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Komboglyze

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Komboglyze is a prescription medication used to manage type 2 diabetes. It combines saxagliptin (a DPP-4 inhibitor) and metformin (a biguanide) to help control blood sugar levels by increasing insulin production and decreasing glucose production in the liver. It is typically used alongside diet and exercise to improve glycemic control.

Benefits:

  • Combines two medications for more effective blood sugar control.
  • Helps lower A1C levels without causing significant weight gain.
  • Reduces glucose production in the liver and improves insulin sensitivity.
  • Can be taken with meals to help prevent blood sugar spikes.
  • May have a lower risk of hypoglycemia compared to some other diabetes medications.

Dosage:

  • Take twice daily with meals, as prescribed by your doctor.
  • Dosage is individualized based on blood sugar levels and kidney function.
  • Do not exceed the recommended daily dose.

Warnings and Precautions:

  • Not for use in type 1 diabetes or diabetic ketoacidosis (DKA).
  • May increase the risk of lactic acidosis, especially in patients with kidney problems.
  • Use with caution if you have a history of pancreatitis or heart failure.
  • Inform your doctor if you have liver disease, kidney disease, or alcohol use disorder.
  • Avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis.

Usage Instructions:

  • Take with food to reduce stomach discomfort.
  • Swallow whole with a full glass of water.
  • Do not skip doses—take consistently for best results.
  • Monitor blood sugar levels regularly as directed by your doctor.
  • Do not stop taking Komboglyze without consulting your healthcare provider.

Storage Information:

  • Store at room temperature (20°C to 25°C).
  • Keep in a dry place, away from moisture and heat.
  • Keep out of reach of children.

Common Side Effects:

  • Nausea, diarrhea, or stomach discomfort.
  • Headache or dizziness.
  • Upper respiratory infections (cold-like symptoms).
  • Low blood sugar (if taken with other diabetes medications).
  • Unusual tiredness or muscle pain (seek medical attention if severe).

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