Kerendia® Tablets for Chronic Kidney Disease in Type 2 Diabetes

Kerendia® is a prescription tablet used to help protect kidneys and the heart in adults with chronic kidney disease linked to type 2 diabetes. This page explains what it does, who it suits, and how to use it safely. You can also review access options, including the Kerendia cost without insurance, with US delivery from Canada.

What Kerendia Is and How It Works

Kerendia® contains finerenone, a nonsteroidal mineralocorticoid receptor antagonist. It helps block harmful overactivation of mineralocorticoid receptors in the kidneys and heart. This action may reduce scarring and inflammation, supporting kidney function and lowering cardiovascular risk in appropriate adults with type 2 diabetes and chronic kidney disease.

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This medicine is taken by mouth once daily. It can be used alongside standard-of-care therapies for diabetes and blood pressure, such as ACE inhibitors or ARBs, when appropriate. Clinicians monitor potassium and kidney function to guide dosing and ongoing safety.

Who It’s For

This treatment is indicated to reduce the risk of sustained kidney function decline, end-stage kidney disease, cardiovascular death, nonfatal heart attack, and hospitalization for heart failure in adults with chronic kidney disease associated with type 2 diabetes. It is used as part of a broader plan that includes glucose and blood pressure control.

People with high baseline potassium, severe kidney impairment below labeled thresholds, or severe liver problems may not be candidates. Do not use with strong CYP3A4 inhibitors. Your care team will evaluate potassium levels and estimated glomerular filtration rate (eGFR) before starting therapy.

If you have chronic kidney disease, you can read more about the condition in our category guide on Chronic Kidney Disease. For diabetes context, see Type 2 Diabetes.

Dosage and Usage

The tablet is taken once daily, with or without food, at the same time each day. Swallow whole with water; do not crush or split. Avoid grapefruit or grapefruit juice, which can increase drug levels.

Before the first dose, clinicians check serum potassium and eGFR. Typical starting doses depend on kidney function. Those with better kidney function may start at the higher tablet strength, while those with reduced function may start lower. Potassium is rechecked about four weeks after initiation or dose changes, and dosing may be adjusted, held, or resumed based on results.

Do not start if your potassium is above the labeled threshold. Do not alter your prescribed regimen without discussing changes with your clinician. If uncertainty exists, defer to the official prescribing information.

Strengths and Forms

This medicine is available as oral tablets in commonly used strengths of 10 mg and 20 mg. Tablet imprinting and packaging may vary by manufacturer and pharmacy. Availability can vary by stock and jurisdiction.

Both tablet sizes are film-coated for once-daily dosing. Your prescriber will choose the strength based on kidney function and potassium levels. Pharmacy inventory and packaging presentation may differ across regions.

Missed Dose and Timing

If you miss a dose, take it the same day when you remember. If it is nearly time for the next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. Keeping a daily reminder can support adherence.

Storage and Travel Basics

Store tablets at room temperature in a dry place. Keep the bottle tightly closed and protect it from excess moisture. Keep out of reach of children and pets.

When traveling, carry the medication in your hand luggage in the original labeled container. Bring a copy of your prescription and a medication list. Pack an extra small supply when possible, and avoid storing tablets in hot cars or bathrooms.

For nephrology-related therapies and supplies, explore the Nephrology category for broader context.

Benefits

This class can help slow kidney disease progression in adults with type 2 diabetes and chronic kidney disease. It may also reduce the chance of cardiovascular complications, including hospitalization for heart failure, when used appropriately and monitored.

Once-daily dosing and tablet formulation support consistent use. Monitoring of potassium and kidney function helps tailor ongoing treatment decisions.

