Januvia® Tablets for Type 2 Diabetes

Januvia® is a sitagliptin tablet used to support blood sugar control in adults with type 2 diabetes. This page explains how it works, key safety information, and how to access it with US delivery from Canada. You can also review options for Januvia 100 mg without insurance.

What Januvia Is and How It Works

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Januvia belongs to the DPP-4 inhibitor class. It helps increase incretin hormones, which can raise insulin release and lower glucagon when glucose levels are elevated. This medicine works throughout the day and can be used alone or with other diabetes therapies such as metformin, sulfonylureas, SGLT2 inhibitors, or insulin. A Januvia 100 mg tablet is typically taken once daily as part of an overall care plan that includes diet and physical activity.

It is not approved for type 1 diabetes or diabetic ketoacidosis. The treatment may be continued long term if tolerated and effective, as determined by your healthcare professional. For background on the class, see Januvia Drug Class and Oral Diabetes Medications.

Who It’s For

This therapy is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. It may suit people who need an oral, once-daily option and who are not achieving goals with lifestyle measures alone. It can be used as monotherapy or with other agents when combination therapy is appropriate.

It is not for patients with type 1 diabetes, diabetic ketoacidosis, or known hypersensitivity to sitagliptin. People with a history of pancreatitis should discuss risks with a clinician. Those with kidney impairment require careful review of the label, as dosage adjustments may be needed.

Dosage and Usage

The usual recommended schedule is one tablet taken once daily with or without food, at the same time each day. Swallow tablets whole with water. If you are also prescribed insulin or a sulfonylurea, your prescriber may monitor for low blood sugar and adjust other therapies as needed.

Read the official label for complete dosing directions, including adjustments in renal impairment. A Sitagliptin 100 mg tablet is the commonly used adult dose for those with normal kidney function. Do not split, crush, or chew the tablets unless the official instructions explicitly allow it. Keep consistent meal patterns to support stable glucose measurements.

Strengths and Forms

Tablets are available in several strengths to match individual needs. Market availability can vary by country and pharmacy.

• 25 mg film-coated tablets
• 50 mg film-coated tablets
• 100 mg film-coated tablets

Labeling and packaging differ by market. Your prescriber will specify the appropriate strength. A Sitagliptin phosphate 100 mg tablet may not be suitable for all patients; follow the official label and your prescriber’s guidance.

Missed Dose and Timing

If you miss a dose, take it when you remember the same day. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. Consistency helps maintain steady control, so consider reminders or a daily routine.

Storage and Travel Basics

Store tablets at room temperature in the original blister or bottle. Protect from excessive moisture and light. Keep out of reach of children and pets. Do not use after the expiration date on the package.

When traveling, keep the medication in your carry-on bag with a copy of your prescription. Maintain the product in its labeled container for security screening. If crossing borders, bring documentation for your medicines. Pack a small supply of snacks or glucose tablets if you also take therapies that can lower blood sugar.

Benefits

This medicine can improve fasting and post-meal glucose when taken as directed. It is taken once daily, which may fit many routines. When used alone, it generally has a low risk of hypoglycemia. The treatment is weight neutral for many users, according to label and clinical data.

It can be combined with metformin or other oral agents when needed. For comparisons within the class, you can review Difference Linagliptin Vs Sitagliptin and Linagliptin Vs Januvia.

Side Effects and Safety

• Upper respiratory tract infection
• Nasopharyngitis
• Headache
• Cough or sore throat
• Stomach discomfort

Serious but less common risks include pancreatitis, severe joint pain, hypersensitivity reactions, and bullous pemphigoid. Stop the medicine and seek urgent care if you develop severe abdominal pain, a widespread rash, or swelling of the face or throat. When used with insulin or sulfonylureas, the risk of hypoglycemia can increase. Read the Medication Guide for a full list of warnings and precautions.

Drug Interactions and Cautions

Sitagliptin can interact with digoxin; monitoring may be considered. Concomitant use with insulin or insulin secretagogues may require closer glucose monitoring due to hypoglycemia risk. Inform your healthcare professional about all medicines you take, including over-the-counter products and supplements. Patients with renal impairment should review the official label for dosing and monitoring guidance.

What to Expect Over Time

Effects on blood sugar typically appear as you take doses consistently and follow your plan for diet and activity. Your clinician may monitor A1C and fasting glucose during routine visits. If you start combination therapy, they may review symptoms of low blood sugar and discuss how to treat it if it occurs.

Adherence matters. Take the tablet at the same time each day and keep follow-up appointments. Maintain a log of home glucose readings if recommended. If you experience new symptoms such as persistent abdominal pain or a severe rash, contact your prescriber promptly.

Compare With Alternatives

Other DPP-4 inhibitors include linagliptin and saxagliptin. We offer Tradjenta and Onglyza. Combination products pairing sitagliptin with metformin are also available; see our article Januvia Vs Janumet for an overview. Interest in “Generic for Januvia 100 mg” is common, but actual market availability depends on jurisdiction and timing.

Pricing and Access

Compare current options and see how Canadian pharmacy pricing works with your prescription. We facilitate access with transparent checkout and encrypted payment. If you are researching the Januvia 100 mg price, you can view the product page for current offers. We provide Ships from Canada to US service for eligible orders.

Looking for a coupon? See our Promotions page for current site-wide opportunities when available. For broader context on therapies used with this class, explore Type 2 Diabetes and Oral Insulin Medications.

Availability and Substitutions

Supply can vary by strength and pack size. If a strength is temporarily unavailable, a prescriber may recommend a suitable alternative in the same class or a different class, based on your clinical profile. We cannot guarantee restock dates.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults who prefer once-daily tablets, have type 2 diabetes, and need an add-on or initial oral option. It may not be appropriate for people with a history of pancreatitis or significant kidney disease unless the prescriber determines benefits outweigh risks. Review all safety details on the official label.

• Plan refills early to avoid gaps
• Ask about multi-month fills if appropriate
• Use reminders to support adherence
• Track glucose trends to share at visits
• Confirm any lab monitoring your clinician recommends

Questions to Ask Your Clinician

• Is this class suitable given my medical history?
• How should I monitor for hypoglycemia with my other medicines?
• What signs of pancreatitis require urgent care?
• Do I need kidney function tests before and during therapy?
• How does this fit with my diet and activity plan?
• Should I continue metformin or other agents with this?

Authoritative Sources

FDA DailyMed: Sitagliptin

Manufacturer: Merck – Januvia

Health Canada DPD: Sitagliptin

Ready to proceed? Place your order for US shipping from Canada with prompt, express, temperature-controlled handling when required. This information is not a substitute for medical advice; always follow your prescriber and the official label.