Please note: a valid prescription is required for all prescription medication.
Abilify® is an atypical antipsychotic used for schizophrenia, bipolar I episodes, Tourette’s disorder, irritability linked to autism, and as an add-on for major depressive disorder. This page summarizes labeled uses, dosing basics, safety, and how to access it with US shipping from Canada, including options if you pay without insurance.
What Abilify Is and How It Works
This medicine contains aripiprazole, a dopamine D2 and serotonin 5‑HT1A partial agonist, and a 5‑HT2A antagonist. By modulating these pathways, it can help reduce hallucinations, delusions, agitation, and mood symptoms. It is taken once daily and can be used alone or with other therapies depending on the diagnosis.
CanadianInsulin connects patients with licensed Canadian pharmacies. Prescriptions are verified with your clinic before dispensing.
To learn more about condition-specific roles, see Abilify Uses.
Who It’s For
Aripiprazole is indicated for adults with schizophrenia and bipolar I disorder, and as adjunctive therapy for major depressive disorder. It is also approved for Tourette’s disorder and for irritability associated with autism in pediatric patients when a prescriber deems it appropriate. See related overviews for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder.
Do not use if you have a known allergy to aripiprazole or any component. It is not approved for dementia-related psychosis in elderly patients due to increased mortality risk. Discuss pregnancy, plans to become pregnant, and breastfeeding with your clinician. Tell your prescriber about diabetes, seizure history, cardiovascular disease, dehydration risk, impulse-control concerns, and any past movement disorders.
Dosage and Usage
Dosing is individualized by the prescriber based on the condition, age, and other medicines. It is typically taken once daily, with or without food, at the same time each day. For adjunctive use in depression, clinicians commonly start low and adjust at intervals to balance benefit and tolerability. Pediatric dosing is weight- and indication-specific; caregivers should follow the clinician’s written instructions.
Orally disintegrating tablets dissolve on the tongue; handle with dry hands and take immediately after opening. For the oral solution, measure doses with a marked syringe or cup, not a household spoon. Swallow tablets whole with water. Do not change your dose or stop suddenly without medical guidance, as symptoms can recur or worsen.
If switching between dosage forms, your prescriber will provide instructions. Keep all follow-up appointments so your response and side effects can be monitored, and labs obtained when indicated.
Strengths and Forms
Availability may vary. Common presentations include:
- Tablets: 2 mg, 5 mg, 10 mg, 15 mg, 20 mg, 30 mg
- Orally disintegrating tablets: 10 mg, 15 mg
- Oral solution: 1 mg/mL
Some strengths or forms may not be stocked at all times.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to the next one. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not double the dose. Set a daily reminder or use a pill organizer to support consistent timing.
Storage and Travel Basics
Store tablets and orally disintegrating tablets at room temperature in a dry place, away from moisture and direct heat. Keep ODT in the blister until use. Store the oral solution tightly closed as directed on the label and protect from light. Keep all medicines out of reach of children and pets.
When traveling, carry your medication in original packaging with your prescription details. Pack it in your carry-on to avoid temperature extremes. Bring a copy of your prescription or a clinic note for security checkpoints. If you cross time zones, align dosing to maintain roughly 24 hours between doses. Ask your clinician or pharmacist for trip-specific guidance if you are unsure.
Benefits
This treatment can help reduce hallucinations and delusions in schizophrenia. It may stabilize mood and reduce manic symptoms in bipolar I disorder. As an add-on for major depression, it can help improve mood and energy when initial antidepressant therapy is insufficient. Once-daily administration and multiple dosage forms offer flexibility. The orally disintegrating option can be useful when swallowing is difficult.
Side Effects and Safety
- Restlessness or inner jitteriness
- Sleepiness or insomnia
- Anxiety or agitation
- Nausea, vomiting, or constipation
- Dizziness or headache
- Weight gain or increased appetite
- Blurred vision or dry mouth
Serious but less common risks include neuroleptic malignant syndrome, tardive dyskinesia, stroke in elderly patients with dementia-related psychosis, significant changes in blood sugar or cholesterol, seizures, orthostatic hypotension, and trouble swallowing. There is a boxed warning for increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults when used with antidepressants. Impulse-control problems such as compulsive gambling or shopping can occur; report new urges promptly. Seek urgent care for high fever, severe muscle stiffness, confusion, uncontrolled movements, fainting, or signs of severe allergic reaction.
For a focused overview, see Abilify Side Effects.
Drug Interactions and Cautions
Tell your prescriber about all medicines and supplements. Strong CYP3A4 inhibitors (for example certain azole antifungals) or CYP2D6 inhibitors (for example some SSRIs) can increase aripiprazole exposure. Strong CYP3A4 inducers (for example certain anticonvulsants) can lower levels. Your prescriber may adjust therapy when these are used together. Alcohol and other sedatives can increase drowsiness. Use caution with medicines that affect blood pressure or cause dehydration. Avoid driving or operating machinery until you know how the medicine affects you.
What to Expect Over Time
Some people notice early changes in energy, sleep, or agitation, while core mood and thought symptoms may improve gradually. Consistent daily dosing supports steady effects. Your clinician may adjust the dose based on your response and tolerability. Keep a simple symptom log to discuss at visits. If benefits seem to fade or side effects emerge, contact your prescriber rather than stopping abruptly.
