Nobivac® Canine Lepto 4 Vaccine for Dogs

Nobivac Canine Lepto 4® is a veterinary vaccine that helps protect dogs against four common Leptospira serovars. CanadianInsulin ships from Canada to the US, pairing Canadian pricing with convenient US delivery. At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.

What Nobivac® Is and How It Works

Nobivac Canine Lepto 4® is an inactivated bacterin for dogs. It helps prevent leptospirosis caused by Leptospira canicola, icterohaemorrhagiae, pomona, and grippotyphosa. The vaccine stimulates the dog’s immune system to generate protective antibodies. These antibodies reduce disease, leptospiremia, and urinary shedding after exposure. Many clinics administer Lepto 4 as a standalone shot or alongside core canine vaccines. This product is supplied as a 1 mL dose for subcutaneous injection.

Leptospirosis is a bacterial disease spread by wildlife and contaminated water. Areas with standing water, rodents, or farm runoff carry higher risk. Vaccination lowers the chance of severe kidney and liver complications linked to infection. CanadianInsulin provides US delivery from Canada with prompt, secure handling.

Who Nobivac® Is For

This vaccine is indicated for healthy dogs at risk of leptospirosis exposure. It is commonly recommended for dogs that hike, swim, visit parks, or live in regions where wildlife is present. Dogs in urban settings can also be exposed through puddles or rodent-contaminated areas. Do not vaccinate sick, febrile, or severely immunocompromised animals. Use in pregnant or lactating dogs only if the expected benefits outweigh risks, as advised by a veterinarian.

Dosage and Usage

Standard dosing follows the manufacturer label:

• Primary series: 1 mL subcutaneous injection, given as two doses 2 to 4 weeks apart.
• Starting age: commonly 9 weeks of age or older, per label and veterinary guidance.
• Booster: administer one 1 mL booster annually to maintain protection.

Administer using aseptic technique. Shake the vial well before use. Do not mix with other products unless labeled for combination. Follow the official label and clinic protocol for timing and re-vaccination.

Strengths and Forms

Nobivac Canine Lepto 4 is typically supplied as single-dose vials containing a 1 mL dose for subcutaneous injection. Packaging sizes can vary by clinic inventory and distributor. Availability may differ by province and season.

Missed Dose and Timing

If the second dose in the primary series is delayed beyond 4 weeks, veterinary clinics often complete the series as soon as practical. If a substantial delay occurs, some clinicians restart the two-dose series to ensure adequate immunity. Annual boosters are recommended to maintain protection. Follow the product label and clinic guidance when schedules vary.

Storage and Travel Basics

Store unopened vials under refrigeration. Do not freeze. Protect from light. Transport with cold packs to maintain the cold chain. Once drawn into a sterile syringe, administer promptly and discard any unused portion. Keep out of reach of children and animals. When traveling to a clinic, carry the vial in your insulated bag and keep it cold.

Benefits

• Protects against four key Leptospira serovars linked to canine disease.
• Helps reduce disease severity, leptospiremia, and urinary shedding.
• 1 mL subcutaneous dosing simplifies clinic workflow.
• Can be scheduled alongside core canine vaccinations under veterinary guidance.
• Supports community health by lowering bacterial shedding in the environment.

Side Effects and Safety

• Common: temporary soreness at the injection site, mild swelling, low-grade fever, reduced appetite, or lethargy.
• Less common: transient vomiting or diarrhea.
• Rare: hypersensitivity or anaphylactic reactions requiring immediate veterinary care.

Serious reactions are uncommon but can occur with any vaccine. Observe dogs after vaccination and contact a veterinary clinic if worrisome signs develop. Dogs with a history of vaccine reactions may require pre-medication or modified schedules as directed by a veterinarian.

Drug Interactions and Cautions

Concomitant use of immunosuppressive drugs, such as corticosteroids or certain chemotherapies, may blunt the vaccine response. Avoid mixing in the same syringe with other products unless the label states compatibility. Administer to healthy dogs only. For antibiotic topics related to pet care, see educational articles like Cephalexin For Dogs and Baytril Antibiotic.

What to Expect Over Time

Protection develops after the primary two-dose series. Maximum benefit is expected about two weeks following the second dose. Annual boosters help sustain immunity, especially in regions with year-round exposure. Some dogs may experience mild, short-lived post-vaccination tiredness. Maintain regular preventive care and discuss regional risks with a veterinary professional.

Compare With Alternatives

Clinics may choose a standalone leptospirosis vaccine or a broader vaccination plan that pairs core antigens with leptospirosis. For core coverage against distemper and parvovirus, consider products like Nobivac® Canine 1 Dappv or age-appropriate starter options such as Nobivac® Puppy Dpv. Selection depends on age, exposure risk, and clinic protocols.

Pricing and Access

See current pricing online and compare the cost with Canadian pricing that ships to the US. Order with secure checkout and track your US delivery from Canada. If clinic protocols require dispensing, upload the prescription and we confirm it with the practice. Many pet owners find meaningful cash-pay savings versus typical local prices.

Availability and Substitutions

Inventory can vary by season and region. If this vaccine is temporarily unavailable, a prescriber may recommend an alternative leptospirosis vaccine or adjust the schedule with other approved canine vaccines. Browse additional Pet Medications if a substitution is needed for related care.

Patient Suitability and Cost Saving Tips

Good candidates include healthy dogs in areas where leptospirosis is present or dogs with outdoor exposure. Dogs with acute illness, high fever, or prior severe vaccine reactions may not be suitable without special precautions. Puppies should begin on a schedule appropriate for age and clinic guidance.

• Plan multi-pet appointments to streamline visits and reduce separate handling fees.
• Coordinate annual boosters with routine wellness exams and preventives.
• Consider long-acting preventives alongside vaccines when appropriate, such as heartworm options like Proheart 6.
• For seasonal allergies managed separately from vaccination, veterinary teams may use treatments like Apoquel under guidance.
• Cold-chain handling is maintained during transport to safeguard product integrity.

Questions to Ask Your Clinician

• Is leptospirosis a known risk in this area or for this dog’s lifestyle?
• What is the recommended starting age and booster timing for this clinic?
• Can this vaccine be given with core vaccinations at the same visit?
• How should potential vaccine reactions be monitored at home?
• What steps are taken if the booster window is missed?
• Are pre-medications needed due to prior vaccine sensitivity?

Authoritative Sources

• FDA DailyMed
• Health Canada DPD
• Manufacturer Information

Storage and Travel Basics

Keep vials refrigerated and avoid freezing. Use an insulated container with cold packs during transport. Store in your refrigerator on arrival. Do not shake excessively.

Missed Dose and Timing

If the second dose is delayed, complete the series promptly. When delays are significant, clinics may restart the primary series; follow label and clinic protocol.

Ready to save with Canadian pricing and US delivery from Canada? Order Nobivac Canine Lepto 4 with secure checkout and prompt shipping. This page provides general information and does not replace veterinary advice. Always follow the official label and clinic guidance.