Jardiance

Jardiance (empagliflozin) is an oral medication used to improve blood sugar control in adults with type 2 diabetes. It works by helping the kidneys remove excess sugar through urine. Jardiance also lowers the risk of heart failure and cardiovascular events in people with type 2 diabetes and can assist in weight loss.

Benefits:

• Helps lower blood sugar levels in adults with type 2 diabetes
• Reduces the risk of cardiovascular death, heart attack, and stroke in people with type 2 diabetes
• Helps prevent the progression of heart failure
• Supports weight loss by reducing the amount of glucose reabsorbed by the kidneys
• Can be used alongside other diabetes medications for enhanced blood sugar control

Dosage:

For Type 2 Diabetes

• The typical starting dose is 10 mg once daily, preferably in the morning.
• Depending on individual needs, the dose may be increased to 25 mg once daily after 4-12 weeks of treatment.

For Heart Failure (with reduced ejection fraction)

• The recommended dose is 10 mg once daily. If tolerated, the dose can be increased to 25 mg once daily after at least 4 weeks.

For Chronic Kidney Disease (CKD)

• The usual dose is 10 mg once daily. If tolerated, the dose may be increased to 25 mg once daily.

Warnings and Precautions:

• Jardiance can cause dehydration, leading to low blood pressure, especially in elderly patients or those on diuretics.
• Use caution in patients with kidney impairment, as it can worsen kidney function.
• Jardiance may increase the risk of DKA, even without significantly high blood sugar levels.
• Jardiance increases the risk of urinary tract and genital infections, particularly in women.
• When used with insulin or sulfonylureas, it can increase the risk of hypoglycemia.
• Not recommended during pregnancy or breastfeeding. Consult a healthcare provider if pregnancy is planned.

Usage Instructions:

• Take Jardiance once daily, with or without food
• Take the tablet at the same time each day for consistency
• Swallow the tablet whole; do not crush, split, or chew
• If you miss a dose, take it as soon as you remember, unless it’s close to your next dose. Do not take two doses at once

Storage Information:

• Store Jardiance at room temperature, between 68°F to 77°F (20°C to 25°C)
• Keep the bottle tightly closed and out of reach of children
• Avoid storing in high humidity or in a bathroom

Common Side Effects:

• Some individuals may experience urinary tract infections (UTIs).
• Increased urination is a common side effect as the medication helps the body eliminate excess sugar.
• Yeast infections may occur, especially in the genital area.
• Dehydration can lead to dizziness or lightheadedness.
• Low blood pressure (hypotension) may be experienced, particularly when standing up quickly.
• Some people may feel tired or weak. 

More information about Jardiance

• Product Monograph – Health Canada
• U.S. Food and Drug Administration Medication Guide

Manufacturer: Boehringer Ingelheim

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