Edecrin® Tablets for Edema and Fluid Retention

Edecrin® (ethacrynic acid) is a prescription loop diuretic for edema caused by heart failure, kidney disease, or liver cirrhosis. This page explains safe use and helps compare Edecrin 25 mg tablets with Canadian pricing and US delivery from Canada. You can view Edecrin price without insurance and place an order from Canada that ships to the US.

What Edecrin® Is and How It Works

Edecrin is a potent loop diuretic. It increases urine output by blocking sodium and chloride reabsorption in the ascending loop of Henle. This removes excess fluid and reduces swelling and shortness of breath linked to congestive heart failure, kidney disease, or cirrhosis. Unlike many loop diuretics, ethacrynic acid is not a sulfonamide.

At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.

Edecrin is used when rapid and effective diuresis is needed. Clinicians may choose it for patients who cannot take sulfonamide-containing diuretics. It is taken by mouth as tablets. Your prescriber sets the dose and schedule based on your condition and response.

Who Edecrin® Is For

Edecrin treats edema due to congestive heart failure, renal disease (including nephrotic syndrome), and cirrhosis. It may be used when other diuretics are not tolerated or are insufficient. Learn more about the condition on our Edema page.

Do not use if you cannot make urine (anuria) or if you have severe dehydration or marked electrolyte depletion. Use caution with kidney impairment, liver disease with encephalopathy risk, hearing problems, low blood pressure, or a history of gout. Children and older adults require special care due to higher risk of side effects. Discuss pregnancy and breastfeeding considerations with your clinician.

For heart failure background, see Entresto Dose Recommendations.

Dosage and Usage

Follow your prescription exactly. Typical oral initiation for adults is 50 mg once, then adjust as needed. Some patients start at 25 mg, especially if frail or at risk of low blood pressure or electrolyte loss. The dose may be increased by 25 to 50 mg based on diuretic response and tolerability. Many patients take 50 to 200 mg per day in one or two divided doses. The lowest effective dose is preferred. A maximum total daily dose is used only under close supervision.

Take tablets with food if stomach upset occurs. Drink fluids as instructed by your prescriber. Monitor weight daily. Report rapid weight changes, dizziness, or muscle cramps. Regular blood tests are often ordered to check potassium, sodium, magnesium, kidney function, and uric acid.

Strengths and Forms

Edecrin is supplied as oral tablets. Commonly published strength:

• 25 mg tablets (ethacrynic acid 25 mg tablet)

Availability may vary. Some clinicians may use divided doses to reach the prescribed daily total. Intravenous ethacrynate sodium exists for inpatient use, but outpatient therapy is commonly with Edecrin 25 mg tablets.

Missed Dose and Timing

If you miss a dose, take it when remembered unless it is close to the next scheduled dose. If it is close, skip the missed dose. Do not double the next dose. To reduce nighttime urination, take a once-daily dose in the morning. If taking twice daily, the second dose is often mid-afternoon.

Storage and Travel Basics

Store tablets at room temperature in a dry place, ideally 20 to 25°C (68 to 77°F). Keep the bottle closed tightly and away from moisture and direct light. Do not store in the bathroom. For travel, keep Edecrin in your carry-on, in the original labeled container. Bring a copy of your prescription. Avoid leaving medicine in a hot car.

Benefits

Edecrin reduces swelling in the legs, abdomen, and lungs by removing excess salt and water. This may ease shortness of breath and improve mobility and comfort. As a non-sulfonamide loop diuretic, it may be an option for patients who cannot take other loop diuretics. It is available as oral tablets, which many patients find convenient for home use under a clinician’s guidance.

Side Effects and Safety

• Frequent urination
• Dizziness or lightheadedness
• Headache
• Stomach upset, nausea, or diarrhea
• Muscle cramps or weakness
• Thirst and dry mouth
• Low blood pressure on standing
• Skin rash

Serious effects can include dehydration, low potassium, low sodium, low magnesium, kidney function changes, gout flares, and rare hearing changes or tinnitus. Ototoxicity risk increases with very high doses or when combined with other ototoxic drugs. Seek urgent care for fainting, severe weakness, confusion, hearing loss, ringing in the ears, or a severe rash.

