Please note: a valid prescription is required for all prescription medication.
Tradjenta® (linagliptin) is an oral DPP-4 inhibitor for adults with type 2 diabetes. This page helps compare Tradjenta 5 mg tablets price and lets you order online from Canada with US delivery from Canada. Some patients pay cash without insurance.
CanadianInsulin connects patients with licensed Canadian pharmacies. Prescriptions are verified with your clinic before dispensing.
What Tradjenta® Is and How It Works
Tradjenta® is indicated to improve glycemic control in adults with type 2 diabetes, along with diet and exercise. It belongs to the dipeptidyl peptidase-4 (DPP-4) inhibitor class. Inhibiting DPP-4 slows the breakdown of incretin hormones, such as GLP-1 and GIP. These hormones help the pancreas release insulin when glucose is elevated and reduce glucagon secretion. The result is support for both fasting and post-meal glucose control.
The medicine is taken by mouth and can be used alone or with other antihyperglycemics. Common combinations include metformin, SGLT2 inhibitors, thiazolidinediones, or insulin when clinically appropriate. For a quick overview of options, see Oral Diabetes Medications.
Who Tradjenta® Is For
Use in adults with type 2 diabetes to improve glycemic control as an adjunct to diet and exercise. Tradjenta is not indicated for type 1 diabetes or for the treatment of diabetic ketoacidosis. Safety and effectiveness in pediatric patients have not been established.
Those with a history of pancreatitis, severe hypersensitivity to linagliptin, or bullous skin disorders should review risks with a clinician before starting therapy. Individuals with heart failure or kidney disease should consider overall treatment goals and monitoring. For condition-focused browsing, visit the Type 2 Diabetes category.
Dosage and Usage
The usual adult dose is 5 mg once daily, with or without food. Tablets should be swallowed whole. Consistent daily timing supports adherence. When combined with a sulfonylurea or insulin, the risk of hypoglycemia increases; prescribers may adjust background agents. Renal or hepatic impairment typically does not require a dose change per labeling. For context on labeled dosing, see Tradjenta Dose.
Tradjenta can be used as monotherapy or as add-on to other agents when additional A1C reduction is needed. Clinicians determine the mix of diet, activity, and medicines based on clinical history, A1C targets, and potential side effects.
Strengths and Forms
- Tradjenta 5 mg tablets
- Linagliptin 5 mg tablets
Film-coated tablets are supplied in various pack sizes. Availability may vary by pharmacy and manufacturer.
Missed Dose and Timing
If a dose is missed, take it when remembered the same day. If it is almost time for the next dose, skip the missed dose. Do not take two doses at once. Establishing a daily routine, such as taking the tablet with breakfast, may help keep dosing consistent.
Storage and Travel Basics
Store your tablets at room temperature, typically 20°C to 25°C, with brief excursions permitted per the label. Keep the bottle tightly closed and protected from moisture. Do not store in a bathroom. For trips, keep your medication in original packaging in your carry-on. Bring your prescription details and clinic contact information to support travel screening and refills if needed.
Benefits
- Once-daily 5 mg dosing is simple to follow.
- Glucose-dependent mechanism lowers hypoglycemia risk when used without insulin or sulfonylureas.
- Weight-neutral profile reported in clinical studies.
- Usable as monotherapy or add-on to other diabetes medicines.
- No routine renal dose adjustment per labeling.
These features support individualized A1C goals when combined with diet and physical activity.
Side Effects and Safety
Common side effects can include:
- Nasopharyngitis, cough, or sore throat
- Headache or back pain
- Diarrhea
- Joint pain
Serious or less common risks include pancreatitis, severe allergic reactions including angioedema, bullous pemphigoid, and severe joint pain. Stop the medicine and seek prompt medical care for symptoms of pancreatitis (such as severe abdominal pain), signs of a serious allergic reaction, or blistering skin lesions. Hypoglycemia can occur, especially when used with insulin or sulfonylureas. Additional information is available in Side Effects Tradjenta.
Drug Interactions and Cautions
- Strong inducers of CYP3A4 and P-gp, such as rifampin, may reduce linagliptin exposure.
- Concomitant use with insulin or a sulfonylurea elevates hypoglycemia risk.
- Review history of pancreatitis, bullous skin disease, or serious hypersensitivity before initiation.
- Consider monitoring when heart failure is present.
