Aldactazide® Tablets for Hypertension and Edema

Aldactazide® combines spironolactone and hydrochlorothiazide to treat hypertension and edema. It pairs a potassium-sparing diuretic with a thiazide to support fluid control. You can access this product with US delivery from Canada, and this page explains access options, including paying without insurance.

What Aldactazide Is and How It Works

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Spironolactone antagonizes aldosterone in the distal nephron to reduce sodium and water reabsorption while conserving potassium. Hydrochlorothiazide inhibits sodium-chloride transport in the distal tubule, increasing urine output. Together, the combination supports fluid balance and helps lower blood pressure. Formulations such as Spironolactone/Hydrochlorothiazide 25/25 mg tablets may be selected based on clinical need and tolerability. Always follow the approved label and your prescriber’s directions.

Who It’s For

This treatment is used for adults with essential Hypertension when a fixed-dose diuretic combination is appropriate. It is also indicated for edema related to congestive heart failure, hepatic cirrhosis, or nephrotic syndrome when an aldosterone antagonist is desired. People with hyperkalemia, Addison’s disease, anuria, or severe renal impairment should not use this medicine. Those with a history of sulfonamide allergy may react to hydrochlorothiazide. Suitability requires review of kidney function, electrolytes, and concurrent therapies.

Dosage and Usage

Dosing is individualized by the prescriber. The tablet is usually taken once daily in the morning; some patients may require a different schedule. Take with food if stomach upset occurs, and swallow tablets whole with water. Maintain consistent timing each day. Do not change your regimen without medical guidance. Avoid high-potassium salt substitutes unless instructed otherwise. Follow the monitoring plan for electrolytes and kidney function provided by your prescriber.

Strengths and Forms

Fixed-dose oral tablets are commonly supplied in the following strengths:

• 25/25 mg tablets
• 50/50 mg tablets

Availability can vary by manufacturer and by pack size. The pharmacy will dispense a product that matches your valid prescription.

Missed Dose and Timing

If a dose is missed, take it the same day when remembered. Skip the missed dose if it is close to the next scheduled time. Do not double doses. Because it increases urination, a morning dose is typically preferred to limit nighttime bathroom trips. Consistent daily use supports long-term blood pressure goals.

Storage and Travel Basics

Store tablets at room temperature in a dry place, protected from heat and light. Keep medicine in the original, child-resistant container. Do not store in a bathroom. For travel, carry your prescription-labeled bottle in hand luggage and bring a copy of the prescription. Use a simple pill organizer for short trips, and keep the labeled container for reference. Keep out of reach of children and pets.

Benefits

This combination provides complementary diuretic actions in a single tablet. It can help lower blood pressure while reducing the risk of potassium loss seen with some diuretics. Using one product may simplify regimens compared with separate agents. Regular use may lessen ankle swelling, abdominal fluid, or other edema-related symptoms when part of an overall care plan. Many patients find a morning routine practical.

Side Effects and Safety

• Increased urination
• Dizziness or lightheadedness
• Nausea or abdominal discomfort
• Headache or fatigue
• Muscle cramps
• Breast tenderness or gynecomastia
• Menstrual irregularities
• Rash or photosensitivity

Serious effects can include hyperkalemia, severe hyponatremia, marked hypotension, dehydration, kidney dysfunction, or hypersensitivity reactions. Seek urgent care for fainting, severe weakness, irregular heartbeat, or swelling of the face or throat. Diuretics can affect glucose control and interact with diabetes medicines; monitoring may be needed. Many patients undergo periodic checks of potassium and creatinine as part of safe use.

Drug Interactions and Cautions

Concomitant use with potassium supplements, potassium-sparing agents, ACE inhibitors, ARBs, or trimethoprim can increase potassium. NSAIDs may blunt diuretic response and affect renal function. Thiazides can raise lithium levels; close monitoring is required if used together. Electrolyte shifts may influence digoxin response. Alcohol and other antihypertensives can add to blood pressure lowering. Avoid potassium-containing salt substitutes unless directed. Patients with gout, lupus, kidney disease, or liver disease require careful evaluation. These cautions are common in Cardiovascular Disease management.

What to Expect Over Time

Urination often increases after starting and then stabilizes with regular use. Blood pressure may improve when the medicine is taken consistently and paired with lifestyle measures. Some patients need laboratory monitoring and regimen adjustments, based on clinical assessment. Keeping a simple log of home readings, if recommended, can help guide visits. For additional context on hypertension care, see Atenolol And Hypertension.

Compare With Alternatives

Alternatives include single-agent thiazides or other combination therapies. For patients needing a thiazide alone, Hydrochlorothiazide is a well-established option. When an ACE inhibitor plus thiazide is appropriate, Ramipril Hctz may be considered. Selection depends on blood pressure targets, comorbidities, laboratory values, and prior response as assessed by the prescriber.

Pricing and Access

You can review Spironolactone HCTZ price information and compare generic sources on our product pages. We also outline Aldactazide cash price considerations for self-pay buyers. Orders are processed with US delivery from Canada, and current availability is shown before checkout. For occasional savings, visit our Promotions page. Checkout is encrypted, and prescriptions are verified. For broader context on heart and blood pressure care, read Managing Diabetes And Hypertension.

Availability and Substitutions

Stock can vary by manufacturer and tablet count. If a specific presentation is unavailable, a prescriber may recommend an appropriate therapeutic alternative. We provide Spironolactone HCTZ Canadian pricing references so you can compare options when discussing choices with a clinician. Final dispensing depends on a valid prescription and pharmacy supply.

Patient Suitability and Cost-Saving Tips

Candidates often include adults with hypertension or edema who benefit from a potassium-sparing component. Not all patients are appropriate, particularly those with marked hyperkalemia or severe renal dysfunction. For budgeting, Spironolactone HCTZ self-pay planning may benefit from multi-month fills when allowed. Ask the prescriber about quantity limits and timing for refills. Choosing generics, coordinating lab work with routine visits, and avoiding missed doses can help manage overall costs.

Questions to Ask Your Clinician

• Potassium checks: how often and where to draw labs.
• Salt substitutes: whether to avoid potassium-containing products.
• Dosing time: morning schedule and plans for adjustments.
• Interactions: using NSAIDs, lithium, or supplements safely.
• Edema tracking: daily weights and warning signs to report.
• Coverage: expected Spironolactone HCTZ out of pocket costs under the plan.

Authoritative Sources

FDA DailyMed LabelHealth Canada DPD

Order at CanadianInsulin for prompt US shipping from Canada with temperature-controlled handling when required. Educational content only; follow the approved label and prescriber guidance.