Cosopt® Eye Drops for Open-Angle Glaucoma

Cosopt® is a prescription eye drop that combines dorzolamide and timolol to lower pressure in open-angle glaucoma or ocular hypertension. It helps reduce fluid production inside the eye, which may protect the optic nerve. This page explains how it works, safety guidance, and ways to compare options with US delivery from Canada, including what Cosopt eye drops price without insurance can depend on.

What Cosopt Is and How It Works

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This medicine contains two active ingredients. Dorzolamide is a carbonic anhydrase inhibitor that reduces aqueous humor formation. Timolol is a beta blocker that also decreases aqueous humor production. Together, the treatment can lower intraocular pressure when used as directed. It may be prescribed when a single agent does not provide adequate pressure control or when a fixed combination is preferred by your prescriber.

The drops are for topical ocular use only. They are not a substitute for follow-up examinations. Your clinician may combine this therapy with other classes if needed, based on your response and tolerability.

Who It’s For

This treatment is indicated for patients with open-angle glaucoma or ocular hypertension who need additional pressure lowering. It is generally used in adults. People with active asthma, severe chronic obstructive pulmonary disease, certain heart rhythm disorders, heart block without a pacemaker, or overt heart failure should not use timolol-containing eye drops. Anyone with a sulfonamide allergy should discuss risks because dorzolamide is a sulfonamide derivative.

For planning, we reference Dorzolamide Timolol ophthalmic solution price later in the pricing section so you can compare options with your prescriber.

Dosage and Usage

The usual schedule is one drop in the affected eye or eyes twice daily, morning and evening. Wash your hands. Tilt your head back and gently pull down the lower eyelid to form a pocket. Hold the bottle above the eye without touching the tip to any surface. Instill one drop, then close your eyes and press the inner corner of the eyelid for 1 to 2 minutes to reduce systemic absorption. If you use other eye medications, separate them by at least five minutes, using gels and ointments last.

Remove soft contact lenses before using the multi-dose formulation and wait 15 minutes before reinsertion. Avoid touching the tip to the eye or eyelids. If the solution changes color or becomes cloudy, do not use it. Follow the official label and your prescriber’s instructions for specific guidance.

Strengths and Forms

This therapy is available as an ophthalmic solution in multi-dose bottles and as a preservative-free unit-dose presentation. The commonly published fixed combination contains dorzolamide 2% and timolol 0.5%. The preservative-free format comes in single-use vials designed to be opened immediately before administration and discarded after use.

Unit-dose vials can be helpful if you are sensitive to preservatives. For those comparing formats, Cosopt PF eye drops price varies by package size and supply duration.

Missed Dose and Timing

If you miss a dose, instill it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not double the drops to make up for a missed dose. Consistent twice-daily use supports steady pressure reduction.

Storage and Travel Basics

Store the bottle at room temperature in a dry place and keep it tightly closed. Protect from contamination and keep out of reach of children. Do not freeze. For preservative-free vials, open immediately before use and discard after single application. When traveling, pack the drops in your carry-on, keep them in original packaging with your prescription label, and avoid extreme temperatures. Temperature-controlled handling when required helps maintain product quality during transit.

Benefits

This combination brings two pressure-lowering mechanisms together in one bottle. Using a fixed combination can simplify routines compared with separate bottles, which may support adherence. The class can be used alongside other glaucoma agents if directed by your clinician. Many patients prefer a fixed-dose option when monotherapy is insufficient.

Side Effects and Safety

• Temporary burning or stinging
• Blurred vision right after instillation
• Bitter or unusual taste
• Dry eyes or tearing
• Eyelid irritation
• Headache

Serious effects are uncommon but can occur. Beta blockers may cause slow heart rate, low blood pressure, worsening heart block, or bronchospasm, especially in people with airway disease. Dorzolamide, a sulfonamide, may rarely trigger severe skin reactions. Corneal edema can occur in individuals with preexisting corneal compromise. If you experience breathing difficulties, dizziness, fainting, swelling, severe rash, or vision changes, seek medical help promptly.

Drug Interactions and Cautions

Use caution if you take systemic beta blockers, calcium channel blockers, digoxin, clonidine, or antiarrhythmics, as additive effects on heart rate and blood pressure may occur. Combining multiple topical beta blockers is not recommended. Avoid combining multiple carbonic anhydrase inhibitors without clinician oversight. Inform your healthcare professional if you have kidney or liver disease, diabetes, thyroid disorders, or myasthenia gravis. Remove soft contact lenses before instillation of multi-dose formulations that contain benzalkonium chloride.

What to Expect Over Time

Intraocular pressure lowering is typically observed with regular use. Your clinician will monitor eye pressure and optic nerve findings over time and may adjust your regimen. Keep a simple routine, use reminders, and bring your bottle to visits so your provider can review technique. Report bothersome symptoms, especially breathing changes or slow heart rate, and any new ocular irritation or redness that does not resolve.

Compare With Alternatives

Some patients respond well to a carbonic anhydrase inhibitor alone such as Trusopt®, or to a beta blocker alone such as Timolol Maleate Ophthalmic Solution. Others may use a prostaglandin analogue as first-line therapy; if further reduction is needed, clinicians may add a second agent or switch to a fixed combination. You can also buy dorzolamide timolol eye drops online with a valid prescription through our platform.

Pricing and Access

We list current supply options and formats to help you compare, including multi-dose bottles and preservative-free vials. Factors like vial count, bottle size, and brand or generic status influence Cosopt eye drops cost. You can review available packages and compare out-of-pocket totals with US shipping from Canada. If you use insurance, check your plan; many people also compare cash-pay scenarios. For savings updates, see our Promotions page.

Availability and Substitutions

Supply can vary by formulation and packaging. If a particular presentation is unavailable, your prescriber may consider a generic fixed-dose alternative or separate single agents. We also provide Dorzolamide Ophthalmic Solution and other glaucoma therapies when appropriate. For people comparing presentations, Dorzolamide Timolol 2%/0.5% price information helps frame expectations across formats. Any switch should be guided by your clinician to maintain pressure targets.

Patient Suitability and Cost-Saving Tips

People with airway disease, certain cardiac conditions, or sulfonamide allergy may not be candidates for this combination. Patients with mild ocular surface sensitivity sometimes consider preservative-free vials. To reduce costs, ask about multi-month supplies, compare generic options, and set up refill reminders. Consider combining eye care appointments with medication refills to keep your regimen consistent. If you track Dorzolamide timolol eye drops price over time, note that market changes and supply can affect posted figures.

Questions to Ask Your Clinician

• Primary goal: target pressure and optic nerve protection
• Fit with current regimen: add-on vs switch
• Technique check: instillation and punctal occlusion
• Lens guidance: timing with contact lenses
• Safety review: heart, lungs, and sulfonamide allergy
• Follow-up plan: timing for pressure checks
• Travel plan: packing and documentation

Authoritative Sources

DailyMed: Dorzolamide-Timolol Ophthalmic SolutionHealth Canada Drug Product DatabaseFDA DailyMed Index

Some patients also discuss prostaglandin analogues with their clinician; see Vyzulta® Ophthalmic Solution for one option and learn more about risk factors in Diabetic Eye Disease Month. For pediatric eye safety topics, explore Children’s Eye Health.

Ready to proceed? You can start your order online. Ships from Canada to US with prompt shipping. This information is not a substitute for professional medical advice; always follow your prescriber’s directions and the official label.