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Soliqua® Solostar Pens for Type 2 Diabetes
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This combination pen pairs long-acting insulin glargine with lixisenatide for adults with type 2 diabetes. It helps improve fasting and after-meal glucose when diet and exercise are not enough. This page explains how to buy insulin glargine lixisenatide pen, compares options, and outlines access, including choices without insurance, with US shipping from Canada.
What Soliqua Is and How It Works
Soliqua® contains basal insulin glargine and the GLP-1 receptor agonist lixisenatide. The insulin component lowers fasting glucose by providing steady background coverage. The GLP-1 component helps control post-meal spikes by slowing gastric emptying and increasing glucose-dependent insulin release.
CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.
This medicine is taken once daily before the first meal. It is intended to be used with diet and exercise. Do not combine it with other GLP-1 receptor agonists or with mealtime insulin. It is not for type 1 diabetes or for treating diabetic ketoacidosis.
For a device overview, see Dual Action Support.
Who It’s For
The treatment is for adults with type 2 diabetes who need better control on basal insulin alone, a GLP-1 therapy alone, or oral agents. It may be appropriate when fasting and post-meal readings remain above target despite lifestyle measures.
Do not use it for type 1 diabetes. Avoid if you have a history of serious hypersensitivity to insulin glargine or lixisenatide. People with severe gastrointestinal disease, especially gastroparesis, should not use a GLP-1 agent. Your clinician will assess kidney function and overall risks.
Learn more about the condition at Type 2 Diabetes.
Dosage and Usage
Use this medicine once daily within the hour before your first meal. Inject subcutaneously into the abdomen, thigh, or upper arm. Rotate injection sites with each dose. Follow the dose your prescriber selects based on your prior basal insulin use and treatment history.
General label guidance includes starting at a low dose and adjusting stepwise to reach fasting glucose goals. Titration should be cautious to reduce hypoglycemia and gastrointestinal effects. Never share pens. Do not inject into a vein or muscle.
If your clinician transitions you from standalone basal insulin or a GLP-1 agent, the starting dose and schedule come from the official label. When unsure, consult that label and your prescriber rather than changing any dose yourself.
For device landscape and technique refreshers, see Diabetes Tech and browse Insulin Pens.
Strengths and Forms
The pen is a prefilled disposable device. Each pack typically contains five 3 mL pens. Many patients know this as the Soliqua Solostar 100/33 prefilled pen.
Availability can vary by pharmacy and by region. Packaging and device color may differ from images. Confirm the pen type on the carton before use.
Missed Dose and Timing
If you miss a dose, skip it and take your next dose at the usual time the following day. Do not take two doses on the same day. If you are uncertain, follow the official label and ask your healthcare professional.
Storage and Travel Basics
Before first use, store unopened pens in the refrigerator. Do not freeze. Keep away from light. After first use, most pens may be kept at room temperature for a limited time per the label. Discard the pen after the in-use period ends, even if insulin remains.
Keep the cap on when not in use. Do not store with a needle attached. Protect from heat during travel. Use a protective case and carry a backup pen when possible. Bring your prescription or a travel letter if crossing borders. A micro trust cue: encrypted checkout supports secure ordering.
Pen Handling and Sharps Disposal
Wash hands. Attach a new needle for each injection. Prime the pen as directed before the first dose of a new pen. Dial the selected dose. Insert the needle into the skin, press the button, and hold for several seconds to ensure full delivery. Remove the needle and dispose of it in an appropriate sharps container.
Rotate injection sites to reduce skin issues. Never share your pen or needles. Follow local rules for sharps disposal or use a mail-back program.
Benefits
This medicine simplifies therapy by combining basal insulin with a GLP-1 agent in one daily injection. It can reduce fasting and after-meal glucose with a single device. Many patients appreciate dose titration using one pen and reduced injection burden compared with separate products.
Side Effects and Safety
- Common: nausea, vomiting, diarrhea
- Injection site redness or itching
- Headache or dizziness
- Decreased appetite or a feeling of fullness
Hypoglycemia can occur, especially if meals are delayed, activity increases, or you use other glucose-lowering medicines. Severe allergic reactions are rare but possible. Pancreatitis has been reported with GLP-1 therapies; seek urgent care for severe, persistent abdominal pain. Kidney issues may worsen with dehydration from vomiting or diarrhea. Discuss risks with your prescriber.
Drug Interactions and Cautions
Using this treatment with sulfonylureas or other insulin may increase hypoglycemia risk. Lixisenatide can slow gastric emptying, which may affect the absorption of some oral medications. Your clinician may ask you to monitor certain drugs more closely. Thiazolidinediones with insulin can cause fluid retention; heart failure may be a concern in susceptible patients.
Alcohol, illness, stress, and changes in activity can alter glucose needs. Always consult the official label for the full interaction list.
