Nobivac Canine Lepto 4® Vaccine for Dogs

Nobivac Canine Lepto 4 is a veterinary vaccine for dogs. It helps protect against leptospirosis caused by four common serovars. You can view pricing without insurance, with US delivery from Canada.

What Nobivac Canine Lepto 4 Is and How It Works

Nobivac Canine Lepto 4® is a four‑way leptospirosis vaccine for dogs. It contains antigens from Leptospira canicola, grippotyphosa, icterohaemorrhagiae, and pomona to help stimulate protective immunity. The treatment is used as part of a canine preventive care plan against a zoonotic bacterial disease.

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

This medicine is typically administered by a veterinarian or trained professional. It may be combined in scheduling with other canine core vaccines when appropriate. Discuss the timing and suitability with your veterinary team to align with local risk and clinic protocols.

Who It’s For

The lepto 4 dog vaccine is intended for healthy dogs at risk of exposure to Leptospira. Risk increases with outdoor activity, contact with wildlife or standing water, or residence in endemic regions. Puppies often begin vaccination when old enough per label and clinical guidance.

The Nobivac Leptospirosis 4-way vaccine is not for sick, febrile, or severely immunocompromised animals. Use caution in pregnant or lactating dogs unless a veterinarian determines that benefits outweigh risks. Dogs with a history of vaccine reactions may need a tailored plan.

To learn more about this infection and exposure risk, see our overview of Canine Leptospirosis.

Dosage and Usage

Per the product label, an initial series usually includes two doses administered 2 to 4 weeks apart. A single 1 mL dose is given by subcutaneous injection. After the primary series, dogs typically receive periodic revaccination on a schedule recommended by the label and your veterinarian.

Use aseptic technique. Reconstitute lyophilized components only with the provided sterile diluent when applicable, then gently mix. Administer promptly after mixing. Do not mix with other products unless the label specifically directs compatibility.

If your clinic also administers core puppy vaccines during the same visit, your team may coordinate timing with parvovirus and distemper products such as Puppy DPV. For adult dogs on broader protocols, practices may also schedule combination series similar to Canine EDGE DAPPv when indicated.

Strengths and Forms

This vaccine is supplied as single-dose or multidose presentations for clinic use. Labels commonly list a 1 mL dose volume per dog. Availability may include presentations packed with separate diluent for reconstitution.

Some practices prefer format options to streamline inventory. The Nobivac Lepto 4 10 dose can help support higher-throughput vaccination days, while single-dose vials may suit lower-volume settings. Branding is by Merck Animal Health; you may also see references to Merck Nobivac Lepto 4 in clinical materials.

Missed Dose and Timing

If the second dose in the initial series is delayed, consult your veterinarian for timing based on label guidance. Do not repeat doses more often than recommended. Future revaccination intervals should follow official directions and clinic standards.

Storage and Travel Basics

Store unopened vaccine under refrigeration as directed on the label. Protect vials from light. Do not freeze. Use only clear, properly mixed product and discard if the appearance is abnormal.

Reconstituted vaccine should be administered without delay. Keep out of reach of children and pets. When transporting vials to or from a clinic setting, use appropriate insulated carriers and verified cold packs to maintain label temperatures.

For households that also manage feline immunizations, see companion options like Feline BB and Feline 3 HCP for context on species-specific handling guidance.

Benefits

This medicine helps reduce the risk of leptospirosis illness in dogs. It supports protocols in regions where the bacteria are prevalent. The treatment can be scheduled alongside other preventive care under veterinary supervision.

Using an established vaccine series can help streamline clinic operations and owner reminders. Many clinics integrate this product into annual wellness plans depending on local epidemiology.

Side Effects and Safety

• Injection-site tenderness: mild soreness or swelling
• Transient lethargy: short-term tiredness
• Reduced appetite: usually brief
• Low-grade fever: may resolve without treatment

Serious but rare reactions can include hypersensitivity or anaphylaxis. Immediate veterinary care is required for facial swelling, hives, vomiting, collapse, or breathing difficulty. Report adverse events to your veterinarian and the manufacturer per label instructions. Dogs with a prior reaction history may need premedication strategies decided by the veterinarian.

Drug Interactions and Cautions

Immunosuppressive drugs, including certain corticosteroids or cytotoxic agents, may reduce vaccine response. Concurrent illness can blunt immunity and increase adverse event risk. Maternal antibodies in young puppies can interfere with serologic response, which is why timing follows label and clinical guidance.

Do not mix this vaccine in the same syringe with other products unless the label permits. Use only sterile needles and syringes. Always follow the official label and your veterinarian’s protocols.

What to Expect Over Time

After completing the primary series, your veterinarian may discuss ongoing revaccination. Protection is not immediate and depends on proper administration and scheduling. Exposure avoidance remains important even after vaccination.

Owners often receive reminders for periodic wellness visits. Keep records of vaccination dates and lot numbers. Bring documentation when boarding, traveling, or changing clinics so providers can verify status.

Compare With Alternatives

Clinics may coordinate leptospirosis protection alongside multivalent canine vaccines. Depending on age and history, your veterinarian may consider series such as Canine 1 DAPPv or advanced platforms like Canine EDGE DAPPv during routine visits. These products address different pathogens and scheduling needs; selection is based on clinic protocols and label guidance.

Pricing and Access

We list transparent options to help clinics and owners compare formats. You can review the Nobivac Lepto 4 price, check current availability, and evaluate the best fit for your practice or household. Canadian pricing with US shipping supports cross-border access for veterinary care items.

Want to explore current site-wide offers? Visit our Promotions page. Checkout is encrypted for your security. For broader browsing across species and conditions, see Infectious Disease and Pet Medications categories.

Availability and Substitutions

Stock status can vary by presentation. If a preferred pack size is unavailable, your veterinarian may recommend an alternative schedule or a similar class product appropriate for your dog’s risk profile. Listings may change without notice.

We offer Nobivac Lepto 4 for sale when inventory allows. If you do not see your desired format, check back or consult your clinic for suitable options consistent with label guidance.

Patient Suitability and Cost-Saving Tips

Good candidates typically include healthy dogs in regions with Leptospira exposure. Dogs with limited outdoor activity may still need protection if exposure risk exists. Puppies start on schedules once old enough per label.

Consider practical steps to manage costs and continuity. Clinics may prefer multidose packs for volume days, while single-dose vials can reduce wastage for small caseloads. Set annual reminders for revaccination. Keep copies of vaccine records when traveling or changing clinics.

Questions to Ask Your Clinician

• Series timing: when to start and how many doses
• Local risk: prevalence in your area or exposure settings
• Co-administration: giving with other canine vaccines
• Adverse reactions: what to watch for after a visit
• Recordkeeping: documents for boarding or travel
• Product choice: single-dose versus multidose vials

Authoritative Sources

For full, official directions and safety information, review the manufacturer’s materials and regulatory listings below.

• Merck Animal Health Nobivac canine portfolio overview
• Manufacturer product insert and indications
• USDA Center for Veterinary Biologics licensed products list

When planning vaccine protocols, your veterinarian may also discuss core series similar to Puppy DPV or broader adult combinations. If you manage mixed-species households, our feline listings such as Feline BB and Feline 3 HCP can provide context for cat-specific prevention.

Ready to proceed? You can place your request with CanadianInsulin for prompt, express, cold-chain shipping to your address when appropriate for this item.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.