Trazodone Tablets for Depression

Trazodone is a serotonin modulator used for major depressive disorder. It may also reduce anxiety and nighttime awakenings when directed by your prescriber. You can buy trazodone online with US shipping from Canada, compare options, and learn how ordering works without insurance.

What Trazodone Is and How It Works

This medicine is an antidepressant classified as a serotonin antagonist and reuptake inhibitor. It blocks certain serotonin receptors and slows serotonin reuptake, which may help improve mood and sleep continuity. Effects can include sedation, so many patients take doses in the evening.

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This treatment is available as oral tablets. It is typically used as monotherapy for major depressive disorder, or as part of a broader care plan when clinically appropriate. For off-label uses, follow your prescriber’s guidance and local regulations.

If you are evaluating a trazodone purchase, review the safety sections below and discuss questions with your clinician.

Who It’s For

The tablet is indicated for adults diagnosed with major depressive disorder. It may be considered in patients who have not tolerated other antidepressants or who benefit from a sedating option at night. Some prescribers consider it for anxiety symptoms within a depressive episode.

Do not use it if you take monoamine oxidase inhibitors, within 14 days of stopping an MAOI, or are starting an MAOI. People with a recent heart attack, significant heart rhythm disorders, uncontrolled narrow-angle glaucoma, severe liver disease, or a history of priapism should discuss risks carefully. Visit our condition pages for related guidance on Depression and Anxiety.

Dosage and Usage

Follow the official label and your prescriber’s instructions. Tablets are usually taken after a meal or snack to reduce stomach upset. Evening dosing is common due to drowsiness. Starting doses may be lower and titrated up as tolerated.

Typical regimens divide doses during the day or concentrate dosing at bedtime when appropriate. Swallow tablets whole with water. Do not drive or operate machinery until you know how this medicine affects alertness. Do not stop suddenly; tapering may be needed to reduce discontinuation symptoms.

If you miss doses, adherence strategies can help. Use reminder apps, calendar alerts, or pharmacy packaging. If questions arise about timing or dose adjustments, consult your prescriber or pharmacist rather than self-changing your plan.

Strengths and Forms

Immediate-release tablets are commonly available in 50 mg, 100 mg, and 150 mg strengths. Some markets carry extended-release options; availability may vary by pharmacy. Your prescriber will select the strength and schedule suited to your plan.

Missed Dose and Timing

If you miss a dose, take it when remembered unless it is close to the next scheduled dose. If it is near the next dose, skip the missed dose and resume the regular schedule. Do not double up to catch up. For once-daily evening dosing, consider skipping if you are within a few hours of the next planned dose to avoid excessive sedation.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from light and moisture. Keep the medication in the original child-resistant container with the label intact. Keep out of reach of children and pets.

When you travel, pack your medication in carry-on baggage with your prescription label and a copy of your prescription. Use a small pill organizer for short trips if allowed by your local laws, but keep the labeled bottle for verification. If crossing borders, allow extra time for security checks and carry documentation that matches your legal name and dosing instructions.

Benefits

This medicine can help improve sleep continuity and reduce nighttime awakenings, which may support overall daytime functioning. It may also reduce anxiety symptoms that occur with depressive episodes. Some patients benefit from evening dosing that aligns with sedative properties.

If you are comparing options and availability, you can review trazodone for sale alongside other antidepressants and discuss choices with your prescriber. Consider tolerability, daytime sedation, and your work or driving schedule when evaluating fit.

Side Effects and Safety

• Drowsiness or fatigue: often strongest at treatment start
• Dizziness or lightheadedness: may worsen on standing
• Dry mouth and constipation: sip water and consider fiber
• Headache or nausea: often milder with food
• Blurred vision: avoid driving until symptoms resolve

Serious but less common risks include serotonin syndrome, suicidal thoughts or behavior in young adults, orthostatic hypotension, heart rhythm changes including QT prolongation, priapism, severe allergic reactions, and hyponatremia. Seek immediate help for symptoms of serotonin syndrome such as agitation, sweating, rapid heartbeat, muscle stiffness, or confusion. Report prolonged or painful erections promptly. Those with cardiac risk or on QT-prolonging drugs should discuss monitoring.

