Stelara® Prefilled Syringe for Plaque Psoriasis

Stelara® Prefilled Syringe is a prescription biologic used for immune-mediated conditions like plaque psoriasis. It ships from Canada to US with a valid prescription. This page outlines what the treatment does, how to use it safely, and ways to manage payment without insurance.

What Stelara Is and How It Works

At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.

This treatment contains ustekinumab, a monoclonal antibody that targets the p40 subunit shared by interleukins 12 and 23. By blocking these cytokines, the medicine may reduce inflammatory activity in skin, joints, and the gastrointestinal tract. It is approved for adults with plaque psoriasis and psoriatic arthritis, and for moderately to severely active Crohn’s disease and ulcerative colitis. Pediatric plaque psoriasis indications exist in some regions; prescribers follow local labeling.

Who It’s For

This therapy is for adults with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. It also treats active Psoriatic Arthritis, alone or with nonbiologic disease-modifying agents. For Crohn’s disease and ulcerative colitis, clinicians may use it after inadequate response, loss of response, or intolerance to conventional treatments or to tumor necrosis factor blockers. Some adolescents with plaque psoriasis may be eligible based on local labeling and prescriber judgment.

People with clinically significant infections, active tuberculosis, or a history of serious hypersensitivity to ustekinumab should not use this product. Screening for latent tuberculosis is generally recommended before starting therapy. Live vaccines are not advised during treatment.

Dosage and Usage

The prefilled syringe is designed for subcutaneous injection after a clinician demonstrates proper technique. For plaque psoriasis and psoriatic arthritis, injections occur at week 0 and week 4, then on a regular schedule every 12 weeks. The syringe size is chosen by the prescriber, often based on body weight for skin disease in adults. For Crohn’s disease and ulcerative colitis, treatment typically starts with a single intravenous infusion in a clinic, followed by the first subcutaneous dose 8 weeks later, then maintenance every 8 weeks.

Allow the syringe to reach room temperature out of the carton for a short period before injecting. Inspect the liquid; do not use if discolored or contains particles. Do not shake. Rotate injection sites on the thighs, abdomen, or upper arms, avoiding areas that are tender, bruised, scarred, or affected by psoriasis. Clean the skin and let it dry. Do not inject through clothing. If unsure about timing or technique, consult the official label or a healthcare professional. For background reading on biologic therapy principles, see Comprehensive Guide.

Strengths and Forms

The prefilled syringe is available in commonly used presentations for subcutaneous use, including 45 mg/0.5 mL and 90 mg/mL. Availability can vary by indication and supplier. Intravenous induction is supplied separately for clinic administration when used for inflammatory bowel disease.

Missed Dose and Timing

If a dose is missed, take it when remembered unless it is close to the next scheduled injection. Do not inject two doses at once. Resume the regular schedule. If the gap is long, ask the prescriber how to restart. Keep a calendar, phone reminder, or injection log to support adherence.

Storage and Travel Basics

Store the syringes in a refrigerator between 2°C and 8°C (36°F to 46°F). Keep them in the original carton to protect from light. Do not freeze or shake. The label allows a one-time room-temperature period; if needed, a clinician or the package insert can confirm the exact duration for the presentation supplied. Do not return a syringe to the refrigerator after it has been kept at room temperature.

For travel, pack the medicine in an insulated container with cool packs, separated so the syringe does not freeze. Keep it in carry-on luggage. Bring a copy of the prescription and supplies such as alcohol swabs and a sharps container or travel-safe alternative. Use a thermometer card if available. Never leave the product in a parked car. If temperature exposure is uncertain, contact the clinic or pharmacist for guidance.

Pen Handling and Sharps Disposal

This is a prefilled syringe, not a pen. Wash hands, gather supplies, and choose a clean, dry site. Remove the needle cover only when ready to inject. Pinch the skin to make a fold and insert the needle as shown by a clinician. Depress the plunger steadily until the syringe is empty, then withdraw and apply gentle pressure with gauze if needed. Do not rub the site.

Dispose of used syringes and needles immediately in an FDA-cleared sharps container. Do not throw loose needles into household trash or recycling. Follow local or state programs for sharps disposal. Keep all supplies out of reach of children and pets.