What to Expect Over Time
Glucose patterns may improve as you titrate to your target fasting level. Gastrointestinal symptoms, if present, often appear early and may lessen as your body adjusts. Consistent dosing before the first meal, predictable meals, and regular activity support stable control.
Track fasting and post-meal readings according to your care plan. Bring logs to appointments so your clinician can adjust therapy. If your Soliqua Solostar cash price affects adherence, discuss financial options early.
Compare With Alternatives
Some adults may consider another fixed-ratio combination, such as Xultophy® Prefilled Pen. Others may use a long-acting insulin alone, such as Toujeo® Doublestar Prefilled Pen, with a separate mealtime plan if needed. Your prescriber can help select the class and device that fit your goals and prior history. Explore broader options in Long Acting Insulin.
Pricing and Access
We reflect Canadian pricing with transparent product listings. Many patients compare options by insurance status, copays, and pharmacy fees. If you need Soliqua Solostar US shipping, we coordinate secure fulfilment. We also support US delivery from Canada for eligible orders.
To reduce out-of-pocket exposure, check manufacturer assistance programs and ask about multi-pen fills. See current offers at Promotions. If you are researching generic insulin glargine lixisenatide pen price across therapies, note that fixed-ratio combinations are branded products.
Availability and Substitutions
Supply can vary by dose and pack size. If this product is unavailable, your prescriber may recommend a therapeutic alternative from the same or a different class. We will not substitute without your clinician’s guidance and a valid prescription.
For qualified orders, you can purchase Soliqua Solostar pens online after completing the required steps.
Patient Suitability and Cost-Saving Tips
Good candidates are adults with type 2 diabetes who need both basal coverage and post-meal support. It may not suit those with recurrent nausea, gastroparesis, or pancreatitis history. It is not recommended for type 1 diabetes or for diabetic ketoacidosis.
To manage costs, ask about multi-month supplies, refill reminders, and timing refills before travel. Compare coverage policies and preferred pharmacy networks. If affordability is a barrier, discuss community programs and samples with your healthcare professional. You can also review generic insulin glargine lixisenatide pen price discussions with your clinician to understand class options.
Questions to Ask Your Clinician
- Starting dose and how it was selected
- Titration steps and fasting glucose targets
- How to manage nausea or decreased appetite
- Signs of hypoglycemia and what to keep on hand
- Whether other diabetes drugs should be adjusted
- Travel and storage plans for upcoming trips
Authoritative Sources
DailyMed: Soliqua 100/33 Prescribing Information
Health Canada Drug Product Database
Pricing and Ordering
Ready to proceed? You can add to cart, upload your prescription, and complete checkout for Ships from Canada to US with express, cold-chain shipping. This content is for general information and does not replace the approved label or your clinician’s advice.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
How is this combination pen different from taking two separate injections?
It pairs basal insulin with a GLP-1 agent in one device. The insulin supports fasting control, while the GLP-1 component helps after meals. Using a single pen may simplify your routine and titration. Your prescriber may still adjust other medicines. Review your glucose logs regularly to ensure the chosen approach meets your targets safely.
When should I inject the dose each day?
Inject once daily within the hour before your first meal. Use the same general time window each day to keep dosing consistent. Rotate injection sites to reduce skin problems. Do not inject into irritated skin. Follow the official label and your prescriber’s instructions for any changes.
What if I feel nauseated after starting this therapy?
Mild nausea can occur, especially early on. Eat smaller meals, avoid large high-fat meals, and maintain hydration. If symptoms persist or worsen, contact your healthcare professional. Severe, persistent abdominal pain may signal pancreatitis and needs urgent evaluation. Your clinician can also consider slower titration if appropriate.
Can I use it with other diabetes medicines?
Your clinician may combine it with metformin or other oral agents. Do not use it with another GLP-1 therapy or with mealtime insulin. Using it alongside sulfonylureas or other insulin can raise hypoglycemia risk. Any medication changes should be directed by your prescriber after reviewing glucose trends and the label.
How long can an in-use pen be kept at room temperature?
Unopened pens should be refrigerated. After first use, most pens can be kept at room temperature for a limited period per the official label. Protect from heat and light. Do not freeze. Keep the cap on and remove the needle after each injection. Discard the pen once the in-use window ends, even if insulin remains.
Do I need a new needle for each injection?
Yes. Use a new needle every time to reduce infection risk and ensure accurate dosing. Priming steps are required for a new pen. Dispose of used needles in a sharps container. Never share pens or needles with anyone, even if the needle is changed.
What if my pharmacy cannot supply this product?
Supply varies. Your prescriber may recommend a therapeutic alternative from the same or a different class. We do not substitute without guidance. If you need access options, ask about multi-month fills, travel planning, and timing refills before trips. Your clinician can advise on a safe alternative if this item is not available.
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