Compare With Alternatives
For schizophrenia or bipolar spectrum needs, prescribers may consider lurasidone, offered as Latuda. For depression management where augmentation is not needed, an SSRI such as Escitalopram may be used as primary therapy when appropriate. Choice depends on diagnosis, side effect profile, prior treatment, and individual goals discussed with your clinician.
Pricing and Access
See current options and check Abilify price through CanadianInsulin’s checkout. You can review brand and generic availability, compare cash-pay options, and place an order for US delivery from Canada after prescription verification. If you are looking for occasional discounts, visit our Promotions page for current offers. Checkout is encrypted to protect your information.
Availability and Substitutions
Brand and generic products may both be available. Stock changes over time. If a requested strength or form is temporarily unavailable, your prescriber may suggest a therapeutically appropriate alternative or a different presentation of aripiprazole. Talk with your clinician before accepting any substitution. For those comparing cross-border values, Aripiprazole Canadian pricing may differ from local pharmacy quotes.
Patient Suitability and Cost-Saving Tips
Good candidates are those with an approved indication who can take a daily oral medicine and keep follow-up visits. It may not be suitable for individuals with certain movement disorders, a history of neuroleptic malignant syndrome, or those at high risk for impulse-control problems without close monitoring. Discuss risks and benefits if you have diabetes, cardiovascular disease, or if you are pregnant or breastfeeding.
To manage out-of-pocket costs, ask your prescriber whether a multi-month supply is appropriate, as larger fills can reduce per-fill fees. Setting refill reminders helps prevent gaps that can lead to relapse. If you switch from brand to generic, confirm the same dosage form and strength to maintain consistency. Keep your clinic informed about all medicines to avoid duplicate therapy.
Questions to Ask Your Clinician
- Which indication are we targeting and how will we measure progress?
- What side effects should I watch for in the first few weeks?
- Could my other medicines interact with aripiprazole, including antidepressants or anticonvulsants?
- What should I do if I feel restless, excessively sleepy, or more anxious?
- Is an orally disintegrating tablet or the oral solution a better fit for me?
- How will this treatment plan change if I become pregnant or plan to breastfeed?
- What lab tests or check-ins do you recommend for long-term use?
Authoritative Sources
Pricing and Ordering Notes
Ready to proceed? Place your request and add your prescription; orders include verification and prompt processing with US delivery from Canada.
Note: Information here is educational and not a substitute for the FDA-approved or Health Canada labeling. Always follow your clinician’s directions and the package insert.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
How does aripiprazole differ from other antipsychotics?
Aripiprazole acts as a partial agonist at dopamine D2 and serotonin 5‑HT1A receptors and as a 5‑HT2A antagonist. This mechanism can balance neurotransmission rather than fully blocking dopamine. Clinically, that may mean different tolerability compared with some agents, but individual responses vary. Your clinician considers diagnosis, prior response, metabolic profile, movement risk, and coexisting conditions when selecting a therapy. Report any new or worsening symptoms promptly so the regimen can be reassessed if needed.
Can I take this medicine with antidepressants or mood stabilizers?
Yes, aripiprazole is often combined with antidepressants in major depressive disorder and may be used with mood stabilizers in bipolar disorder, when prescribed. Certain antidepressants (for example, fluoxetine or paroxetine) can raise aripiprazole levels through CYP2D6 inhibition, while some anticonvulsants can lower levels by inducing CYP3A4. Never adjust doses on your own. Share a complete medication list so your prescriber can manage potential interactions.
What are signs that side effects need urgent care?
Seek urgent help for very high fever, severe muscle stiffness, confusion, irregular heartbeat, uncontrolled movements, fainting, seizures, swelling of the face or throat, trouble breathing, or signs of severe allergic reaction. Call your clinician promptly for new or worsening restlessness, uncontrollable urges, suicidal thoughts, chest pain, or severe dizziness. Keep a list of emergency contacts and local urgent care options, especially when starting or changing therapy.
How should I take orally disintegrating tablets?
With dry hands, peel back the foil, remove the tablet carefully, and place it on your tongue. It dissolves quickly and can be swallowed with saliva. Do not push the tablet through the foil or store it outside the blister. Take it immediately after opening. Avoid splitting or chewing the ODT unless your clinician advises otherwise. If you need liquids to help swallow, plain water is fine. Keep ODT in its original packaging until use.
What monitoring might be needed during treatment?
Your clinician may track weight, waist circumference, blood pressure, fasting glucose or A1C, and lipids over time. They may also assess movement symptoms, restlessness, sleep changes, mood, and suicide risk, especially after dose adjustments. Bring a medication list and symptom notes to visits. Monitoring plans vary by age, condition, and coexisting health issues. Ask which tests apply to your situation and how often they are recommended.
Is it safe to drink alcohol while taking aripiprazole?
Alcohol can increase drowsiness, dizziness, and judgment impairment with aripiprazole. Combining them can also complicate the assessment of mood or anxiety symptoms. If you drink, discuss amounts and timing with your clinician. Avoid hazardous activities if you feel sedated or lightheaded. People with a history of substance use disorder should have a tailored plan that addresses alcohol and other substances during treatment.
What if I need to stop or switch therapies?
Do not stop suddenly unless directed by a clinician. Abrupt discontinuation can lead to symptom return or withdrawal effects. If a switch is needed, your prescriber will design a schedule that may involve gradual changes and close monitoring. Keep enough medicine on hand during transitions, and schedule follow-up to review progress and side effects. Report any new or severe symptoms immediately during a switch.
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