Please note: a valid prescription is required for all prescription medication.
Zeniquin Veterinary Antibiotic Overview and Safety
Start 2026 with savings: Use code SAVE10 for 10% OFF all RX meds. Jan–1 Mar. Ozempic from Canada and Mounjaro Vial not included. Offer valid until March 1st. Coupon code cannot be combined with other offers. For products with “Bulk Savings”, the discount will be applied to the regular price for 1 unit. Maximum allowable quantity equal to a 90 day supply per single order.
Price range: $259.99 through $676.99
You save


Zeniquin is a prescription veterinary antibiotic that contains marbofloxacin, a fluoroquinolone (broad-spectrum antibacterial) medicine. Veterinarians may prescribe it for certain bacterial infections in dogs and, in some cases, cats under extra-label use rules. Some patients explore Ships from Canada to US options when a veterinarian provides a valid prescription and regulations allow; this page summarizes uses, dosing basics, safety, and handling.
What Zeniquin Is and How It Works
This medicine is a fluoroquinolone antibiotic used in veterinary care. It works by inhibiting bacterial DNA enzymes (DNA gyrase and topoisomerase IV), which bacteria need to replicate and repair genetic material. As a result, susceptible bacteria may be killed or their growth may be stopped, depending on the organism and drug exposure. CanadianInsulin operates as a prescription referral service and does not dispense medications directly.
Marbofloxacin is not effective for viral or fungal illnesses, and it is not meant for routine “just in case” use. Clinicians often consider culture and sensitivity testing (lab testing that identifies the bacteria and which antibiotics work) when infections are recurrent or treatment has failed. Pet Medications can be browsed to understand other veterinary therapies that may be used alongside antibiotics.
Who It’s For
This antibiotic may be prescribed for dogs with confirmed or strongly suspected bacterial infections where a fluoroquinolone is appropriate, such as certain skin and soft-tissue infections or urinary tract infections. The exact indication depends on the animal’s symptoms, exam findings, and local resistance patterns. In many clinics, fluorooroquinolones are reserved for infections where other antibiotic options are unlikely to work.
Use may be limited or avoided in specific situations. Many fluoroquinolones are generally avoided in growing animals because of concerns about effects on cartilage and joints, and caution is often advised in pets with a history of seizures or other neurologic disorders. Cats may receive marbofloxacin only when a veterinarian determines it is suitable, and extra attention may be needed if there are other health issues. If your pet also has endocrine disease such as diabetes, it can help to review broader care needs in Identify Feline Canine Diabetes so changes in appetite, drinking, or activity are interpreted in context.
Dosage and Usage
Dosing for marbofloxacin is typically based on body weight and the infection being treated. Many regimens are given once daily for a veterinarian-determined duration, but the schedule and total course can differ by diagnosis, severity, and response. Tablets are usually given by mouth; some pets take them with food to reduce stomach upset, while others are directed to take them on an empty stomach based on the veterinarian’s instructions.
Why it matters: Skipping doses or stopping early can increase the chance of relapse and resistance.
For safe day-to-day use, common label-aligned practices include:
- Follow the prescribed schedule: keep timing consistent.
- Finish the full course: unless the veterinarian changes it.
- Watch hydration and appetite: note meaningful changes.
- Call the clinic for vomiting: especially if persistent.
If your pet has a chronic condition, antibiotic side effects can overlap with disease symptoms. For background on recognizing systemic illness changes in dogs, Diabetes Dogs Signs Symptoms can be a helpful reference for monitoring basics without replacing veterinary advice.
Strengths and Forms
Zeniquin is commonly supplied as oral tablets in multiple strengths so veterinarians can better match a weight-based dose. Availability can vary by jurisdiction and pharmacy sourcing, and not every strength is stocked everywhere. If a pet is between sizes, clinicians may use tablet splitting only when the product is designed for that use and the prescriber considers it appropriate.
The treatment is generally described and dispensed by tablet strength rather than by volume. Typical presentations include:
| Form | Common strengths | Notes |
|---|---|---|
| Oral tablet | 25 mg | Often used for small pets |
| Oral tablet | 50 mg | Intermediate strength |
| Oral tablet | 100 mg | Often used for larger dogs |
Ask the prescribing clinic to confirm the exact strength, tablet appearance, and directions, especially if multiple medications look similar at home.
