Itrafungol® Oral Solution for Feline Ringworm

What Itrafungol Is and How It Works

Itrafungol is an itraconazole oral antifungal for cats with dermatophytosis (ringworm), typically caused by Microsporum canis. This page explains how the medicine works, how to give it, and what safety points to know. Access for US shipping from Canada can help you compare options, including paying without insurance.

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Itrafungol® belongs to the triazole class. It inhibits fungal ergosterol synthesis by blocking the 14α-demethylase enzyme, which weakens the fungal cell membrane. The itrafungol oral solution is flavored for palatability and is given with a dosing syringe directly into the cat’s mouth.

Ringworm is a contagious skin infection. Alongside this treatment, veterinarians often recommend environmental cleaning to reduce reinfection risk and shorten recovery.

Who It’s For

This medicine is indicated for cats diagnosed with dermatophytosis due to susceptible organisms. Kittens may be candidates when a veterinarian confirms the diagnosis and considers age, weight, and overall health. Use itrafungol for cats only under veterinary supervision.

Do not use in animals with known hypersensitivity to itraconazole or other azole antifungals. Use caution in cats with liver disease, pregnancy, or nursing. It is not approved for use in dogs; any cross-species use should be veterinarian-directed.

Dosage and Usage

Follow your veterinarian’s instructions exactly. A commonly used schedule for this class is once daily in cycles (for example, a week on therapy followed by a week off), repeated as directed. The specific itrafungol dosage depends on weight and clinical status. Your veterinarian may adjust the duration based on clinical response or fungal culture results.

Administration tips:

• Measure carefully with the supplied oral syringe; avoid kitchen spoons.
• Give the dose into the cheek pouch to reduce drooling and spitting out.
• If stomach upset occurs, ask your veterinarian whether dosing with a small snack is appropriate.
• Complete the entire course even if skin looks improved early.

Because this solution contains itraconazole at a defined concentration, dosing volume is weight-based. Your vet may monitor liver enzymes during longer courses to support safe use.

Strengths and Forms

This product is supplied as a flavored oral liquid for cats. Availability can vary by pharmacy and jurisdiction.

• Concentration: itrafungol 10 mg ml oral solution
• Common bottle size: may be supplied in multi-dose bottles suitable for a full course

Packaging sizes (such as 52 mL) can differ by market. Your fill size will depend on your prescribed duration and your cat’s weight.

Missed Dose and Timing

If you miss a dose, give it when you remember unless it is close to the next scheduled dose. If it is almost time for the next dose, skip the missed one and resume the regular schedule. Do not double doses. If multiple doses are missed, contact your veterinarian for guidance.

Storage and Travel Basics

Store the bottle tightly closed at controlled room temperature as indicated on the label. Keep it upright and protect it from excessive heat and direct light. Do not freeze. Keep out of reach of children and other animals.

For travel, carry the bottle in original packaging with the prescription label. Pack the dosing syringe in a clean bag. Keep the medicine in your hand luggage if flying, and avoid leaving it in a hot car. Bring a copy of your veterinarian’s directions if crossing borders with your pet.

Benefits

Triazole antifungals target fungal cell membranes, which can help resolve ringworm lesions when part of a complete management plan. Once-daily schedules and a palatable liquid can aid adherence for many cats. Cyclic dosing schedules may reduce caregiver burden while maintaining effectiveness under veterinary supervision.

Side Effects and Safety

Common effects may include:

• Gastrointestinal upset such as vomiting or soft stools
• Reduced appetite or drooling after dosing
• Lethargy or transient behavior changes
• Mild skin or coat changes while lesions heal

Rare but serious risks include liver issues, severe vomiting, yellowing of the gums or eyes, or unusual bleeding. Stop the medicine and contact your veterinarian if you observe worrisome signs. Because azoles can affect liver enzymes, periodic bloodwork may be recommended. Avoid concurrent drugs that prolong QT interval or strongly affect CYP3A pathways unless your veterinarian approves and monitors therapy. Discuss the itrafungol side effects profile with your veterinarian before starting.

Drug Interactions and Cautions

Itraconazole can interact with drugs metabolized by CYP3A. Examples include certain macrolide antibiotics, some sedatives, and selected antiarrhythmics. Antacids or acid suppressants may alter absorption; ask your veterinarian before combining therapies.

Use caution with pre-existing liver disease. Report all supplements and over-the-counter products your cat receives. Do not start or stop other medicines without veterinary guidance.

What to Expect Over Time

Skin lesions may improve gradually over several weeks. Hair regrowth can lag behind clinical clearing. Your veterinarian may recommend rechecks or fungal cultures to confirm control. Consistent dosing, environmental cleaning, and avoiding contact between infected and uninfected pets can support outcomes.

Do not discontinue early without veterinary advice, even if patches look resolved. Recurrence can occur if treatment stops too soon or if environmental spores persist.

Compare With Alternatives

Some veterinarians may select other systemic antifungals based on patient factors, culture results, or prior response. Two common options are ketoconazole and terbinafine. If your vet recommends an alternative, you can review related options such as Ketoconazole or Terbinafine. Do not substitute without veterinary approval.

Pricing and Access

Canadian pricing may offer value for US pet owners. You can compare total costs, including consultation and monitoring needs, before you place an order. Ships from Canada to US for eligible prescriptions. For current offers, see Promotions. Checkout uses industry-standard encryption.

To explore broader veterinary categories, visit Feline Ringworm resources and browse Pet Medications for related therapies.

Availability and Substitutions

Supply can vary. If the prescribed product is unavailable, your veterinarian may recommend a clinically appropriate alternative. In selected cases, a branded terbinafine may be considered; see Lamisil for background on that active ingredient. Changes should remain veterinarian-directed.

Patient Suitability and Cost-Saving Tips

This treatment may suit otherwise healthy cats with confirmed dermatophytosis. It may not be ideal for cats with significant liver disease or for pregnant or nursing queens unless a veterinarian decides benefits outweigh risks.

• Multi-month fills: Ask whether one shipment can cover the full course.
• Refill reminders: Set calendar prompts to avoid missed doses.
• Bundle care: Plan culture checks or re-exams to avoid extra trips.
• Environmental care: Follow cleaning guidance to reduce reinfection risk.

For topical adjuncts in people or household decontamination planning, veterinarians may discuss human antifungal options; see Ketoderm for an example of ketoconazole topical used in humans. Do not use human creams on pets unless your veterinarian advises.

Questions to Ask Your Clinician

• Diagnosis confirmation: Do we need a fungal culture or Wood’s lamp exam?
• Dosing plan: What schedule and duration are planned for my cat?
• Monitoring: Will bloodwork be checked during therapy?
• Interactions: Are any current medicines a concern with itraconazole?
• Home measures: What cleaning steps reduce environmental spores?
• Rechecks: When should we reassess or repeat cultures?

Authoritative Sources

For detailed product information, review these official resources:

• FDA CVM: Itrafungol Oral Solution FOI Summary (NADA 141-400)
• FDA: Product page for Itraconazole Oral Solution for Cats
• Health Canada Drug Product Database: Search itraconazole veterinary entries

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