Jardiance (empagliflozin) Tablets

Jardiance is a prescription tablet containing empagliflozin, used to help manage blood sugar in adults with type 2 diabetes and for certain heart or kidney conditions. This page summarizes how the medicine works, typical strengths, safety considerations, and practical handling details to review with a prescriber. CanadianInsulin supports access with US shipping from Canada for people paying cash, including those without insurance.

What Jardiance Is and How It Works

This medicine belongs to a class called SGLT2 inhibitors (sodium-glucose cotransporter 2 inhibitors). These treatments lower blood glucose by helping the kidneys remove glucose through urine. That action can also cause a mild diuretic effect (more salt and water leaving the body), which is one reason the class is often discussed in cardiovascular and kidney care.

CanadianInsulin connects valid prescriptions to licensed Canadian pharmacies for dispensing.

Empagliflozin works mainly in the kidney’s proximal tubules, where SGLT2 proteins normally reabsorb glucose back into the bloodstream. By reducing reabsorption, more glucose is excreted. This may improve A1C and fasting glucose when paired with diet and activity changes that a clinician recommends. For background on the class, browse the SGLT2 Inhibitors hub or read the Empagliflozin Uses article.

Who It’s For

Empagliflozin is commonly prescribed for adults with Type 2 Diabetes to improve glycemic control, typically alongside lifestyle measures and sometimes other glucose-lowering medicines. Depending on current labeling and a person’s health history, a prescriber may also use it as part of treatment for Heart Failure. In some settings it may be considered for people with Chronic Kidney Disease, based on approved indications and renal function criteria.

This therapy is not used for type 1 diabetes, and it is not used to treat diabetic ketoacidosis (DKA). It may be unsuitable in people who are on dialysis, have had a serious allergic reaction to the drug, or have certain high-risk situations such as recurrent severe genital infections. Kidney function, blood pressure, hydration status, and other medicines are key factors in whether it is appropriate.

Why it matters: SGLT2 inhibitors can affect fluid balance, so baseline kidney and blood pressure status matters.

For broader context on how the drug class fits into cardiac care, see Changing Heart Failure Care.

Dosage and Usage

For adults, empagliflozin is typically taken by mouth once daily. Many regimens start with a lower strength and may be adjusted later based on treatment goals, kidney function, tolerability, and other medications. It can usually be taken with or without food, and many people take it in the morning to align with routine labs or to reduce nighttime urination.

Follow the directions on the prescription label, since dose selection depends on clinical factors. Jardiance is commonly started at 10 mg once daily and may be increased to 25 mg once daily when appropriate. If a dose is missed, labeling commonly advises taking it when remembered on the same day and not doubling the next dose.

Before and during therapy, clinicians may check kidney function (eGFR) and consider whether other medicines should be adjusted to reduce low blood sugar risk. If the medication is temporarily held around surgery, prolonged fasting, or acute illness, that decision should be guided by the prescriber because of ketoacidosis risk.

Strengths and Forms

This medication is supplied as oral tablets in two strengths: 10 mg and 25 mg. The generic name is empagliflozin; a true generic equivalent may or may not be available depending on market authorization and pharmacy sourcing. Packaging, tablet markings, and manufacturer details can vary by region and dispenser.

On this page, the most common presentation referenced is Jardiance 10 mg tablets; a 25 mg strength is also used in practice when prescribed. Availability can differ across pharmacies and wholesalers, and substitutions are not appropriate unless the prescriber authorizes them.

Quick tip: Keep a photo of the label and DIN/NDC for travel and refills.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep the bottle tightly closed, and leave tablets in their original container until needed. As with most prescription medicines, store out of reach of children and pets, and do not use tablets past the labeled expiration date.

For travel, carry tablets in a personal item rather than checked luggage to reduce exposure to temperature swings. Keep a copy of the prescription or pharmacy label available for security checks and emergency replacement. If a dose schedule changes because of time zones, that plan should be discussed with the prescriber rather than improvised.

If disposal is needed, follow local pharmacy take-back guidance or municipal medication disposal programs. Avoid flushing medicines unless specific instructions say to do so.

Side Effects and Safety

Because empagliflozin increases glucose in urine, the most common side effects involve the urinary and genital areas. Some people notice more frequent urination, thirst, or mild dehydration symptoms. Genital yeast infections and urinary tract infections can also occur, particularly in people with a history of these infections.