Drug Interactions and Cautions

• Aminoglycosides or cisplatin: higher ototoxicity risk
• Digoxin: low potassium increases toxicity risk
• Lithium: increased lithium levels and toxicity risk
• NSAIDs: may reduce diuretic effect and impact kidneys
• Other antihypertensives: additive blood pressure lowering
• Other diuretics or laxatives: greater electrolyte loss
• Corticosteroids: may worsen potassium loss
• High-dose salicylates: enhanced toxicity risk

Tell your clinician and pharmacist about all medicines, vitamins, and herbal products. Use caution with kidney or liver impairment, diabetes, gout, and hearing issues. For kidney-focused therapy context, see Kerendia Uses.

What to Expect Over Time

Diuresis often starts within hours of a dose. Swelling and weight may decrease over days to weeks as your prescriber adjusts the dose. Blood pressure may lower modestly. Routine lab checks guide safe dosing. Report symptoms of dehydration, cramps, or dizziness promptly. If hearing changes occur, contact your clinician right away and seek evaluation.

For additional heart failure education, you may read Dapagliflozin Heart Failure.

Compare With Alternatives

Loop and related diuretics vary in potency, duration, and tolerability. Two common alternatives include:

• Furosemide: a loop diuretic often used for edema in heart failure and kidney disease.
• Spironolactone: an aldosterone antagonist frequently used for cirrhosis-related ascites and as add-on therapy in heart failure.

Your prescriber will select a regimen based on your condition, kidney function, and response.

Pricing and Access

CanadianInsulin provides transparent Edecrin price information with Canadian pricing and US delivery from Canada. Many customers compare Edecrin cost, Edecrin tablet price, and Edecrin price from Canada before checkout. You can Buy Edecrin online and Order Edecrin tablets once your prescription is verified. We also display ethacrynic acid price and ethacrynic acid 25 mg tablet options when available.

Customers using self-pay can review Edecrin price without insurance, Edecrin cash price, and Edecrin US shipping details in the cart. We support Edecrin ships to US ordering with secure payment. You can also Buy ethacrynic acid or Order ethacrynic acid tablets if prescribed for the same indication. For additional savings tips, see our Promotions. Encrypted checkout helps protect your information.

This page functions as an Edecrin online pharmacy referral listing with Edecrin Canadian pricing. It also helps compare ethacrynic acid cost and ethacrynic acid 25 mg tablets when your clinician prescribes that option.

Availability and Substitutions

Product availability can change. If a specific strength is unavailable, your prescriber may recommend a different strength or a therapeutic alternative. Do not substitute or change your dose without clinical guidance.

Patient Suitability and Cost Saving Tips

Edecrin may suit adults with clinically significant edema who need a loop diuretic and who cannot tolerate other options. It may not suit patients with anuria, severe dehydration, or profound electrolyte depletion. People with hearing problems, gout, or advanced kidney or liver disease require careful monitoring.

• Ask your clinician about a multi-month supply if appropriate
• Use one pharmacy to help coordinate refills and labs
• Set reminders for daily dosing and timely refills
• Track weight and symptoms to support dose decisions
• Keep lab appointments to avoid preventable side effects

Questions to Ask Your Clinician

• What daily dose and timing should I use for Edecrin?
• How often should I check electrolytes, kidney function, and weight?
• What symptoms mean I should call the clinic right away?
• Can I combine Edecrin with potassium supplements or other diuretics?
• Do I need a specific sodium or fluid plan while on this medicine?
• Could my other medicines increase ototoxicity or dehydration risk?
• Is a multi-month supply appropriate for my treatment plan?

Authoritative Sources

• DailyMed: Edecrin (ethacrynic acid)
• Health Canada Drug Product Database
• FDA: Orange Book Listings

Start your Edecrin checkout with US delivery from Canada.