Reglan® (Metoclopramida) para las náuseas y la gastroparesia

Reglan® (metoclopramide) is a dopamine antagonist that improves stomach emptying and treats nausea. This page explains how it works, who it may suit, and how to use it safely. CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order. Order metoclopramide from Canada with US delivery. You can also buy metoclopramide online without insurance if paying cash.

Qué es Reglan® y cómo funciona

Metoclopramide increases upper gastrointestinal motility and reduces nausea and vomiting. It blocks dopamine D2 receptors and has some 5-HT4 agonist and 5-HT3 antagonist activity. These actions speed gastric emptying and enhance coordination between the stomach and small bowel. Faster emptying can ease symptoms of diabetic gastroparesis. Central antiemetic activity helps control nausea from various causes.

We offer US shipping from Canada with Canadian pricing. This cross-border model can reduce out-of-pocket costs compared with many US cash prices.

Who Reglan® Is For

Metoclopramide is indicated for short-term treatment of symptomatic, documented diabetic gastroparesis. It may also be used for nausea and vomiting in select settings, as directed by a clinician. It can be considered in reflux-related symptoms when prokinetic therapy is appropriate.

People who should avoid metoclopramide include those with suspected or confirmed gastrointestinal obstruction, perforation, or bleeding. It is contraindicated in pheochromocytoma due to risk of hypertensive crisis. Avoid use in patients with a history of tardive dyskinesia or movement disorders. Use caution in Parkinson’s disease, depression, or seizure disorders. Dose adjustments may be needed in renal impairment and in CYP2D6 poor metabolizers.

For ulcer protection or reflux not requiring a prokinetic, options such as sucralfato puede ser considerado por su prescriptor.

Posología y utilización

Follow your prescriber and the official label. Typical adult dosing patterns include:

• Diabetic gastroparesis: Often 10 mg taken 30 minutes before each meal and at bedtime.
• Symptomatic GERD when prokinetic therapy is appropriate: Commonly 10 to 15 mg up to four times daily before meals and at bedtime.
• Maximum recommended dose is generally 40 mg per day in adults for oral use.
• Limit duration to the shortest time needed. Many patients use 2 to 8 weeks, and therapy longer than 12 weeks is not recommended due to tardive dyskinesia risk.

Pediatric dosing varies and requires specialist guidance. For injection, dosing and route (IV or IM) are determined clinically in a supervised setting.

Fortalezas y formas

Las presentaciones más habituales son:

• Tablets: 5 mg and 10 mg.
• Oral solution: 5 mg/5 mL.
• Injection: 5 mg/mL in vials or ampoules for IV or IM administration.

Availability may vary by pharmacy and country. Specific brands or formats can change.

Dosis omitida y momento oportuno

If you miss an oral dose, take it when remembered unless it is close to the next dose. If it is near the next dose, skip the missed dose and resume your schedule. Do not take two doses at once. For scheduled pre-meal dosing, timing relative to meals matters; try to take it 30 minutes before eating.

Almacenamiento y viaje

Store tablets and oral solution at controlled room temperature per label, away from moisture and light. Keep out of reach of children. Do not freeze liquid forms. For travel, keep medicine in its original packaging. Use a travel case that stays dry and avoids heat. Carry a copy of your prescription for border screening. If your product is an injection supplied for clinical use, transport as instructed by your care team.

Beneficios

Label-aligned benefits include improved gastric emptying and reduced nausea and vomiting in diabetic gastroparesis. For some patients with reflux-related symptoms, prokinetic action can help when used appropriately. Convenient oral tablet and liquid options support flexible dosing. Generic metoclopramide may offer a lower cost than many brand-only therapies.

Efectos secundarios y seguridad

• Common: Drowsiness, fatigue, restlessness, headache, dizziness, diarrhea, nausea, insomnia.
• Other possible: Anxiety, irritability, depression, agitation, increased urination, breast tenderness, galactorrhea.

