Verapamil SR for High Blood Pressure

What Verapamil SR Is and How It Works

Verapamil SR is an extended-release form of verapamil used to treat high blood pressure. This page helps compare strengths, check Verapamil SR price and cost online, and order from Canada with US delivery from Canada. It also supports cash-pay ordering without insurance at transparent Canadian pricing.

CanadianInsulin is a prescription referral service. We verify your prescription with your clinic, and licensed Canadian pharmacies dispense your order.

Verapamil belongs to the non-dihydropyridine calcium channel blocker class. It blocks L-type calcium channels in vascular smooth muscle and the heart. This relaxes blood vessels and slows conduction through the AV node. The result is lower blood pressure and reduced cardiac workload. The sustained-release design delivers medicine gradually over the day, helping maintain steadier levels and convenient once-daily dosing on many labels.

Depending on the specific labeled product, extended-release verapamil may also be used to help manage chronic stable angina. Always follow the indication and directions for the prescribed formulation.

Who Verapamil SR Is For

Most extended-release verapamil products are indicated for adults with essential hypertension. The goal is to reduce blood pressure as part of a long-term cardiovascular risk reduction plan.

Verapamil should generally be avoided in patients with known hypersensitivity to verapamil; severe hypotension; cardiogenic shock; second- or third-degree AV block or sick sinus syndrome unless a functioning pacemaker is present; and in severe left ventricular dysfunction or decompensated heart failure. Use caution in patients with conduction disturbances, bradycardia, hepatic impairment, or those taking other rate-slowing drugs. Safety in pregnancy and during breastfeeding should be evaluated with the prescriber.

Dosage and Usage

Follow the product-specific label and clinician instructions. A typical approach for sustained-release verapamil in hypertension is once-daily dosing. Many labels start at 120 mg or 180 mg once daily. Titration often occurs at weekly or biweekly intervals based on blood pressure response and tolerability. For many SR products, the maximum recommended total daily dose is 480 mg. Some labeled products allow the total daily dose to be given in divided administrations if needed.

Swallow tablets or capsules whole. Do not crush or chew extended-release forms. Take at the same time each day. Some products can be taken with or without food; follow the specific label to ensure consistent absorption.

Strengths and Forms

Verapamil sustained-release is available in several strengths and presentations. Availability can vary by manufacturer and pharmacy.

• Common strengths: verapamil SR 120 mg, verapamil SR 180 mg, verapamil SR 240 mg, verapamil SR 360 mg
• Presentations: sustained-release tablets and sustained-release capsules (often listed as verapamil HCl SR)
• Product labeling may describe 24-hour once-daily release. Some SR products are designed for morning or evening use as directed.

Examples of listing terms patients may see include “verapamil SR 120 mg capsule,” “verapamil SR 240 mg tablets,” or “verapamil HCl SR 180 mg.”

Missed Dose and Timing

If a dose is missed, take it when remembered unless it is close to the next scheduled dose. If it is near the time for the next dose, skip the missed dose. Do not take two doses at the same time to make up for a missed dose. Keep a consistent daily schedule.

Storage and Travel Basics

Store verapamil SR at room temperature, typically 20°C to 25°C (68°F to 77°F). Protect from excessive heat, moisture, and light. Keep tablets or capsules in the original container with the label.

When traveling, carry enough supply in original packaging within a hand luggage. Bring a copy of the prescription. If airport screening is required, medications can go through X-ray screening. For long trips, plan refills in advance so your order arrives before departure.

Benefits

Verapamil SR helps lower blood pressure as part of a long-term treatment plan. Lowering high blood pressure reduces the risk of strokes, heart attacks, and other cardiovascular problems. The sustained-release design supports steady control over a 24-hour period in many products and may improve adherence with once-daily dosing. SR tablets and capsules allow flexible strength selection, including verapamil SR 120 mg, 180 mg, 240 mg, and 360 mg, to match individual treatment plans set by a clinician.

Side Effects and Safety

• Constipation
• Dizziness or lightheadedness
• Headache
• Nausea
• Fatigue
• Edema, especially in the ankles
• Flushing

Serious or less common risks can include low blood pressure, slow heart rate, conduction blocks, worsening heart failure, or liver enzyme elevations. Seek medical attention for severe dizziness, fainting, shortness of breath, swelling, or a markedly slow pulse. The risk of bradycardia and AV block is higher when combined with other rate-slowing drugs such as certain beta blockers.

