Nobivac® Canine 1-DAPPv Vaccine for Dogs

Nobivac® Canine 1-DAPPv is a core vaccine for dogs and puppies. This page explains the DAPPv vaccine for dogs, how it is used, and how to access Canadian pricing with US delivery from Canada. Many pet owners pay cash without insurance, and this option is available here. Orders ship from Canada and arrive in the US using prompt, express, cold-chain shipping for temperature-sensitive products.

CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order.

What Nobivac® Canine 1-DAPPv Is and How It Works

Nobivac Canine 1-DAPPv is a Merck Nobivac Canine 1-DAPPv vaccine containing modified live canine distemper virus, adenovirus, parvovirus, and parainfluenza. This Canine DAPPv vaccine helps reduce the risk of severe illness from these common pathogens. It elicits protective antibodies and cellular immunity after the primary series and boosters. The adenovirus component (CAV-2) also helps protect against canine hepatitis caused by CAV-1. This DAPPv dog vaccine is part of core immunization plans recommended by many veterinarians.

Owners may see it described as a Nobivac 5 way DAPPv, referring to coverage across four viruses with cross-protection to hepatitis. It is designed for use in healthy dogs, including growing puppies, when administered on an approved schedule.

Who Nobivac® Canine 1-DAPPv Is For

This vaccine is indicated for the vaccination of healthy dogs and puppies against distemper, adenovirus, parvovirus, and parainfluenza. It is widely used as a DAPPv puppy vaccine to start early protection during the socialization window. Healthy adult dogs also benefit from periodic revaccination, as advised by the prescribing veterinarian and local protocols.

Do not administer to animals that are ill, febrile, immunocompromised, or known to be hypersensitive to vaccine components. Vaccination of pregnant or nursing bitches is generally not recommended unless the label and veterinarian specifically advise it. Only vaccinate clinically healthy animals.

Dosage and Usage

Nobivac Canine 1-DAPPv is supplied as a lyophilized product with sterile diluent. Reconstitute immediately before use and administer the entire 1 mL dose as directed on the label. Use aseptic technique and approved needles. Do not split doses between animals.

Puppy series: veterinarians commonly begin the series at about 6 to 8 weeks of age. Doses are repeated at intervals, often every 3 to 4 weeks, through at least 16 weeks of age. The final puppy dose timing can vary by clinic policy, regional risk, and label. Adult dogs: a booster dose is given as advised by the label and the prescribing veterinarian.

Follow the product insert and your clinic’s protocol. Most clinics coordinate DAPPv with other core care such as deworming, parasite control, and wellness exams.

Strengths and Forms

Common presentations include single-dose (1 mL) vials with a separate sterile diluent. Practices often order cartons such as Nobivac Canine 1-DAPPv 25×1 dose to cover a season’s caseload. Single-dose vials may also be available for individual dogs. Product availability can vary, and packaging is subject to change by the manufacturer.

This formulation is sometimes referred to as a Nobivac 1 DAPPv single dose or a Nobivac 5 way DAPPv vaccine. Clinics may pair DAPPv with leptospirosis coverage when risk is present, or they may use a combined DAPPv L4 series when appropriate.

Missed Dose and Timing

If a scheduled booster is delayed, the prescribing veterinarian should advise the next step. The plan may continue from the last valid dose or be restarted, depending on the dog’s age, interval, and risk. Immunity develops over time after the primary series and recommended boosters.

Storage and Travel Basics

Refrigerate vaccine vials as directed on the label and protect them from light. Do not freeze. Reconstitute immediately before use and discard any unused portion after administration. Do not save partially used or reconstituted vials for later.

When your order arrives, store your vaccine at controlled refrigerator temperatures per the label. If you need to bring your order to the clinic, keep your vaccine cold during travel with an insulated container and ice packs. Dispose of used syringes and needles responsibly according to local regulations.

Benefits

• Core protection against distemper, adenovirus, parvovirus, and parainfluenza.
• Proven, widely used DAPPv for puppies and adult dogs.
• Flexible scheduling that aligns with common veterinary protocols.
• Single-dose vials help maintain sterility and dosing accuracy.
• Canadian pricing with US shipping supports budget planning for clinics and owners.

