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Verapamil SR (Verapamil HCl SR)
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Verapamil SR is an extended-release form of verapamil used in cardiovascular care. It is prescribed for selected blood pressure, chest pain, and rhythm-related needs. This page explains what the medication does, how it is commonly used, and what safety details are most important to review.
People may also look for cash-pay access options when they are without insurance. The sections below focus on practical basics such as strengths, handling, and interaction risks.
What Verapamil SR Is and How It Works
On this site, prescriptions can be coordinated with US delivery from Canada when documentation is complete. This medication belongs to the calcium channel blocker class, which affects how calcium moves into heart and blood vessel cells. By reducing calcium entry, the therapy can relax arterial muscle and lower the workload on the heart.
Sustained-release products are designed to release medicine gradually over time. That slower release can help provide steadier blood-pressure control across the day, depending on the specific formulation. CanadianInsulin operates as a prescription referral platform for eligible medications.
Verapamil also acts on the heart’s electrical conduction system, especially the atrioventricular (AV) node (the electrical relay between chambers). Because of that, it may slow heart rate and reduce certain rapid rhythms, but the appropriateness depends on the diagnosis and the product’s release profile.
Who It’s For
Verapamil sustained-release is commonly used for high blood pressure and chronic stable angina (chest pain from reduced blood flow). Condition hubs on this site can help with general context, including High Blood Pressure and Angina. Some clinicians also use verapamil to help control heart rate in certain supraventricular arrhythmias (fast rhythms that start in the upper chambers), with the exact formulation selected by the prescriber.
This medicine is not appropriate for everyone. It is generally avoided in people with certain conduction problems (for example, second- or third-degree AV block without a pacemaker), very low blood pressure, or cardiogenic shock. Caution is also used with some forms of heart failure and in significant liver impairment, because drug levels can rise. For rhythm-related conditions such as Atrial Fibrillation, diagnosis details matter, and the prescribing clinician should confirm whether verapamil is suitable.
Dosage and Usage
Extended-release verapamil products are usually taken once daily, though some formulations are taken in divided doses. The label may specify whether to take it with food and whether morning or evening timing is preferred. For Verapamil SR, tablets or capsules should typically be swallowed whole, because crushing or chewing can change the release pattern and increase side effects.
Missed-dose instructions vary by product and schedule, so the safest approach is to follow the dispensing label and prescriber directions. Doubling the next dose is generally not recommended unless a clinician specifically instructs it. Some people search for verapamil er to sr conversion when switching between products; that kind of change should be reviewed by a prescriber because “ER” and “SR” are not always interchangeable across manufacturers.
Quick tip: Keep an updated medication list for each prescription verification request.
Prescriptions are verified with your prescriber when required.
Strengths and Forms
Verapamil sustained-release is manufactured in multiple strengths and dosage forms. Depending on the manufacturer, it may be supplied as tablets or as capsules designed for extended release. Examples of naming you may see include Verapamil HCl SR on the label, as well as branded presentations such as Securon SR tablets or Veracaps SR capsules.
Common strengths include verapamil 120 mg sr, verapamil 180 mg sr, verapamil 240 mg sr, and verapamil sr 360 mg, though availability can vary by country and supplier. Verapamil SR may appear as a verapamil sr 120 mg capsule, a verapamil sr 180 mg capsule, or as tablets such as Vertab SR 240, depending on the product line.
| Strength | Possible form | Notes |
|---|---|---|
| 120 mg | Capsule or tablet | Extended-release; do not crush |
| 180 mg | Capsule or tablet | Extended-release; label timing varies |
| 240 mg | Capsule or tablet | Some products are labeled SR/ER |
| 360 mg | Capsule | Not all suppliers stock every strength |
Because different manufacturers may use different release technologies, the same milligram strength is not always a simple one-to-one switch. The dispensing label and prescriber instructions should be treated as the primary reference.
Storage and Travel Basics
Verapamil sustained-release is usually stored at controlled room temperature and protected from excess heat and moisture. Keep the medication in its original, labeled container, and avoid storing it in high-humidity areas such as bathrooms. If a desiccant packet is included in the bottle, it is typically meant to remain inside to help limit moisture exposure.