Always evaluate the full medication list, including over-the-counter products and herbals such as St. John’s wort. A pharmacist or clinician can assess interaction risks in the context of the full regimen.
What to Expect Over Time
Some improvement in daily blood glucose may be seen early, with A1C assessed over months. Stable daily use, regular glucose checks as directed, and lifestyle measures support durable control. If targets are not reached, prescribers may adjust background therapy or consider adding another class.
Compare With Alternatives
Other approved options for type 2 diabetes include therapies from the DPP-4, biguanide, SGLT2, GLP-1, and insulin classes. Within DPP-4 inhibitors, sitagliptin is a commonly used peer; an overview is provided in Differences Tradjenta Vs Januvia.
Two alternatives available through our service include Januvia® and the extended-release metformin product Glumetza®. Selection depends on clinical history, A1C goals, and tolerance of prior therapies. Discuss the role of each agent in a complete treatment plan.
Pricing and Access
Canadian pricing may lower the Tradjenta 5 mg tablets price compared with typical US cash rates. Check Tradjenta US shipping options and see the current Tradjenta 5 mg price on this page. You can buy Tradjenta 5 mg online and select US delivery from Canada at checkout. For reference, many shoppers look for Tradjenta cash price, linagliptin 5 mg price, and Tradjenta 5 mg cost before placing an order. Compare the Tradjenta price from Canada before checkout.
You can order Tradjenta online in a few steps after the prescription is received. Tradjenta ships to US addresses with prompt US delivery from Canada. For seasonal deals, visit our Promotions. Checkout is encrypted.
Availability and Substitutions
Supply can vary by pharmacy and package size. If a requested item is unavailable, a prescriber may recommend a suitable alternative. Some patients ask about generic linagliptin 5 mg; availability differs by market and should be confirmed with the prescriber and dispensing pharmacy.
Patient Suitability and Cost Saving Tips
- Not for type 1 diabetes or treatment of diabetic ketoacidosis.
- Avoid in anyone with known hypersensitivity to linagliptin.
- Discuss risks with a history of pancreatitis or bullous pemphigoid.
- No routine dose adjustment for renal impairment per label; follow clinical guidance.
- Multi-month fills can reduce per-unit cost and cut pharmacy fees.
- Set refill reminders in your account to prevent gaps in therapy.
- Keep tablets in original bottles during travel for easier screening and identification.
Questions to Ask Your Clinician
- How does linagliptin fit with current A1C goals and background therapy?
- Is add-on therapy with metformin, an SGLT2 inhibitor, or basal insulin appropriate now?
- What signs of pancreatitis or severe allergy require urgent care?
- Are any medicines in the regimen CYP3A4 or P-gp inducers that could lower exposure?
- How often should glucose be checked and A1C reassessed?
- Is a multi-month supply suitable to streamline refills and reduce per-fill costs?
Authoritative Sources
Start your order for Tradjenta 5 mg with US delivery from Canada.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
What is Tradjenta 5 mg and how does it work?
Tradjenta (linagliptin) 5 mg is an oral DPP-4 inhibitor for adults with type 2 diabetes. It raises incretin levels, which increase insulin release in a glucose-dependent way and lower glucagon. This helps reduce fasting and post-meal glucose when used with diet and exercise.
How is Tradjenta usually taken?
The labeled dose is 5 mg once daily, with or without food. Tablets are swallowed whole. When used with a sulfonylurea or insulin, hypoglycemia risk rises and clinicians may adjust the background agent. Follow the official label and prescriber directions.
Can Tradjenta be used with metformin or other diabetes medicines?
Yes. Linagliptin can be used alone or with other agents such as metformin, SGLT2 inhibitors, thiazolidinediones, or insulin when appropriate. The specific combination depends on clinical goals and tolerability.
What if a dose of Tradjenta is missed?
If a dose is missed, take it when remembered the same day. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not double up doses.
Does Tradjenta cause low blood sugar?
When used alone, DPP-4 inhibitors have a low risk of hypoglycemia. The risk increases when combined with insulin or a sulfonylurea. Monitor glucose as directed by the clinician.
Is Tradjenta suitable in kidney disease?
Per labeling, no routine dose adjustment is needed for renal impairment. Clinicians consider overall kidney function, comorbidities, and background therapy when planning treatment.
How should Tradjenta tablets be stored?
Store at room temperature, typically 20°C to 25°C, protected from moisture, and keep the bottle tightly closed. For travel, keep medication in original packaging and in a carry-on bag.
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