Storage and Travel Basics
Store tablets at controlled room temperature unless the label states otherwise. Keep the medicine in the original container with the label intact, protected from moisture and direct light. As with all veterinary antibiotics, store it out of reach of children and animals to reduce the risk of accidental ingestion.
Quick tip: Keep a photo of the prescription label for reference during travel.
When traveling, maintain a stable environment and avoid leaving medications in a hot car or freezing conditions. If your pet has other time-sensitive therapies, plan packing so each medication stays in its recommended range. Owners managing multiple conditions sometimes benefit from a written checklist; for pets living with diabetes, Managing Pet Diabetes includes practical routines that can be adapted to multi-medication households.
Side Effects and Safety
Like many antibiotics, this treatment may cause gastrointestinal effects such as decreased appetite, nausea, vomiting, or diarrhea. Some pets also seem less energetic for a short period. Mild signs can sometimes be monitored while continuing the course, but persistent vomiting, repeated diarrhea, or refusal to eat should be discussed with the veterinary clinic promptly because dehydration and missed doses can complicate recovery.
More serious concerns may include allergic-type reactions (facial swelling, hives, sudden itching, trouble breathing), neurologic effects (tremors, disorientation, seizures), or other unexpected changes that are abrupt or severe. With any fluoroquinolone, veterinarians may be cautious in young, rapidly growing animals due to joint-related risks. If your pet has diabetes, reduced appetite or vomiting can also change glucose control; the guide Hyperglycemia In Dogs provides general context on when illness can affect glucose trends.
If a cat is prescribed Zeniquin under veterinary direction, report any sudden behavior or vision-related changes urgently. Do not restart a dose after a severe reaction unless the prescriber specifically instructs it.
Drug Interactions and Cautions
Fluoroquinolones can interact with products that bind medications in the gut. Antacids and supplements containing calcium, magnesium, aluminum, iron, or zinc may reduce absorption if given close together, and sucralfate can have a similar effect. If your pet receives these products, ask the veterinarian or pharmacist about spacing doses to avoid reducing antibiotic exposure.
Use extra caution in pets with seizure disorders, significant kidney or liver disease, or those receiving multiple medications with central nervous system effects. Always share a complete medication list, including supplements and flea/tick products, because “non-prescription” items can still matter. For owners balancing antibiotics alongside insulin therapy, Insulin Dogs offers background terms that can help when discussing a full medication schedule with the clinic.
Compare With Alternatives
Veterinarians choose antibiotics based on the suspected infection site, likely organisms, prior antibiotic exposure, and local resistance patterns. For uncomplicated cases, clinicians may consider other classes first, such as beta-lactams (for example, amoxicillin-clavulanate), first-generation cephalosporins (for example, cephalexin), tetracyclines (for example, doxycycline), or other options guided by culture results. Each has different coverage, side effect profiles, and dosing schedules.
Fluoroquinolones like marbofloxacin are often reserved for infections where narrower options are unlikely to be effective or when lab testing supports their use. If infections recur, the next step may include urine culture, skin cytology, imaging, or evaluation for underlying problems that predispose to infection. For households managing chronic disease risk factors, Preventing Diabetes Dogs Cats is one example of a general wellness resource that can complement veterinary follow-up.
Pricing and Access
Access to prescription veterinary antibiotics depends on a valid prescription and local rules for dispensing. Coverage varies by plan and region; some pet insurance policies reimburse eligible prescriptions, while others exclude them or require documentation. Cash-pay considerations can include the prescribed strength, duration, and whether a generic equivalent is allowed by the prescriber. For some households, the practical question is managing the full course without insurance, which can make verifying the exact quantity and refill rules important before starting.
CanadianInsulin can help route prescription details for review and, where permitted, licensed partner pharmacies handle dispensing and fulfillment. Documentation requirements may include the prescriber’s information, the patient (pet) details, and confirmation of directions so the pharmacy can dispense the correct strength and quantity. If you are comparing options, Promotions can be reviewed for general program information, noting that availability and eligibility can vary by jurisdiction.