Serious risks include tardive dyskinesia, a potentially irreversible movement disorder that becomes more likely with longer duration or higher cumulative dose. Other rare but serious effects include neuroleptic malignant syndrome, severe depression or suicidality, Parkinsonian symptoms, hypertension or hypotension, and methemoglobinemia. Stop the drug and seek urgent care if you develop uncontrolled movements, high fever with rigidity, severe mood changes, or fainting.

Because metoclopramide affects gastric emptying, absorption of other oral medicines can change. In people using insulin or sulfonylureas, faster gastric emptying can alter carbohydrate absorption and may impact glycemic control; monitor for hypoglycemia and discuss adjustments with your clinician.

Interacciones medicamentosas y precauciones

• Antipsychotics and other dopamine antagonists: Increased risk of extrapyramidal symptoms.
• SSRIs, SNRIs, and other serotonergic agents: Risk of serotonin syndrome, especially with combinations.
• Anticholinergics and opioids: May counteract prokinetic effects or add sedation.
• Alcohol and CNS depressants: Additive drowsiness and psychomotor impairment.
• Digoxin: Metoclopramide may reduce absorption; monitoring may be needed.
• Cyclosporine: Possible increased absorption; monitor levels as directed.
• MAOIs and catecholamine-releasing agents: Blood pressure effects may be potentiated.

Use caution in renal impairment and older adults. Avoid in history of tardive dyskinesia. Discuss risks in pregnancy and lactation; use only if benefits outweigh risks. Do not drive or operate machinery until you know how the medicine affects you.

Qué esperar con el tiempo

Nausea may ease soon after starting therapy, sometimes within the first doses. Gastroparesis symptoms such as early satiety, bloating, and vomiting may improve over several days. Your clinician will reassess benefit and safety within weeks. Treatment should be as short as possible. Long-term or repeated courses raise the risk of movement disorders and are generally avoided.

Comparar con alternativas

For reflux-related symptoms where acid suppression is preferred, a proton pump inhibitor such as omeprazol may be considered. For milder heartburn or when an H2 blocker is appropriate, famotidina is a common option. These medicines work by reducing stomach acid rather than increasing motility.

Precios y acceso

Explore Canadian pricing for metoclopramide with US delivery from Canada. Many patients compare metoclopramide price, check the cost of metoclopramide 10 mg tablets, and order metoclopramide online as a cash-pay option. If you are comparing brand and generic, review your prescription and select the approved product before checkout.

Ready to save on your metoclopramide cost? See current pricing on this page and complete secure checkout. For current offers, visit our promociones page. We provide prompt US delivery from Canada after prescription verification.

Disponibilidad y sustituciones

If a specific strength or form is temporarily unavailable, your prescriber may suggest an appropriate alternative or a different formulation. For occasional heartburn relief, some patients use OTC H2 blockers such as Pepcid® AC Fácil de Tragar, when suitable. Your clinician decides whether a substitution fits your condition.

Adecuación al paciente y consejos para ahorrar costes

Metoclopramide may suit adults with documented diabetic gastroparesis who need short-term symptom control. It is not suitable for people with GI obstruction, active GI bleeding, pheochromocytoma, or a history of tardive dyskinesia. Use special caution in older adults, people with seizure disorders, those with depression, and in Parkinson’s disease.

• Ask about the lowest effective dose for the shortest duration.
• Using the tablet form may be the most cost-effective option.
• Consider a multi-month supply if clinically appropriate to reduce per-shipment costs.
• Programa recordatorios de recarga para no quedarte sin nada durante el viaje.
• Keep your prescription information current so your order is not delayed.

For broader GI treatments, you can browse our trastornos gastrointestinales sección.

Preguntas para su médico

• Is metoclopramide appropriate for my diagnosis and symptoms?
• What dose and duration do you recommend for me?
• How will we monitor for movement side effects or mood changes?
• Could metoclopramide affect how my other medicines absorb?
• What signs mean I should stop the drug and call you?
• Are there non-drug options or alternative medicines I should consider?

Fuentes autorizadas

• FDA DailyMed: Metoclopramide
• FDA Label: Metoclopramide Tablets
• Base de datos de medicamentos de Health Canada

Start your metoclopramide order with Canadian pricing and US delivery from Canada. This content is for general information and does not replace your clinician’s advice or the official label.