For travel, carrying doses in hand luggage can reduce exposure to temperature extremes and prevent missed doses if checked baggage is delayed. Keep a copy of the prescription or the pharmacy label with the medication container, especially for air travel. If capsules or tablets change in appearance after a refill, confirm the product name and strength on the label before taking the next dose.
Dispensing is handled by licensed Canadian pharmacies after documentation review.
Side Effects and Safety
Like other calcium channel blockers, verapamil can cause side effects related to blood-vessel relaxation and its effects on the heart’s conduction system. Constipation is a common complaint with this medicine. Other effects can include dizziness, headache, flushing, nausea, fatigue, and ankle swelling. In some people, Verapamil SR can lower heart rate or blood pressure more than intended, especially when combined with other cardiovascular therapies.
Why it matters: A slow heart rate can be subtle until dizziness or fainting occurs.
Seek urgent evaluation for symptoms that may signal a serious reaction, such as chest pain that is new or worsening, severe lightheadedness or fainting, marked shortness of breath, swelling with rapid weight gain, or signs of an allergic reaction (hives, facial swelling, trouble breathing). Clinicians may monitor blood pressure and pulse, and sometimes perform an ECG, particularly after starting therapy or changing a dose form.
Drug Interactions and Cautions
Verapamil has clinically important interactions because it can affect heart rate and because it is metabolized through pathways that other drugs can inhibit or induce. Combining it with beta blockers or certain antiarrhythmics may increase the risk of bradycardia (slow heart rate) or conduction block. Digoxin levels can rise with verapamil, so monitoring plans may change when both are used.
Some cholesterol medicines (notably certain statins), macrolide antibiotics, azole antifungals, and HIV therapies can increase verapamil exposure. Grapefruit products may also raise blood levels in some people. When anticoagulation is part of atrial fibrillation care, medication lists can become complex; the resource Warfarin For Clot Prevention provides general background to discuss with a clinician.
- Heart-rate lowering drugs: additive effects
- CYP3A4 inhibitors: higher verapamil levels
- Digoxin: possible level increase
- Alcohol: may worsen dizziness
Before dispensing, provide the pharmacy with a complete list of prescriptions, OTC products, and supplements. This is especially important if there is a history of conduction disease, heart failure symptoms, or significant liver disease.
Compare With Alternatives
Several medication classes are used for blood pressure and angina, and the best fit depends on the condition being treated and the person’s comorbidities. Other calcium channel blockers include non-dihydropyridines such as Diltiazem, which can also slow heart rate, and dihydropyridines such as Nifedipine XR, which tend to act more on blood vessels than on conduction.
Outside the calcium channel blocker class, prescribers may consider beta blockers, ACE inhibitors, or ARBs based on the clinical goal and tolerability. Verapamil SR is typically considered when rate control, angina symptom control, or blood-pressure lowering is needed and when contraindications are not present. For broader context on commonly used heart and vascular therapies, browse the Cardiovascular Category or the Cardiovascular Articles collection.
Pricing and Access
Out-of-pocket medication costs can vary by strength, dosage form, manufacturer, and quantity supplied. People searching for verapamil sr cost or verapamil sr cash price often find that extended-release products differ from immediate-release versions. If access is being arranged on a cash-pay basis, a valid prescription is still required and must match the requested strength and form.
For cross-border coordination, US shipping from Canada is available through partner pharmacies once the prescription is confirmed and the order is approved. Some users also check Available Promotions to understand site-wide programs that may apply. Verapamil SR access is coordinated after the prescription details align with the dispensed product.
Authoritative Sources
For the most reliable details on indications, contraindications, and interaction management, consult the product monograph or prescribing information supplied with the dispensed medicine. Independent references can also help clarify class effects, expected side effects, and when monitoring is commonly used in clinical practice.
These sources provide neutral, label-aligned information:
- MedlinePlus verapamil medicine overview and precautions
- DailyMed listings for verapamil extended-release products
- FDA Drugs@FDA database for labeling searches
To start a prescription request through your account, select prompt, express, cold-chain shipping at checkout if offered.