Side Effects and Safety

• Temporary soreness or swelling at the injection site.
• Mild fever, lower activity, or reduced appetite for a day or two.
• Occasional sneezing or coughing with intranasal vaccines; this product is injectable, so respiratory signs are uncommon.
• In puppies, mild self-limiting reactions may occur as the immune system responds.

Serious reactions are rare but can include hypersensitivity, facial swelling, hives, collapse, or anaphylaxis. Immediate veterinary attention is required if severe signs appear. As with all vaccines, a small number of animals may not develop adequate protection even after a complete series.

Drug Interactions and Cautions

Concurrent immunosuppressive therapy (for example, systemic corticosteroids or other immune-modulating drugs) can reduce the response to vaccination. Vaccination should be postponed in sick or febrile animals. Use with other vaccines on the same day should follow the label and the veterinarian’s guidance. Only vaccinate healthy dogs. Keep to approved routes and dosage.

What to Expect Over Time

Protection builds after the primary series and recommended boosters. Puppies need a series to account for waning maternal antibodies. Adults typically receive periodic boosters to maintain protective immunity. Individual response may vary based on age, health status, and exposure risk. Many clinics bundle core vaccines with parasite prevention and wellness care to support overall health; for example, deworming options such as Droncit For Cats And Dogs Effective Tapeworm Treatment may be discussed separately.

Compare With Alternatives

Some clinics use a similar presentation designed for ease of administration, such as Nobivac® Canine Edge 1 Dappv. For very young dogs that only need distemper and parvovirus during early visits, Nobivac® Puppy Dpv can be considered by the prescribing veterinarian. Clinics may also add a separate leptospirosis vaccine when regional risk warrants broader protection.

Pricing and Access

See current Nobivac Canine 1-DAPPv price information on this page when available. Canadian pricing with US shipping can lower out-of-pocket costs for clinics and pet owners who purchase without insurance. Add to cart to view options and proceed through secure checkout. For broader pet medication choices, browse Pet Medications.

Orders are fulfilled with US delivery from Canada. Checkout is encrypted to protect payment details.

Availability and Substitutions

Stock status can vary. If the preferred presentation is unavailable, clinics may consider similar DAPPv options or adjust pack sizes. Some practices pair DAPPv with leptospirosis for risk-based coverage; if needed, see Nobivac® Canine Lepto 4 as a complement. Other alternatives include Nobivac Canine EDGE 1-DAPPv or Nobivac Puppy DPV as directed by the veterinarian.

Patient Suitability and Cost Saving Tips

Best candidates are clinically healthy puppies and adult dogs without fever or active illness. The vaccine is generally not recommended for pregnant bitches. Dogs with a history of severe vaccine reactions or current immunosuppressive therapy require individualized plans.

To manage costs, clinics sometimes choose larger cartons such as Nobivac Canine 1-DAPPv 25×1 dose when appropriate. Single-dose purchases remain practical for individual dogs. Planning visits around the Nobivac 1 DAPPv schedule can reduce extra trips. Pet owners paying cash without insurance often benefit from Canadian pricing with US delivery.

Pet health is a long-term plan. Learn more about other canine therapies in articles like Apoquel For Dogs Uses Benefits And Side Effects and Canine Diabetes Treatment Humulin N Insulin For Dogs Guide. These topics are separate from vaccination but can help owners understand broader care plans.

Questions to Ask Your Clinician

• What DAPPv schedule will you recommend for this dog’s age and risk?
• Should leptospirosis be added to DAPPv in this region?
• How will you manage vaccine intervals if a booster is delayed?
• What side effects are most likely in this patient, and when should I call?
• Are other core or non-core vaccines indicated for travel, boarding, or daycare?
• Will immunosuppressive medications affect vaccine response?

Authoritative Sources

• Merck Animal Health — Nobivac Canine Vaccines
• Merck Animal Health — Dog Products

Ready to proceed? Add Nobivac Canine 1-DAPPv to cart for US delivery from Canada.

Disclaimer: For veterinary use only. Follow the label and the prescribing veterinarian’s directions. Availability, pack sizes, and labeling may change without notice.