Side Effects and Safety

• High potassium (hyperkalemia) with or without symptoms
• Low blood pressure, dizziness, or lightheadedness
• Changes in kidney function tests
• Low sodium levels
• Gastrointestinal discomfort

Serious risks include clinically significant hyperkalemia that may require dose adjustment, temporary interruption, or discontinuation. Severe kidney impairment or volume depletion can increase risk of adverse effects. Seek urgent care for symptoms such as muscle weakness, palpitations, severe dizziness, or fainting. People taking insulin or sulfonylureas should watch for low blood sugar symptoms from their diabetes medications.

Learn about causes and warning signs in our article on Hyperkalemia Signs. For potassium balance context, see Hypokalemia vs Hyperkalemia.

Drug Interactions and Cautions

Do not use with strong CYP3A4 inhibitors, such as certain azole antifungals and macrolide antibiotics, which can markedly raise drug exposure. Avoid strong CYP3A4 inducers, which can lower exposure. Moderate CYP3A4 inhibitors may require additional caution and monitoring.

Concomitant use with potassium supplements or other potassium-sparing agents, including certain diuretics, may increase hyperkalemia risk. Use caution with trimethoprim and nonsteroidal anti-inflammatory drugs in susceptible patients. Avoid grapefruit or grapefruit juice. People with severe hepatic impairment may require careful consideration.

What to Expect Over Time

Clinicians typically monitor potassium and kidney labs within the first month and at intervals thereafter. Many people continue their background therapies for diabetes and blood pressure during treatment.

Expect qualitative changes rather than immediate symptoms. Keeping scheduled lab checks and taking the tablet as directed are key. For broader lifestyle and care planning, read our guide on Managing Diabetes.

Compare With Alternatives

Some patients with type 2 diabetes and chronic kidney disease may also be candidates for SGLT2 inhibitors alongside standard care. An example is Jardiance, which has kidney and cardiovascular data in diabetes care. In certain cases, clinicians use an angiotensin receptor blocker such as Irbesartan as part of foundational therapy to reduce proteinuria and protect kidney function.

Choice of therapy depends on medical history, lab results, and other medications. Your prescriber will advise whether an additional or alternative option is suitable.

Pricing and Access

Check the Kerendia 20 mg tablets price in the product options before placing an order. Pricing can vary by strength, quantity, and pharmacy dispensing.

Orders are fulfilled by licensed Canadian pharmacies with US shipping from Canada. You can view current pricing and compare your out-of-pocket needs. If you are seeking offers, see our Promotions page. We use encrypted checkout to help protect your information.

Availability and Substitutions

Stock may vary by strength and packaging. If an item is temporarily unavailable, your prescriber may recommend a comparable therapy suited to your condition. For country-specific information and supply notes, some customers review the Kerendia price Canada when discussing options with their care team.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with type 2 diabetes and chronic kidney disease who meet labeled lab thresholds and can commit to periodic potassium checks. It may not suit those with recurrent hyperkalemia, advanced kidney impairment outside the labeled range, or those on interacting medications that cannot be changed.

To manage expenses, consider multi-month quantities when appropriate, set refill reminders, and coordinate lab visits with refill dates. If you pay cash, you can compare the Kerendia cash price with alternative strengths and pack sizes. Ask your clinician whether tablet size choices align with your lab goals and monitoring plan.

Questions to Ask Your Clinician

• Starting criteria: Are my eGFR and potassium levels appropriate to start?
• Lab plan: How often will you check potassium and kidney labs?
• Drug interactions: Which medicines or supplements should I pause or avoid?
• Diet: Should I adjust dietary potassium or salt intake?
• Sick-day rules: What should I do during illness or dehydration?
• Therapy mix: Should I also use an SGLT2 inhibitor or an ARB?

Authoritative Sources

For complete prescribing details, see the FDA-approved Prescribing Information (official label) on the FDA website; it provides indications, dosing, and safety data. FDA Prescribing Information

The manufacturer site offers additional patient and professional resources about finerenone. Manufacturer Information

Health Canada’s Drug Product Database lists authorization and product details relevant to Canadian dispensing. Health Canada DPD

Ready to proceed? You can place your order with prompt, express shipping with temperature-controlled handling when required. Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.