This content is for informational purposes only and is not a substitute for professional medical advice.
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What is Verapamil SR used for?
It is used for hypertension, chronic stable or vasospastic angina, and for ventricular rate control in certain supraventricular arrhythmias, per labeling.
How should I take sustained-release verapamil?
Take exactly as prescribed. Swallow sustained-release tablets or capsules whole. Take at the same time each day. Follow any food instructions on your label.
Can I switch from ER capsules to SR tablets?
Switching between extended-release forms should only be done by a clinician, because release profiles differ. Do not change formulations without guidance.
What are common side effects?
Constipation, dizziness, and headache are common. Edema, nausea, or fatigue can occur. Rarely, significant bradycardia, AV block, or worsening heart failure may occur.
Are there important drug interactions?
Yes. Strong CYP3A4 inhibitors or grapefruit can raise levels. Combining with beta-blockers or digoxin needs caution and monitoring. Review all medicines with your clinician.
What if I miss a dose?
Take it when remembered unless it is close to the next dose. Do not double up. Resume your normal schedule at the next dose time.
How should I store it?
Store at room temperature, dry, and away from heat and light. Keep in the original container and out of reach of children and pets.
What conditions is sustained-release verapamil used for?
Sustained-release verapamil is commonly prescribed to treat high blood pressure and chronic stable angina (chest pain related to reduced blood flow to the heart). Verapamil, as a drug, is also used in some settings to help control heart rate in certain supraventricular arrhythmias, but the specific formulation (immediate-release vs sustained-release) matters. The best indication for a given product depends on the prescribing information and the clinician’s assessment of cardiac history, other medications, and risk of conduction problems.
How is sustained-release verapamil different from immediate-release?
Immediate-release verapamil delivers medication more quickly and is taken multiple times per day in many regimens. Sustained-release (SR) products are designed to release the drug gradually, often allowing once-daily dosing and steadier blood levels. Because SR products can use different release technologies, switching between IR, ER, and SR versions is not always a simple milligram-for-milligram change. Any verapamil ER to SR conversion should be reviewed by the prescriber and matched to the correct dosage form on the prescription label.
Can verapamil lower heart rate or blood pressure too much?
Yes. Verapamil can slow heart rate and reduce blood pressure, which is part of how it works. In some people, especially those with underlying conduction disease, dehydration, or other heart-rate lowering medications, the effect can be excessive. Symptoms may include dizziness, fainting, unusual fatigue, shortness of breath, or chest discomfort. Clinicians may recommend checking pulse and blood pressure during initiation or after changes, and sometimes an ECG is used to assess conduction effects. Seek urgent care for severe symptoms.
What drug interactions are most important with verapamil SR?
Important interactions include other agents that slow heart rate or affect conduction (for example, beta blockers, certain antiarrhythmics, and digoxin). Verapamil is also affected by drugs that change CYP3A4 metabolism, including some macrolide antibiotics and azole antifungals, which may increase verapamil levels and side effects. Grapefruit products can increase exposure for some people. Because interaction risk depends on the full regimen, provide a complete medication and supplement list to the dispensing pharmacy and prescriber.
What should I ask my clinician before switching strengths or brands?
Ask whether the new product is the same release type (SR/ER vs immediate-release) and whether the tablet or capsule formulation changes how the dose is absorbed. Confirm the intended dosing schedule, whether it should be taken with food, and whether the product must be swallowed whole. It is also reasonable to ask what monitoring is appropriate after the change, especially if there is a history of slow heart rate, low blood pressure, or heart failure symptoms. Bring the exact label name (e.g., Verapamil HCl SR 120 mg) to the discussion.
How should extended-release verapamil be stored and handled while traveling?
Extended-release verapamil is generally kept at room temperature in a tightly closed, labeled container, protected from heat and moisture. Avoid storing it in bathrooms or leaving it in a hot car. When traveling, carry the medication in hand luggage to reduce temperature swings and to prevent missed doses if checked bags are delayed. Keep the pharmacy label or a copy of the prescription with the container for identification. If tablets or capsules look different after a refill, verify the name and strength on the label before use.
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