Nobivac® Canine Edge 1-DAPPv Vaccine for Dogs

Nobivac Canine Edge 1-DAPPv® is a core canine vaccine that helps protect dogs against distemper, adenovirus type 2, parainfluenza, and parvovirus. This page explains what it is, how it is used, and how to order it with US delivery from Canada. You can check price and cost details online, including potential savings without insurance.

Every CanadianInsulin order is prescription-checked with your clinic and dispensed by a licensed Canadian pharmacy.

What Nobivac® Is and How It Works

Nobivac Canine Edge 1-DAPPv is a veterinary vaccine indicated for the vaccination of healthy dogs. It contains modified live virus components for canine distemper virus, canine adenovirus type 2, canine parainfluenza virus, and canine parvovirus. The vaccine helps the immune system recognize these viruses so the dog can develop protective immunity.

The Edge presentation is designed as a low-volume dose. Many clinics prefer smaller-volume injections for comfort. This product is typically administered subcutaneously after reconstitution with the supplied diluent. For US pet owners, this product ships from Canada with prompt, cold-chain handling.

Who Nobivac® Is For

This vaccine is intended for healthy dogs, including puppies and adults, as part of a core vaccination program. Core vaccines help protect against widespread and potentially severe diseases. Puppies, unvaccinated adult dogs, and dogs with unknown vaccine history are common candidates.

Do not vaccinate dogs that are clinically ill, febrile, severely immunocompromised, or known to be hypersensitive to vaccine components. Use caution in pregnant or lactating bitches unless the label and your veterinarian advise otherwise. Delay vaccination during acute illness until the dog recovers.

Dosage and Usage

Follow the official product label and your veterinarian’s protocol. General, widely published guidance includes:

• Puppy series: begin as early as 6 weeks of age.
• Administer one dose every 3 to 4 weeks until at least 16 weeks of age.
• Adult dogs not previously vaccinated: typically receive an initial dose followed by a second dose in 3 to 4 weeks.
• Revaccination: administer boosters as recommended by the label and your veterinarian, often annually or at intervals your clinic supports.

Reconstitute the lyophilized vaccine with the supplied diluent just before use. Administer the full dose subcutaneously. Do not split doses. Do not mix with other products unless the label specifically allows it.

Strengths and Forms

Common presentations include single-dose vials of freeze-dried vaccine with a matching sterile diluent, often designed for a low-volume 0.5 mL final dose after reconstitution. Multi-count cartons and clinic packs may also be available. Availability can vary by lot and supplier.

Missed Dose and Timing

If a puppy or adult dog misses a scheduled dose in the series, contact the veterinarian for guidance. In general terms, the series is resumed rather than restarted unless the interval has been prolonged. Do not double doses. For annual or later boosters, being late may leave a gap in protection, so schedule as soon as practical.

Storage and Travel Basics

Store the vials and diluent refrigerated. Keep the product cold and protected from light. Do not freeze. Reconstitute immediately before administration and use the entire dose promptly. Discard any unused reconstituted vaccine according to local regulations. When transporting to a clinic, you should keep the vaccine in an insulated container with cold packs and avoid direct contact between vials and ice.

Cold-chain handling is maintained during US delivery from Canada. If a shipment arrives warm or with compromised packaging, contact support and your clinic before use.

Benefits

• Core protection against distemper, adenovirus type 2, parainfluenza, and parvovirus.
• Low-volume Edge dose designed for comfort during injection.
• Modified live components support a strong immune response.
• Convenient single-dose vials for precise clinic or shelter use.
• Canadian pricing with US shipping access for eligible orders.

Side Effects and Safety

• Mild soreness or swelling at the injection site.
• Transient fever, lethargy, or decreased appetite.
• Brief nasal discharge or cough may occur with respiratory antigens.
• Occasional gastrointestinal upset such as soft stool.

Serious reactions are uncommon but possible, including facial swelling, hives, vomiting, collapse, or anaphylaxis. Immune-mediated events may rarely occur. Modified live vaccines may pose risk in severely immunocompromised animals. Any unexpected or severe reaction requires immediate veterinary care. Report suspected adverse events to the veterinarian and the manufacturer as directed on the label.

Drug Interactions and Cautions

• Do not mix in the same syringe with other products unless the label allows.
• Immunosuppressive therapies, including high-dose corticosteroids or chemotherapy, can reduce vaccine response.
• Administering antibody-containing products (such as immune serum) too close to vaccination may interfere with immunity.
• Vaccinate only healthy animals; defer during illness or after recent surgery if advised by the veterinarian.

Use aseptic technique. Do not use the vaccine if the vial is cracked, the contents are discolored, or the cold chain has been compromised.

What to Expect Over Time

Puppies receive a series to cover the window when maternal antibodies wane. After the series and the first booster, many clinics follow annual or tailored schedules. Owners can expect brief, mild post-vaccination effects that resolve within a day or two. Protective immunity typically develops in the weeks following vaccination, but exposure risk, maternal antibodies, and overall health can affect response. Keep routine wellness visits so your veterinarian can adjust the plan as your dog ages.

Compare With Alternatives

Some clinics use a standard-volume formulation for the same antigens. A closely related option is Nobivac® Canine 1 DAPPv, which covers the same four core viruses. For very young puppies, clinicians may choose a targeted parvovirus and distemper product such as Nobivac® Puppy DPV during the early series. Your veterinarian may also add leptospirosis coverage based on local risk.

Pricing and Access

See current price and cost options online. You can compare Canadian pricing and complete checkout with US delivery from Canada. If your clinic requires direct-to-clinic shipping, enter the clinic address at checkout.

To explore other veterinary items by category, browse Pet Medications.

Availability and Substitutions

Stock can vary by lot. If this vaccine is temporarily unavailable, a veterinarian may recommend a comparable alternative to maintain core protection. Do not switch formulations mid-series without consulting your clinic, as protocols can differ. Some regions may require that vaccines ship to or be administered by a licensed veterinarian.

Patient Suitability and Cost Saving Tips

This product suits healthy dogs needing core viral protection, from initial puppy series through adult boosters. Dogs with a history of severe vaccine reactions or certain immune conditions may require special plans or pre-medication, guided by a veterinarian.

To manage costs, coordinate multi-pet vaccination visits, combine core and lifestyle vaccines during one appointment when appropriate, and align boosters with wellness exams. Ordering multiple items in a single shipment may reduce per-order fees. Some owners also schedule reminder alerts for booster due dates to avoid gaps in protection.

For region-based coverage, some clinics pair DAPPv with leptospirosis. Learn more about that option at Nobivac® Canine Lepto 4. For broader canine care topics, see articles like Droncit For Cats And Dogs and Hyperglycemia In Dogs.

Questions to Ask Your Clinician

• What puppy series schedule do you recommend for my dog’s age and risk?
• When should boosters be given after the initial series?
• Should we add leptospirosis or other lifestyle vaccines in our area?
• How do you manage dogs with prior vaccine reactions?
• Can this vaccine be given at the same visit as other products?
• What signs after vaccination require a recheck?
• If a dose is late, how should we resume the series?

Authoritative Sources

• Merck Animal Health – Dog Portfolio
• USDA Center for Veterinary Biologics
• Health Canada Drug Product Database

Ready to proceed? You can order with US delivery from Canada. This content is for informational purposes and does not replace veterinary advice.