People living with diabetes or metabolic conditions may want to read about mental health context in our article on Diabetes and Mental Health; explore this with your clinician for individualized advice.

Drug Interactions and Cautions

Avoid MAOIs and linezolid due to serotonin syndrome risk. Use caution with other serotonergic agents such as SSRIs, SNRIs, triptans, tramadol, and St. John’s wort. Alcohol and other central nervous system depressants can increase sedation and impairment.

Strong CYP3A4 inhibitors (for example, ketoconazole, ritonavir) may raise levels; inducers (for example, carbamazepine, rifampin) may lower them. Use caution with drugs that prolong QT intervals, certain antiarrhythmics, macrolide antibiotics, or antipsychotics. If adjunctive antipsychotic therapy is being discussed, review background information such as Abilify Uses and speak with your prescriber.

What to Expect Over Time

Drowsiness may appear early and often eases with consistent bedtime routines. Mood improvements may take time and regular follow-up. Steady, daily use is important for assessing benefit. Keep a simple symptom journal to track sleep quality, energy, and mood across weeks.

If you notice persistent daytime sedation, dizziness on standing, or bothersome dry mouth, raise this at your next appointment. Do not stop abruptly; work with your prescriber on any changes. Consider aligning dose timing with your schedule to reduce conflicts with driving or safety-sensitive tasks.

Community awareness resources, such as our feature on World Mental Health Day, may help you plan questions for upcoming visits.

Compare With Alternatives

Selective serotonin reuptake inhibitors are first-line for many patients. If your clinician recommends an SSRI, you can compare options such as Fluoxetine and Zoloft. Tricyclics like amitriptyline may be considered when sedation is desired, though monitoring needs differ. Discuss class effects, side-effect profiles, and drug interactions to select a suitable plan.

Pricing and Access

Review formulary details, set quantity, and see the trazodone price during checkout. You can also compare tablet strengths and choose supply lengths that fit your schedule. For some strength options, you may see the trazodone 50 mg price presented next to other doses so you can evaluate per-tablet value. We provide encrypted checkout and clear order steps.

Orders are fulfilled at Canadian pricing and Ships from Canada to US. If you are looking for broader mental health options, browse our Mental Health category. For seasonal offers, see our Promotions page.

Availability and Substitutions

Supply can vary by strength and manufacturer. If a requested option is unavailable, your prescriber may recommend a therapeutically appropriate alternative. Some customers compare generics with brand references; if you intend to buy desyrel online, discuss brand needs with your clinician and confirm what your prescription specifies.

Patient Suitability and Cost-Saving Tips

Candidates include adults with major depressive disorder who can manage potential drowsiness. Those with significant cardiac disease, glaucoma risk, severe liver problems, or a history of priapism require extra caution. Avoid alcohol and be careful with other sedatives. Older adults may be more sensitive to orthostatic effects.

To save on costs, consider multi-month supplies if appropriate, synchronize refills, and use calendar reminders so you do not miss doses. Generic options typically offer value. If you compare choices across pharmacies, ensure dosing and manufacturer consistency unless your prescriber advises a change.

Questions to Ask Your Clinician

• Starting dose plan and timing
• How to manage daytime drowsiness
• Interactions with current medicines
• Warning signs to watch for
• When to schedule follow-up
• Plan for tapering if needed

Authoritative Sources

For complete prescribing details, see the FDA label on DailyMed; it provides dosing, risks, and interaction information: DailyMed official labeling index for trazodone hydrochloride tablets.

Health Canada’s Drug Product Database lists authorized products and status; review entries for Canadian information: Health Canada Drug Product Database search page.

For additional safety context, the FDA Medication Guides portal provides patient-focused summaries for many antidepressants: FDA Medication Guides overview for prescription medicines.

Medical disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice.

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