Please note: a valid prescription is required for all prescription medication.
Valsartan HCT is a fixed-dose combination of valsartan and hydrochlorothiazide used to treat high blood pressure. You can order it from Canada with US delivery from Canada, and it ships to the US with Canadian pricing. This page explains how it works, who it suits, dosing basics, safety, and how to buy online, including if you pay without insurance.
What Valsartan HCT Is and How It Works
At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic. The combination is known by the brand name Diovan HCT®. It pairs valsartan, an angiotensin II receptor blocker (ARB), with hydrochlorothiazide, a thiazide diuretic. Valsartan relaxes blood vessels by blocking the effects of angiotensin II at the AT1 receptor. Hydrochlorothiazide helps your kidneys remove extra salt and water. Together they lower blood pressure more than either component alone in appropriate patients.
Valsartan HCT is taken by mouth, usually once daily. It can be used when blood pressure is not adequately controlled on a single agent, or as a replacement for the two medicines given separately. Your clinician chooses the tablet strength that matches your current therapy and goals.
Who Valsartan HCT Is For
This medicine is for adults with hypertension who may benefit from a single tablet that combines an ARB and a diuretic. It may be considered if you are not at goal on valsartan alone or another first-line agent. Some patients started directly on combination therapy reach targets more efficiently, under medical supervision.
Avoid use if you are pregnant or planning pregnancy. ARBs can harm an unborn baby. Do not use if you cannot make urine (anuria) or if you have a known allergy to sulfonamide-derived medicines. Use caution with severe kidney or liver disease and in primary aldosteronism. People with gout, very low sodium or potassium, or significant dehydration need careful evaluation.
If your clinician prefers to keep you on a single ARB, you can review Valsartan. For condition education, see our category on High Blood Pressure and read about kidney risks in Diabetic Nephropathy.
Dosage and Usage
Common regimens follow the approved label. Valsartan HCT is taken once daily, with or without food, at the same time each day. Clinicians often start with a lower combination tablet and adjust as needed over several weeks. If you are already taking valsartan and hydrochlorothiazide separately, your prescriber may switch you to the closest equivalent strength.
Typical starting options include 80/12.5 mg or 160/12.5 mg once daily. If additional control is needed, higher strengths such as 160/25 mg, 320/12.5 mg, or 320/25 mg may be used. The maximum approved dose is 320/25 mg once daily. People who are volume-depleted from diuretics or have low sodium may need a careful, lower starting dose and monitoring.
Take each dose with water. Many patients prefer a morning schedule to match the diuretic effect. Consistent use is important; do not stop suddenly unless your clinician advises.
Strengths and Forms
Valsartan HCT is supplied as film-coated tablets in multiple strengths. Availability may vary by manufacturer and pharmacy.
- Valsartan HCT 80/12.5 mg tablets
 - Valsartan HCT 160/12.5 mg tablets
 - Valsartan HCT 160/25 mg tablets
 - Valsartan HCT 320/12.5 mg tablets
 - Valsartan HCT 320/25 mg tablets
 
Missed Dose and Timing
If you miss a dose, take it when you remember on the same day. If it is close to your next dose, skip the missed dose and take the next one at the regular time. Do not take two doses at once. Try to take the medicine at the same time each day to build a steady routine.
Storage and Travel Basics
Store tablets at room temperature in a dry place, generally 20 to 25°C (68 to 77°F). Keep the bottle tightly closed and away from moisture and heat. When traveling, carry your labeled prescription in your hand luggage and keep it in the original container. Our checkout is encrypted to help protect your information.
Benefits
Lowering high blood pressure reduces the risk of stroke, heart attack, and kidney problems. Valsartan HCT combines two well-studied mechanisms in one daily tablet, which can simplify your regimen. The ARB component targets blood vessel constriction, while the diuretic helps remove excess fluid and sodium.
Side Effects and Safety
- Dizziness or lightheadedness, especially when standing up
 - Headache or fatigue
 - Increased urination
 - Nausea, stomach upset, or diarrhea
 - Muscle cramps
 - Skin sensitivity to sun or rash
 - Changes in potassium, sodium, or uric acid
 
Serious effects are less common but require medical attention. These can include severe low blood pressure, kidney problems, very low sodium or potassium, abnormal heart rhythm, severe allergic reactions or angioedema, sudden eye pain or vision changes (rare angle-closure glaucoma), and worsening gout. Do not use during pregnancy. If pregnancy is detected, stop the ARB component as directed by your clinician. People with diabetes should note that hydrochlorothiazide may affect glucose control; monitoring may be needed.
Drug Interactions and Cautions
- Do not combine with aliskiren if you have diabetes. Avoid combining with aliskiren in kidney impairment.
 - Use caution with ACE inhibitors and other ARBs. Your clinician may choose either class, not both. For background on ACE inhibitors, see Benazepril Uses.
 - Potassium-sparing diuretics, potassium supplements, or salt substitutes can raise potassium.
 - NSAIDs may reduce the blood pressure effect and affect kidney function in some patients.
 - Lithium levels can rise; toxicity is possible. Monitoring is advised if used together.
 - Cholestyramine and colestipol can reduce hydrochlorothiazide absorption; separate dosing times.
 - Alcohol and other blood pressure medicines can increase dizziness.
 
