Diflucan® 150 mg Tablet for Vaginal Candidiasis

Fluconazole is an antifungal medicine for Candida infections, including vaginal yeast infections. This page covers how it works, safety basics, and ordering steps with US shipping from Canada, even without insurance.

What Fluconazole Is and How It Works

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Fluconazole is a triazole antifungal that inhibits fungal 14‑alpha demethylase, a cytochrome P450–dependent enzyme. By reducing ergosterol synthesis, this medicine disrupts the fungal cell membrane and limits growth. It is active against many Candida species and is used for mucosal and systemic candidiasis when indicated.

The generic is therapeutically equivalent to Diflucan®. It is absorbed well by mouth, reaches tissue and cerebrospinal fluid, and is eliminated primarily by the kidneys. Labeling describes use for vaginal candidiasis, oropharyngeal and esophageal candidiasis, cryptococcal meningitis, and for prevention of Candida infections in certain immunocompromised patients.

Who It’s For

Approved uses include uncomplicated and complicated vaginal candidiasis, oropharyngeal candidiasis (thrush), esophageal candidiasis, cryptococcal meningitis, and prophylaxis against Candida infections in selected patients at risk. A prescriber determines suitability based on diagnosis, severity, and medical history.

People with known hypersensitivity to this class should avoid it. Use in pregnancy is generally avoided for non–life‑threatening infections; prescribers may consider it only when potential benefit justifies potential risk. The drug appears in human milk; discuss breastfeeding considerations with a healthcare professional. Patients with significant liver disease, known QT prolongation, or those taking certain QT‑prolonging drugs require careful evaluation. For background on why yeast infections can be more frequent with diabetes, see Diabetes Yeast Infections.

Dosage and Usage

Follow your prescription label. Swallow tablets with or without food. For oral suspension, shake well and use a marked dosing device.

Uncomplicated vaginal candidiasis is often treated as a Fluconazole 150 mg single dose, as directed by labeling and your prescriber. Other indications typically require a defined course, sometimes starting with a loading dose followed by a maintenance schedule. Therapy length depends on site and response. Do not stop early unless instructed by a clinician.

Renal function influences dosing frequency; clinicians adjust per the official label. If symptoms persist or worsen, contact a healthcare professional rather than taking extra doses.

Strengths and Forms

• Tablets: commonly available in 50 mg, 100 mg, 150 mg, and 200 mg strengths. Availability can vary by manufacturer.
• Oral suspension powder for reconstitution: Fluconazole oral suspension 10 mg/mL and 40 mg/mL presentations are published in labeling.

Actual supplied strength and pack size may vary by manufacturer and market.

Missed Dose and Timing

If a scheduled dose is missed, take it when remembered unless it is close to the next dose. If it is nearly time for the next dose, skip the missed dose. Do not double doses. For single‑dose therapy, take the dose as soon as possible if missed. If vomiting occurs shortly after dosing, consult a clinician for advice on whether to repeat a dose.

Storage and Travel Basics

Store according to the product label. Tablets are typically kept at controlled room temperature in a closed container away from moisture. Reconstituted suspension is commonly stable for a limited time; follow the pharmacy label for beyond‑use dating. Keep out of reach of children.

When traveling, keep medicines in original labeled packaging and carry a copy of the prescription. Pack doses in your carry‑on and allow extra time for security screening. For extended trips, discuss refills in advance and carry a list of current medications. Use a dedicated measuring device for liquid dosing while away from home.

Benefits

This treatment can be taken by mouth and reaches many tissues, including cerebrospinal fluid. The single‑dose option for vaginal candidiasis is convenient in appropriate cases. A defined dosing schedule supports adherence, and the medicine is widely used under established guidelines. Suspension offers an option for patients who have difficulty swallowing tablets.