Drug Interactions and Cautions

Verapamil is metabolized primarily via CYP3A4. Potent inhibitors (for example, certain macrolide antibiotics or azole antifungals) can raise verapamil levels. Strong inducers such as rifampin and St. John’s wort may reduce effectiveness. Grapefruit or grapefruit juice can affect metabolism of some verapamil products. Avoid combining with other medicines that slow heart rate or depress AV conduction unless a clinician directs and monitors therapy.

Examples of rate-slowing medicines include beta blockers such as Metoprolol Sr, Propranolol, and Atenolol. Verapamil can increase digoxin levels. Certain statins, such as simvastatin, may require special consideration due to interaction potential; for background on cholesterol therapy, see Lipitor Uses. Alcohol may enhance the blood pressure–lowering effect.

Do not change doses or start new medicines without clinical guidance. Provide a full medication list, including over-the-counter drugs and supplements, to the prescriber and pharmacist.

What to Expect Over Time

Blood pressure generally begins to improve after initiation and dose titration. Some patients need several adjustments to reach a stable maintenance dose. Constipation and mild dizziness often lessen after the first weeks. Treatment is typically long term. Do not stop verapamil suddenly unless a clinician advises discontinuation and supervises the plan.

Compare With Alternatives

Other calcium channel blockers may be considered when selecting therapy. Non-dihydropyridine diltiazem offers a similar class effect with different tolerability for some patients. See once-daily options such as Diltiazem Hcl Cd. A dihydropyridine like Nifedipine Xr can also lower blood pressure and is often chosen when heart rate slowing is not desired. Beta blockers such as extended-release metoprolol may be considered for other cardiovascular indications when appropriate.

Pricing and Access

CanadianInsulin lists verapamil SR with Canadian pricing and US shipping. Check current Verapamil SR cost and compare sizes before checkout. This service ships from Canada to the US with prompt, express shipping. Many customers review the Verapamil SR price online to plan out-of-pocket budgets. Orders can be placed from Canada with US delivery from Canada. This can help those paying a cash price, including those purchasing without insurance after a clinician prescribes therapy. For broader options, explore Hypertension Cardiovascular products.

Strength, form, and pack size affect the final cost. Larger fills may lower per-tablet cost compared with smaller packs. Encrypted checkout helps protect personal information during payment.

Availability and Substitutions

Availability varies by strength and presentation. Common listings include verapamil SR 120 mg, 180 mg, 240 mg, and 360 mg in sustained-release tablets or capsules. If a specific strength is temporarily unavailable, a prescriber may recommend an alternative strength, a different SR product, or another antihypertensive class. Pharmacy teams will contact the prescriber before any substitution.

Patient Suitability and Cost Saving Tips

Verapamil SR suits adults with hypertension who do not have contraindications such as advanced AV block without a pacemaker, severe hypotension, or decompensated heart failure. Patients with liver impairment may need closer monitoring. Those on multiple rate-slowing drugs need careful oversight.

• Ask about a 60- to 90-day supply to reduce per-unit costs.
• Keep a simple dosing routine to support adherence.
• Set refill reminders so orders arrive before running low.
• Bundle eligible prescriptions to consolidate shipping.
• Review blood pressure readings with the clinic before dose changes.

Questions to Ask Your Clinician

• Which verapamil SR strength is appropriate to start: 120 mg, 180 mg, 240 mg, or 360 mg?
• Should the dose be taken with food, and at what time each day?
• What signs of low blood pressure or slow heart rate should prompt contact with the clinic?
• Are any current medicines risky to combine with verapamil, including beta blockers or digoxin?
• Would another calcium channel blocker or a different class suit the treatment goals?
• What is the plan if constipation or swelling becomes troublesome?
• How often should blood pressure and pulse be monitored during titration?

Authoritative Sources

• DailyMed: Verapamil Extended-Release
• FDA Drugs@FDA: Verapamil
• Health Canada: Drug Product Database

See current Verapamil SR pricing and place an order with prompt US delivery from Canada.