Benefits

• Infrequent maintenance dosing for skin and joint disease after initial doses.
• Self-injection option at home after training.
• Targets IL-12 and IL-23, key drivers of inflammation.
• Used across dermatology, rheumatology, and gastroenterology indications.
• Prefilled syringe format; no mixing or vial preparation at home.

Side Effects and Safety

• Upper respiratory infections, sore throat, or stuffy nose
• Headache or fatigue
• Injection-site redness, itch, or pain
• Stomach pain, nausea, or diarrhea
• Joint pain or back pain
• Itching or rash

Serious risks can include severe infections, reactivation of tuberculosis, allergic reactions including anaphylaxis or angioedema, rare posterior reversible encephalopathy syndrome, and possible increased risk of certain malignancies. Tell a healthcare professional promptly if signs of infection, persistent fever, shortness of breath, vision changes, or severe headache occur. Do not receive live vaccines during treatment and for a period after the last dose as advised by the prescriber.

Drug Interactions and Cautions

Live attenuated vaccines should be avoided. Non-live vaccines may be less effective during therapy. Concomitant use with other biologic immunomodulators can raise infection risk and is generally not recommended unless directed by a specialist. Tell the prescriber about past or current tuberculosis, chronic or recurrent infections, or any cancer history. People with helminth infections should be treated prior to starting therapy. Laboratory monitoring follows the clinician’s plan. For safety discussions related to immunotherapy, see Malignancy Risk.

What to Expect Over Time

Response patterns vary by condition. Many people need an initial period with scheduled doses before stable control is maintained. Skin, joint, and gastrointestinal symptoms may improve progressively with regular administration. The prescriber may adjust timing within label limits based on clinical response. Keep follow-up appointments, monitor for infections, and maintain injection records. If therapy is interrupted, a clinician will decide how to reinitiate. Consistent use and scheduling tools can help maintain continuity.

Compare With Alternatives

Other biologics treat similar conditions. Interleukin-23 inhibitors and interleukin-17 inhibitors are common alternatives. Two options available through this service include Skyrizi Cartridge and Cosentyx. Tumor necrosis factor blockers such as Humira are additional choices when appropriate. Discuss selection with the treating clinician, considering indication, prior therapy, comorbidities, and vaccination status.

Pricing and Access

Canadian pharmacy sourcing can lower cash-pay costs for specialty medicines. This service provides transparent pricing and secure checkout, with US shipping from Canada. Temperature-controlled packing is used when a refrigerated parcel is required. To explore savings, compare your out-of-pocket estimate with current pricing. For seasonal offers, see Promotions. Check eligibility rules set by your prescriber and local regulations before ordering.

Savings CTA: Review potential cash-pay savings based on strength and quantity. Pricing CTA: View today’s pricing and available presentations before submitting an order.

Availability and Substitutions

Supply can vary by strength and indication. If a specific syringe is unavailable, a prescriber may recommend an alternative therapy from the same class or another class. Clinic-administered induction for inflammatory bowel disease follows separate supply channels. No restock dates are promised.

Patient Suitability and Cost-Saving Tips

Good candidates can adhere to scheduled injections and monitoring. Those with uncontrolled infections, active tuberculosis, or prior severe hypersensitivity are not candidates. People planning live vaccinations should coordinate timing with their clinician. Multi-month fills may reduce per-shipment fees for refrigerated parcels. Set refill reminders and plan delivery ahead of travel. Combining clinic visits with injection windows can streamline lab checks and assessments. For broader condition context, see Plaque Psoriasis and Psoriatic Arthritis categories. For inflammatory bowel disease overviews, visit Crohns Disease.

Questions to Ask Your Clinician

• Is this therapy appropriate for my diagnosis and treatment goals?
• What baseline tests, such as tuberculosis screening, are needed?
• Can self-injection be done safely at home after training?
• How should vaccinations be scheduled during treatment?
• What signs of infection require urgent evaluation or testing?
• How will we monitor response and safety over time?
• What strategies help maintain an every-8- or every-12-week schedule?

Authoritative Sources

• Manufacturer Prescribing Information
• FDA DailyMed
• Health Canada DPD

Start your order: Order Stelara Prefilled Syringe online with prompt, express, cold-chain shipping and US delivery from Canada.

Disclaimer: Content is for general information only and does not replace medical advice. Use medicines only as directed by a licensed prescriber.