Side Effects and Safety

• Headache
• Nausea or stomach pain
• Diarrhea or dyspepsia
• Dizziness
• Rash or pruritus

Serious effects are uncommon but can include liver problems, severe skin reactions, anaphylaxis, and effects on heart rhythm (QT prolongation). Stop the medicine and seek medical care for symptoms of liver injury (dark urine, jaundice, severe fatigue), severe rash, rapid or irregular heartbeat, or facial swelling. The drug can raise sulfonylurea exposure; patients using those agents have a higher risk of hypoglycemia and need monitoring. Learn more about background therapies at Common Diabetes Medications.

Drug Interactions and Cautions

Fluconazole is a strong inhibitor of CYP2C9 and CYP2C19 and a moderate inhibitor of CYP3A4. Important interactions include warfarin (increased INR/bleeding risk), certain sulfonylureas (low blood sugar risk), phenytoin, carbamazepine, cyclosporine, tacrolimus, some benzodiazepines (sedation), certain statins, and others. Enzyme inducers such as rifampin can lower fluconazole levels.

Avoid combining with contraindicated QT‑prolonging agents such as cisapride or pimozide. Use caution with other medicines that affect cardiac conduction. Clinicians often check baseline hepatic function for prolonged courses and adjust dosing in renal impairment. Alcohol does not have a specific labeled interaction but may compound hepatic risks; discuss intake with a clinician.

What to Expect Over Time

Symptom improvement depends on the infection site, organism, and immune status. Single‑dose vaginal candidiasis regimens may provide gradual relief, while other indications can require longer courses under supervision. Continue therapy as prescribed, even as symptoms improve. For patients with diabetes, addressing glucose control may help reduce recurrence risk; see Manage Yeast Infections. Contact a healthcare professional if symptoms persist or return.

Compare With Alternatives

Topical azole creams are common for localized skin infections but are not always suitable for systemic or mucosal disease. For dermatomycoses, allylamines such as Terbinafine may be used for skin and nail infections per clinical guidance. Azole topicals like Ketoconazole can be appropriate for certain superficial infections when a clinician recommends a topical approach.

Pricing and Access

View current options, compare strengths, and see potential savings with Canada‑sourced rates and US shipping from Canada. For those paying cash, the Fluconazole 150 mg price depends on strength, quantity, and manufacturer. Check the latest site listings for available pack sizes and dispensing pharmacies.

See limited‑time offers on our promotions page: Promotions. Orders are processed through an encrypted checkout after prescription validation when required.

Availability and Substitutions

Supply can vary by manufacturer, strength, or dosage form. When a specific pack is unavailable, a prescriber may suggest a therapeutically equivalent strength or a different antifungal option when appropriate. Generic labeling and bottle appearance may differ by pharmacy.

Patient Suitability and Cost-Saving Tips

• Who may benefit: patients with confirmed Candida infections, per diagnosis and label.
• Who may not: those with severe hepatic disease, problematic QT prolongation, or azole hypersensitivity.
• Medication review: share current prescriptions, over‑the‑counter drugs, and supplements before starting therapy.
• Multi‑month planning: for longer regimens, consolidating refills may reduce per‑fill fees when appropriate.
• Set reminders: use calendar alerts to support adherence during extended courses.
• Budgeting: if you pay out of pocket, compare strengths and pack sizes to find a suitable option discussed with a clinician.

Questions to Ask Your Clinician

• Is this infection likely caused by Candida species susceptible to this therapy?
• What course length is typical for my diagnosis, and how will progress be assessed?
• Which medicines should be paused or adjusted to avoid interactions?
• Do I need baseline or follow‑up liver function tests during treatment?
• What side effects should prompt contacting your office right away?
• Is a topical option reasonable for my symptoms, or is oral therapy preferred?
• How should I handle dosing around travel or time‑zone changes?

Authoritative Sources

• Pfizer Diflucan Prescribing Information (US)
• DailyMed: Fluconazole
• Health Canada Drug Product Database

Start your order at CanadianInsulin for express, US shipping from Canada; temperature-controlled handling when required. This information is not a substitute for medical advice. Always follow the official label and your prescriber’s guidance.