronic inflammation in skin and gut. By blocking these pathways, the treatment can reduce plaques, joint symptoms, and intestinal inflammation over time.
CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.
This medicine is given by subcutaneous injection using a prefilled syringe. Some conditions start with an intravenous infusion, then move to maintenance injections. Your clinician selects the schedule based on the condition and clinical history.
Who It’s For
Ustekinumab is approved for adults with moderate to severe plaque psoriasis and active psoriatic arthritis. It is also used for adults with moderately to severely active Crohn’s disease or ulcerative colitis. Some pediatric uses are listed on the official label. People with active, serious infections should not start this therapy. Tell your prescriber about tuberculosis exposure, recent vaccines, or a history of malignancy before initiation.
Explore related conditions and options in Plaque Psoriasis, Ulcerative Colitis, and Psoriatic Arthritis.
Dosage and Usage
The label includes weight-based dosing for skin disease, with injections at week 0 and week 4, then maintenance at regular intervals. For Crohn’s disease and ulcerative colitis, treatment often begins with a one-time intravenous infusion, followed by subcutaneous injections at a steady interval. Your prescriber will determine the exact schedule.
Allow the syringe to reach room temperature before use. Inspect the solution; do not use if discolored, cloudy, or containing particles. Inject into the thigh, abdomen, or upper arm. Rotate sites and avoid areas that are tender, bruised, or scarred.
See more options for joint and skin management in Psoriatic Arthritis.
Strengths and Forms
The prefilled syringe is typically available in two strengths used for maintenance dosing. Your prescriber decides which presentation fits your condition and weight. Availability may vary by pharmacy and jurisdiction.
Patients sometimes compare the Ustekinumab 45 mg/0.5 mL syringe cost with the higher-strength syringe. Actual selection should follow the official label and prescriber direction.
Missed Dose and Timing
If you miss an injection, take it as soon as you remember unless it is close to the next scheduled dose. Do not double up. Contact your healthcare professional to confirm the timing for the following dose. Keep to a consistent interval once the schedule is re-established.
Storage and Travel Basics
Store the prefilled syringe in the refrigerator. Keep it in the original carton to protect from light. Do not freeze or shake. When traveling, place the syringe in an insulated bag with a cold source that does not allow freezing. Keep it out of the reach of children and pets. For convenience, bring a copy of your prescription and a travel letter if you are flying. This product uses temperature-controlled handling when required.
For needle know-how, see BD Needles.
Pen Handling and Sharps Disposal
Wash hands before handling the syringe. Clean the skin with an alcohol swab and let it dry. Pinch the skin gently and insert the needle at the angle instructed in the patient guide. Depress the plunger steadily until the syringe is empty. Do not recap the needle. Place the used syringe into an FDA-cleared sharps container. When full, follow local guidance for disposal. Never throw loose needles or syringes into household trash.
Benefits
This therapy offers infrequent maintenance dosing for many indications. It can reduce skin plaques, ease joint discomfort and swelling, and support remission goals in inflammatory bowel disease. Many patients value at-home administration with a prefilled syringe and a predictable maintenance interval. Your results can vary by condition, prior treatments, and overall health.
Side Effects and Safety
- Headache or fatigue
- Upper respiratory symptoms
- Injection site redness or tenderness
- Diarrhea or stomach discomfort
- Itching or mild rash
Serious risks include severe infections, reactivation of latent tuberculosis, allergic reactions, and rare neurological events. This treatment may increase the risk of some malignancies. Tell your prescriber immediately if you develop fever, shortness of breath, persistent cough, hives, dizziness, or swelling of the face or throat. Review the full Prescribing Information for complete warnings.
Drug Interactions and Cautions
Avoid live vaccines during therapy. Non-live vaccines may be given, but immunogenicity can vary. Using multiple immunosuppressants can raise infection risk; your prescriber will consider the overall regimen. Screen for tuberculosis before starting. Report any signs of infection promptly. For mechanism comparisons, see Ustekinumab Vs Adalimumab.
What to Expect Over Time
Most people follow an induction plan and then move to a steady maintenance rhythm. Skin or gut symptoms may improve gradually as inflammation decreases. Keep track of your symptom patterns, photos of plaques, or bowel habit changes to share at follow-up visits. Budgeting for treatment matters; the Stelara Prefilled Syringe cost per syringe can guide refill planning. If your condition flares, contact your prescriber to review adherence and rule out infection.
Learn more about immune conditions in Diabetes And Autoimmune Disorders.
Compare With Alternatives
Other biologics may be appropriate based on diagnosis and history. Tumor necrosis factor inhibitors and IL-17 or IL-23 pathway inhibitors use different mechanisms. Two commonly prescribed alternatives include Humira and Skyrizi Pre Fill. Your clinician will consider prior response, comorbidities, and monitoring needs when discussing options.
