Please note: a valid prescription is required for all prescription medication.
Tresiba (insulin degludec) FlexTouch insulin pens
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Applies to all products originating from Canada. Maximum quantity limited to a 90-day supply per order.
Price range: $163.00 through $183.00
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Tresiba FlexTouch Pens are prefilled insulin pens that deliver insulin degludec, a long-acting (basal) insulin. They are used as background insulin to help manage blood glucose over a full day. This page summarizes practical basics for access and safe handling, including US shipping from Canada and options for people paying without insurance.
What Tresiba FlexTouch Pens Are and How They Work
Insulin degludec is a basal (background) insulin used to support steady glucose control between meals and overnight. After injection under the skin (subcutaneous), it forms a depot that releases insulin slowly. This helps cover baseline insulin needs and is not designed to correct sudden high glucose or replace mealtime insulin when that is also prescribed. Many people with diabetes use a basal insulin alongside nutrition planning, glucose monitoring, and other medicines.
Prescription details may be verified with the original prescriber when required.
On CanadianInsulin, requests are coordinated through a prescription referral process, and dispensing is completed by appropriately licensed pharmacies. For an overview of long-duration options that work similarly, browse the Long Acting Insulin category hub. For broader context on insulin types and use, the Tresiba Overview Article provides background and common terminology.
Who It’s For
This medicine is prescribed for diabetes mellitus when a clinician determines that basal insulin is appropriate. It may be used in type 1 diabetes (typically along with rapid-acting mealtime insulin) and type 2 diabetes (alone or with other glucose-lowering medicines). People who are comparing treatment pathways can review condition hubs such as Type 1 Diabetes and Type 2 Diabetes to see related therapies and supplies in one place.
It is not used for diabetic ketoacidosis (DKA), which requires urgent medical treatment. A key contraindication is a known serious hypersensitivity (allergic reaction) to insulin degludec or any component of the product. Clinicians may also reassess suitability during episodes of recurrent severe hypoglycemia or when insulin needs change substantially due to illness, steroid treatment, or major changes in intake and activity.
Dosage and Usage
Basal insulin dosing is individualized by the prescriber based on glucose data, other medications, and clinical factors. Many adults are instructed to take insulin degludec once daily, and some regimens allow flexibility in timing when needed, depending on the label and prescriber direction. Dose adjustments are usually made gradually, using home glucose results and the prescriber’s titration plan. When a person is switching from another basal insulin, clinicians often provide a structured transition plan and extra monitoring guidance.
For device technique and day-to-day routine, Tresiba FlexTouch Pens are used by attaching a new pen needle for each injection, priming per the instructions, then injecting into recommended sites such as the abdomen, thigh, or upper arm. Site rotation helps reduce lipohypertrophy (lumpy thickened skin) that can interfere with absorption. The pen should not be shared between people, even if a new needle is used, due to infection risk. For deeper reading, see Tresiba Dosage Guide and FlexTouch Pen Features.
- Same time daily: follow the prescribed schedule.
- Under-skin injection: do not inject into a vein.
- Do not mix: follow product instructions.
- Glucose checks: use the monitoring plan provided.
Strengths and Forms
This product is supplied as a prefilled pen device intended for multiple doses from a single pen. Insulin degludec pens are commonly available in 3 mL pen presentations, and cartons are often provided as a multi-pen pack. Strength availability can vary by market and dispensing pharmacy, so the exact presentation and labeling should be confirmed during the prescription review.
Tresiba FlexTouch Pens may be available in two concentrations, which affects dose dialing and maximum deliverable dose per injection. Patients should confirm that the concentration on the label matches the prescription and education provided. For related options and insulin formats, the Insulin Medications browseable hub can help organize comparisons.
| Presentation | Concentration | Notes |
|---|---|---|
| Prefilled pen | 100 units/mL | Often referred to as U-100 |
| Prefilled pen | 200 units/mL | Often referred to as U-200 |
| Pen volume | 3 mL | Check carton for exact contents |
Storage and Travel Basics
Unopened insulin pens are generally stored in the refrigerator until first use, then kept either refrigerated or at room temperature depending on the product instructions. Freezing can damage insulin, so pens should be protected from ice packs that directly contact the device. Heat and direct sunlight can also reduce potency. The in-use time (how long a pen can be kept after first use) is product-specific and should be taken from the package insert or pharmacy labeling.
