What is Nesina (Alogliptin)?
Nesina is a prescription medication that works as adipeptidyl peptidase-4 (DPP-4) inhibitor.This medication is often prescribed along with exercise and a healthy diet to control blood sugar levels. Nesina is a product of Takeda Pharmaceuticals.
What is it used for?
Nesina is only indicated for the treatment of type 2 diabetes. The drug is intended to be used in combination with other non-pharmacological interventions such as exercise and dietary modification. This medication is only intended for adult patients more than 18 years of age.Ensure to provide your doctor with your complete medical history prior to treatment. Nesina should not be used by patients with type 1 diabetes or diabetic ketoacidosis, a condition that causes increased ketones in the urine or blood.
How to take this medication
Do not use more (or less) than the prescribed amount. Do not change the dose of Nesina without consulting the doctor. If you are taking a lower dose of this medication and do not notice an improvement in your symptoms, tell your doctor. Do not stop taking this medication, even if you are feeling better. This medication can be taken with or without food and should be taken once daily.
How does this drug work?
Nesina contains alogliptin as its active ingredient. DPP-4 inhibitors such as alogliptin can reverse the actions of insulin-reducing DDP-4 enzymes, helping to increase insulin release into the bloodstream. At the same time, alogliptin reduces postprandial and fasting glucose concentration in a glucose-dependent manner.
Dosage
Nesina comes in three dose strengths: 6.25mg, 12.5mg and 25mg. All tablets are film-coated andoval-shaped.
To treat type II diabetes, it is recommended to take 25mg of Nesina once a day (with or without food).The drug can be used as amonotherapyor combination therapy. While taking Nesina, the dose of insulin secretagogues (e.g.sulfonylureas) or insulin should be reduced to prevent hypoglycemia.
The dose of Nesina needs to be adjusted based on renal function. While taking the drug, patients who have renal impairments should undergoexamination of renal function periodically.Inthe case of moderate renal impairment, use half of the recommended daily dose(12.5 mg). In patients with severe renal impairment, it is recommended to use 6.25 mg of Nesina once per day.During each trimester of pregnancy, the doctor may prescribe a different dose of Nesina. Similarly, the dose may need to be adjusted in breastfeeding patients.
Your doctor will determine the appropriate dose based on your condition and reaction to treatment. Follow your doctor’s instructions.
Side effects
- Headache
- Stuffy nose
- Sinus pain
- Sore throat
Nesina on its own is unlikely to cause hypoglycemia, a condition where the blood sugar is dangerously low. Please note that this is not a complete list of all the possible side effects of Nesina. The drug may cause side effects other than the ones listed here.As a general rule, patients are advised to see a doctor if side effects persist or worsen. If patients have any questions about the side effects of Nesina, they should consult a doctor.
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