More serious risks are less common but important. Jardiance can be associated with ketoacidosis (a dangerous acid buildup) even when blood sugar is not extremely high, especially during prolonged fasting, heavy alcohol intake, severe illness, or around surgery. It may also contribute to low blood pressure or dizziness in people who are volume-depleted, older, or taking diuretics. Kidney problems can occur in certain settings, particularly with dehydration.

Recognizing serious symptoms

Seek urgent medical care for symptoms that could signal a severe reaction or complication. These include signs of ketoacidosis such as nausea, vomiting, abdominal pain, deep or rapid breathing, unusual sleepiness, or confusion. Also get prompt assessment for severe genital or perineal pain, redness, swelling, or fever, which can rarely indicate a serious infection. Any signs of anaphylaxis (severe allergic reaction) such as facial swelling, wheezing, or trouble breathing require emergency care. For possible kidney injury, watch for markedly reduced urination, swelling, or severe weakness.

Hypoglycemia (low blood sugar) is more likely when this therapy is combined with insulin or insulin secretagogues (medicines that stimulate insulin release). Clinicians may recommend monitoring plans that fit the broader diabetes regimen and personal risk factors.

Drug Interactions and Cautions

Drug interactions for empagliflozin are often about additive effects rather than a direct chemical interaction. Medicines that increase urination (such as loop or thiazide diuretics) can raise the chance of dehydration and low blood pressure when combined with an SGLT2 inhibitor. Blood pressure medicines may also contribute to lightheadedness in some people, particularly when starting treatment.

Insulin and sulfonylureas can increase the risk of low blood sugar when used together with glucose-lowering therapies. Any changes to those medicines should be made by a clinician. Tell the prescriber about over-the-counter products and supplements, since illness remedies, laxatives, or weight-loss agents can affect fluid status.

Extra caution is often needed for people with reduced kidney function, frequent urinary infections, low-carbohydrate diets, heavy alcohol intake, or planned surgery. If sick-day rules are used in a diabetes plan, they should be reviewed with the care team and aligned with current prescribing information.

Compare With Alternatives

Several medicines treat type 2 diabetes and may also have cardiovascular or kidney-related indications. Within the same drug class, alternatives include dapagliflozin and canagliflozin. Some people use a DPP-4 inhibitor (such as sitagliptin) when an SGLT2 inhibitor is not appropriate, though the risk/benefit profile differs across classes.

Differences between options can involve approved indications (diabetes vs heart failure vs kidney disease), kidney function cutoffs, side effect patterns, and how they fit with other therapies like metformin, insulin, or GLP-1 receptor agonists. For product listings related to the SGLT2 class, see Farxiga Dapagliflozin and Invokana 100 mg 300 mg. For non-class background reading, the guide Januvia Uses can help clarify how DPP-4 inhibitors differ.

Choice of therapy should reflect the prescriber’s goals for A1C, heart failure status, kidney function, and tolerability, rather than a one-size-fits-all approach.

Pricing and Access

Out-of-pocket pricing for prescription medicines can vary based on dose, supply length, dispensing pharmacy, and whether a person uses private insurance or Medicare drug coverage. Formularies may require prior authorization or step therapy, and copays can differ across plans. Some patients explore manufacturer assistance programs or third-party savings options where available.

Jardiance access through CanadianInsulin is typically structured as a cash-pay pathway with prescription verification when required. If a discount program is relevant, visit Promotions for currently listed offers and eligibility details. For a broader view of diabetes therapy options that may affect budgeting and selection discussions with a clinician, browse Non Insulin Medications.

When required, prescriptions are confirmed with the prescriber before dispensing proceeds.

Authoritative Sources

For the most reliable and current details, use official prescribing information and regulator-backed references. These sources summarize indications, dosing limits, contraindications, and warnings, and they are updated when new safety information emerges. A pharmacist or prescriber can help interpret them for an individual clinical situation.

Neutral references that may be helpful include:

• Prescribing details on DailyMed: U.S. National Library of Medicine (DailyMed)
• Regulatory approval summaries: U.S. FDA Drugs@FDA Database
• Patient-friendly medication overview: MedlinePlus

For practical education about related therapies, CanadianInsulin also maintains topic guides such as Farxiga Used For. Those articles complement, but do not replace, official labeling.

To submit a request, upload a valid prescription and select prompt, express, cold-chain shipping if it is offered for your order.

This content is for informational purposes only and is not a substitute for professional medical advice.