Licensed Canadian partner pharmacies dispense medications for approved requests.
When traveling, carrying insulin in a temperature-stable pouch and keeping supplies in carry-on baggage can reduce risk from cargo hold temperature extremes. It also helps to bring extra pen needles, glucose testing supplies, and a backup plan for missed doses. Keep the pen cap on when not in use, and inspect insulin for changes in appearance as described in the instructions.
Quick tip: Keep a photo of the carton label and prescription in the travel bag.
Side Effects and Safety
All insulin products can cause hypoglycemia (low blood sugar), which is the most common clinically important risk. Symptoms may include sweating, shaking, confusion, headache, irritability, and fast heartbeat, and severe hypoglycemia can lead to seizures or loss of consciousness. People at higher risk include those with reduced food intake, unplanned strenuous activity, dose errors, or interacting medicines. A prescriber may recommend more frequent checks during illness, after a regimen change, or when switching insulins.
Other effects can include injection-site reactions (redness, pain, swelling), itching, and lipodystrophy (changes in fat tissue at the injection site). Weight gain and edema (fluid retention) can occur with insulin therapy. Serious allergic reactions are uncommon but require urgent medical care if symptoms such as widespread rash, swelling of the face or throat, or trouble breathing occur. For practical context on symptoms and follow-up questions, Tresiba FlexTouch Pens are discussed in the Tresiba Side Effects Guide.
- Most important risk: low blood glucose.
- Local reactions: redness or swelling.
- Skin changes: rotate injection sites.
- Urgent signs: severe allergy symptoms.
Drug Interactions and Cautions
Many drugs can change insulin requirements by increasing or decreasing blood glucose. Examples include corticosteroids, some diuretics, thyroid products, and sympathomimetics, which may raise glucose, and some antidepressants or ACE inhibitors, which may lower glucose in certain people. Alcohol can also increase hypoglycemia risk, especially when intake is inconsistent. Beta-blockers may mask some warning symptoms of low blood sugar, such as tremor or palpitations.
Some people use insulin with other glucose-lowering therapies, and combination plans may require closer monitoring when a medication is started, stopped, or changed. Thiazolidinediones (TZDs) used with insulin have been associated with fluid retention and possible worsening of heart failure in susceptible patients, so clinicians may monitor for swelling and shortness of breath. Any new symptoms, repeated lows, or unexplained highs should be reviewed with the prescribing clinician to confirm technique, timing, and medication compatibility.
Compare With Alternatives
Basal insulin choices differ in duration, concentration options, and how tightly timing needs to be followed. Alternatives commonly considered include insulin glargine (long-acting), insulin detemir (long-acting), and NPH insulin (intermediate-acting). A clinician may select an option based on glucose patterns, hypoglycemia history, kidney or liver function, and practical factors such as injection volume and device preference.
When comparing options, it can help to separate the insulin molecule from the device. For example, insulin glargine is available in pen formats like Lantus SoloStar Pens, while insulin detemir may be supplied in cartridge systems such as Levemir PenFill Cartridges. Tresiba FlexTouch Pens are one basal option within this group, and any switch should be guided by the prescriber with a clear monitoring plan.
- Insulin glargine: long-acting basal insulin.
- Insulin detemir: long-acting basal insulin.
- NPH insulin: intermediate-acting option.
Pricing and Access
Total out-of-pocket cost can vary by strength, quantity, and dispensing pharmacy, and some people compare options when using a cash-pay approach. CanadianInsulin facilitates cross-border access by coordinating prescription documentation and routing eligible requests to dispensing partners. Ships from Canada to US may be available for eligible prescriptions, subject to location and documentation requirements. A list of related diabetes medication categories is available through the Diabetes Medications hub and the broader Diabetes Category list.
Cash-pay access is available when insurance coverage is not used.
Before starting, confirm the prescribed concentration (U-100 vs U-200), the number of pens, and the supplies needed for safe use (pen needles, sharps container, and a monitoring method). Tresiba FlexTouch Pens require a valid prescription, and some prescriptions may need clarification during review. For non-time-limited site information that may affect costs, see Promotions.
Why it matters: Concentration mismatches can lead to dosing errors.
Authoritative Sources
For the most accurate safety and dosing instructions, consult official labeling and reputable references. These sources support clinician discussions and help confirm handling requirements, contraindications, and interaction cautions.