Pricing and Access
Canadian pricing can offer meaningful cash-pay value for eligible patients. You can review fee ranges and compare refill intervals before you place an order. Our team supports prescription verification, secure checkout, and discreet packaging. Stelara Prefilled Syringe price details are shown on this page.
We provide transparent information for self-pay users. This includes a clear explanation of the Stelara Prefilled Syringe price without insurance and guidance on what affects changes between fills. Payment options vary by pharmacy partner. Ships from Canada to US for qualifying orders.
Looking for seasonal offers? See Promotions when available.
Availability and Substitutions
Supply can vary by strength and pack size. If a specific presentation is unavailable, your prescriber may recommend an alternative that fits your diagnosis and dosing plan. Ask your clinician before any switch. You can Order Stelara Prefilled Syringe online once your prescription is verified.
Patient Suitability and Cost-Saving Tips
This treatment may suit adults with moderate to severe plaque psoriasis, active psoriatic arthritis, or inflammatory bowel disease who need biologic therapy. It may not be appropriate if you have a severe, active infection or cannot complete recommended screenings. TB testing and vaccine review are standard before initiation.
To lower expenses, consider longer refill intervals when clinically appropriate, coordinate lab visits with injection dates, and set reminders for renewals. Ask your prescriber whether syringes can be dispensed in multi-month quantities. Discuss weight-based dosing and how that impacts the Ustekinumab Prefilled Syringe 90 mg price. Keep receipts and documentation if you track out-of-pocket spending for tax or reimbursement.
Questions to Ask Your Clinician
- Induction plan and maintenance interval
- Screening tests needed before starting
- Signs of infection to report right away
- Vaccine timing and restrictions
- How to rotate injection sites
- When to schedule follow-up assessments
Authoritative Sources
| Source | Link |
|---|---|
| FDA Prescribing Information | DailyMed |
| Health Canada Drug Product Database | Health Canada DPD |
| Manufacturer Information | Janssen Label |
Ready to proceed? Start your order for US shipping from Canada with prompt, express, cold-chain shipping. This page is informational and is not a substitute for medical advice; always follow your prescriber’s instructions.
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How does ustekinumab work in immune-mediated disease?
Ustekinumab is a monoclonal antibody that binds interleukin‑12 and interleukin‑23. These cytokines help regulate immune responses that drive chronic inflammation in plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. By blocking these pathways, the therapy can reduce inflammatory signals in skin and gut. It is not an immediate reliever and should be used as directed on the label. Your prescriber will monitor for infections and other safety considerations during treatment.
Can I switch to ustekinumab from another biologic?
Switching may be considered when efficacy, tolerability, or convenience are concerns. Your healthcare professional will review prior biologics, disease activity, and infection risk before planning a transition. Washout timing and overlap depend on the prior agent’s mechanism and half-life. Vaccination status and tuberculosis testing are often reassessed. Do not change therapy without discussing benefits and risks with your prescriber and reviewing the official label.
What tests are needed before starting treatment?
Baseline screening commonly includes tuberculosis testing and a review of recent vaccinations. Some clinicians order hepatitis screening, complete blood count, and liver function tests based on history and comorbidities. The aim is to identify infection risks before immunomodulatory therapy. Ongoing monitoring is individualized. Follow your prescriber’s testing plan and report any new symptoms such as fever, cough, or shortness of breath during therapy.
Can I receive vaccines while using this medicine?
Live vaccines should generally be avoided during therapy. Inactivated vaccines may be administered, but response can vary. Your clinician will plan vaccine timing relative to doses. Family and close contacts should also follow vaccine guidance to reduce exposure risks. Bring your immunization record to visits so your prescriber can update plans safely. Always consult the label and your healthcare professional for specific vaccine recommendations.
How should I inject the prefilled syringe?
Wash your hands, then clean the injection site with an alcohol swab and let it dry. Inject into the thigh, abdomen, or upper arm as instructed. Allow the syringe to reach room temperature before use. Do not inject into red, tender, or scarred skin. After injecting, place the used syringe in a sharps container. Never recap or reuse. Call your prescriber if you see unusual redness, swelling, or persistent pain at the site.
How do I travel with refrigerated biologics?
Keep the syringe in its carton until use. Transport it in an insulated case with a cold source that will not freeze the medicine. Avoid direct sunlight and temperature extremes. Bring your prescription and travel letter, especially when flying. At your destination, store the syringe in a refrigerator. If local refrigeration is uncertain, discuss contingency plans with your prescriber before departure.
What should I do if I develop an infection during therapy?
Report signs of infection such as fever, chills, persistent cough, or shortness of breath to your clinician promptly. Your prescriber will assess severity and decide if doses should be delayed. Avoid starting new immunosuppressants unless your care team agrees. Keep up with recommended monitoring and infection prevention steps. Do not stop or restart therapy without professional guidance and reference to the product’s prescribing information.
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