Tell your clinician about all medicines and supplements. If a different ARB/diuretic is recommended for you, another option is Telmisartan Hct.
What to Expect Over Time
Many people see blood pressure improvements within the first few weeks, with full effect after steady use. You may not feel different day to day. Keep taking your tablets as prescribed and attend follow-up visits for checks on blood pressure, electrolytes, and kidney function.
Compare With Alternatives
Some patients use the brand version, Diovan HCT®, when their prescriber requests it. Another ARB/diuretic pair is losartan plus hydrochlorothiazide, offered as Hyzaar DS®. Your clinician will choose based on your history, target blood pressure, and tolerance. Other ARB combinations like telmisartan/hydrochlorothiazide or candesartan/hydrochlorothiazide can also be appropriate in some cases.
Pricing and Access
Canadian pricing can help lower your overall Valsartan HCT cost. You can compare Diovan HCT price with combination options we carry. Many patients buy Valsartan Hydrochlorothiazide online to manage budget and therapy in one place. If you pay out of pocket, you can view the Valsartan HCT cash price across available strengths. You can also compare Diovan HCT 160/25 mg price with Diovan HCT 80/12.5 mg price and Diovan HCT 320/25 mg price to understand the range.
Order Diovan HCT from Canada or choose Valsartan HCT 160/12.5 mg order online when that is what your prescriber recommends. You will see options that reflect Diovan HCT Canadian pricing with US shipping. For savings updates and any Diovan HCT coupon policies we honor, visit Promotions. We provide prompt, express shipping from Canada to the US.
Availability and Substitutions
Availability can vary by strength and manufacturer. If a specific tablet is not in stock, your prescriber may recommend a therapeutically appropriate alternative strength or a different ARB/diuretic combination. Always follow your clinician’s guidance on substitutions.
Patient Suitability and Cost Saving Tips
Good candidates are adults with hypertension who need combination therapy and do not have contraindications such as pregnancy or anuria. People with kidney, liver, or electrolyte problems may still qualify but often need closer monitoring. If you have a history of severe allergy or angioedema, discuss the risks with your clinician first.
To save on overall cost, consider a multi-month supply if appropriate for your prescription. Align refills with routine lab checks. Set refill reminders so you do not run out. If you are switching from separate tablets, ask your clinician whether a single combination tablet could reduce your monthly cost and simplify your routine.
Questions to Ask Your Clinician
- Which starting strength is most appropriate for me?
 - How will we monitor my electrolytes and kidney function?
 - Should I take my dose in the morning or evening?
 - What side effects should prompt a call or visit?
 - How should we adjust my other blood pressure medicines?
 - Is a single combination tablet better than separate pills for me?
 - What should I know about use in hot weather or illness?
 
Authoritative Sources
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What is Valsartan HCT?
It is a fixed-dose tablet that combines valsartan (an ARB) and hydrochlorothiazide (a thiazide diuretic) to help lower high blood pressure in adults.
How do I take Valsartan HCT?
Take one tablet by mouth once daily, with or without food, at the same time each day. Your clinician will choose the strength and adjust as needed.
Which strengths are available?
Common strengths are 80/12.5 mg, 160/12.5 mg, 160/25 mg, 320/12.5 mg, and 320/25 mg tablets. Availability may vary by manufacturer.
Can I use it with other blood pressure medicines?
Often yes, but combinations are individualized. Do not combine with aliskiren if you have diabetes. Your clinician will coordinate other therapies.
What if I am pregnant or planning pregnancy?
Do not use ARBs during pregnancy. If pregnancy is detected, contact your clinician promptly to discuss stopping and alternative treatments.
Do I need lab monitoring?
Monitoring typically includes blood pressure, kidney function, and electrolytes. The diuretic can change sodium, potassium, and uric acid levels.
How is Valsartan HCT different from Diovan HCT?
Diovan HCT is the brand name for the valsartan/hydrochlorothiazide combination. Your clinician will specify which product they want you to receive.
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