- FDA product overview and labeling access: Drugs@FDA Tresiba Application Overview
- NIH consumer drug information: MedlinePlus Insulin Degludec
For site actions, create an account, submit prescription details, and select prompt, express, cold-chain shipping at checkout.
This content is for informational purposes only and is not a substitute for professional medical advice.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
How often are Tresiba FlexTouch Pens taken?
This basal insulin is typically injected once daily at the same time. If needed, timing can vary according to the official label as long as adequate spacing is maintained. Follow your prescriber’s plan.
Can Tresiba FlexTouch Pens be mixed with other insulin?
Do not mix insulin degludec with other insulin products in the same syringe or pen. If you use mealtime insulin, inject it separately as directed.
What should I do if I miss a dose?
Take the missed dose when remembered, then resume the regular schedule. Ensure sufficient time between doses and do not double up. Consult the label or your clinician for guidance.
Where should I inject Tresiba FlexTouch Pens?
Inject subcutaneously in the abdomen, thigh, or upper arm. Rotate sites to reduce the risk of skin changes such as lipodystrophy.
How should I store the pens?
Unopened pens should be refrigerated as labeled and never frozen. In-use pens can be kept at room temperature for the labeled period. Protect from heat and light.
Are pen needles included with Tresiba FlexTouch Pens?
Pen needles are usually dispensed separately. Use a new needle for each injection and follow the pen’s Instructions for Use.
Can I travel with Tresiba FlexTouch Pens?
Yes. Keep insulin in carry-on luggage to avoid temperature extremes, bring your prescription, and use a travel case. Follow label storage directions during trips.
What is insulin degludec?
Insulin degludec is a long-acting basal (background) insulin. It is designed to provide steady insulin activity between meals and overnight rather than covering the sharp glucose rise after eating. Because it is long-acting, it is usually prescribed on a once-daily schedule, but the exact timing and dose are individualized. It is not used to treat diabetic ketoacidosis and is not a substitute for rapid-acting mealtime insulin when that is also prescribed. Official labeling and clinician instructions should guide use.
What is the difference between U-100 and U-200 insulin pens?
U-100 means the insulin contains 100 units per mL, while U-200 contains 200 units per mL. The medication is the same insulin (insulin degludec), but the concentration affects how much volume delivers a given number of units. Using the correct pen concentration matters for avoiding dosing errors and ensuring the prescription matches the product label. People should rely on the carton and pen labeling to confirm strength and follow the training provided by a healthcare professional for that specific device.
Can this basal insulin be used in type 1 and type 2 diabetes?
Basal insulin therapy can be prescribed in both type 1 diabetes and type 2 diabetes when clinically appropriate. In type 1 diabetes, a basal insulin is typically used together with rapid-acting insulin for meals and corrections. In type 2 diabetes, a basal insulin may be used alone or alongside other glucose-lowering medicines. Eligibility, regimen design, and monitoring intensity depend on individual factors such as glucose patterns, other medications, and risk of hypoglycemia, so a prescriber should confirm the right approach.
How do I monitor for low blood sugar while using long-acting insulin?
Monitoring for hypoglycemia usually involves a combination of glucose checks (fingerstick or continuous glucose monitoring, if used) and awareness of symptoms such as sweating, shakiness, confusion, or sudden fatigue. Risk can increase during illness, reduced food intake, unplanned activity, or medication changes. A prescriber may recommend extra checks after switching insulins or adjusting doses. Severe symptoms such as loss of consciousness, seizure, or inability to take carbohydrates require urgent medical care.
How should prefilled insulin pens be stored and carried when traveling?
Unopened insulin pens are commonly stored refrigerated, while in-use pens may be stored refrigerated or at room temperature depending on the product instructions. Insulin should not be frozen and should be protected from heat and direct sunlight. During travel, carrying insulin in a temperature-stable bag and keeping it in carry-on luggage can reduce exposure to temperature extremes. The allowable in-use time after first use varies by product and should be confirmed on the package insert or pharmacy labeling.
What should I ask my clinician before starting or switching basal insulin?
Key questions include which concentration is prescribed (U-100 vs U-200), what the target glucose checks should be during the transition, and how to handle missed or late doses based on the official label and the clinician’s plan. It is also reasonable to ask about injection technique, site rotation, and whether other medicines (such as steroids, diuretics, or beta-blockers) could change insulin needs or mask hypoglycemia symptoms. People using multiple insulins should confirm how basal and mealtime doses fit together.
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