Authoritative Sources
For the most accurate indications, precautions, and administration instructions, rely on the product label and your veterinarian’s directions. Antibiotic selection also depends on local bacterial resistance patterns and test results, which are not captured in general summaries.
These references provide additional context on fluoroquinolones and veterinary approvals:
For FDA animal drug labeling context, see Animal Drugs at FDA.
For fluoroquinolone class information, see Merck Veterinary Manual.
When permitted, handling may involve prompt, express, cold-chain shipping based on pharmacy requirements.
This content is for informational purposes only and is not a substitute for professional medical advice.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
What is Zeniquin used for in dogs?
Veterinarians may prescribe Zeniquin for certain bacterial infections in dogs when marbofloxacin is an appropriate choice. It is commonly considered for infections such as some urinary tract infections or skin and soft-tissue infections, depending on suspected bacteria and test results. It is not a treatment for viral illnesses, fungal infections, or non-infectious inflammation. Your veterinarian may recommend diagnostic testing (such as culture and sensitivity) when infections recur, are severe, or have not responded to other antibiotics.
Can Zeniquin be used in cats?
A veterinarian may sometimes prescribe marbofloxacin to cats under extra-label use, depending on the clinical situation and local regulations. Cats can be more sensitive to medication side effects, and the prescriber will weigh infection severity, other health conditions, and alternative antibiotics. If a cat is prescribed this medicine, follow the exact directions and report significant appetite changes, vomiting, diarrhea, unusual behavior, or any sudden vision-related concerns promptly. Only a veterinarian can determine if it is appropriate for an individual cat.
How is Zeniquin typically given?
This medication is usually given by mouth as a tablet, with a dose selected based on body weight and the infection being treated. Many regimens are administered once daily, but the schedule and total course length can differ. Some pets take the tablet with a small amount of food to reduce stomach upset, while others are directed differently by the prescriber. Give it exactly as prescribed and complete the full course unless your veterinarian changes the plan based on response or side effects.
What should I do if I miss a dose of Zeniquin for my pet?
If a dose is missed, contact your veterinary clinic for instructions that fit your pet’s schedule and medical history. In many cases, the clinic may advise giving the missed dose when remembered and then returning to the regular timing, but this is not always appropriate if the next dose is soon. Avoid giving two doses at once unless a veterinarian specifically instructs it. Keeping a simple medication log can reduce missed doses, especially when multiple treatments are used.
What side effects should I watch for while my pet is taking Zeniquin?
Common side effects with fluoroquinolone antibiotics can include decreased appetite, vomiting, diarrhea, or mild lethargy. More serious concerns may include allergic reactions (swelling, hives, breathing trouble), neurologic signs (tremors, disorientation, seizures), or other sudden, severe changes. Puppies and other growing animals may be at higher risk for joint-related issues with this drug class, so veterinarians may avoid use in that group. Report significant or worsening symptoms promptly to the prescribing clinic.
Can supplements or antacids interfere with Zeniquin?
Yes. Products containing calcium, magnesium, aluminum, iron, or zinc can bind fluoroquinolones in the gastrointestinal tract and reduce absorption if given too close together. Sucralfate may have a similar effect. If your pet takes mineral supplements, antacids, or gastrointestinal protectants, ask the veterinarian or pharmacist how to separate dosing times. Also share a complete medication list, including non-prescription items, because interactions can be missed when only prescription drugs are discussed.
What should I ask my veterinarian before starting Zeniquin?
Helpful questions include: what infection is being treated, whether a culture and sensitivity test is recommended, and what signs suggest the treatment is working. Ask about the planned duration, what to do if vomiting or diarrhea occurs, and whether your pet’s age or growth status affects safety. If your pet has kidney disease, liver disease, neurologic conditions, or diabetes, confirm any extra monitoring steps. Also ask whether other medications or supplements should be spaced apart to avoid reducing antibiotic absorption.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
You Might Also Like
Related Articles
Zepbound Pill Clarified: Injection Reality and Oral Research
Key Takeaways Current form: Zepbound is an injectable medicine, not a tablet. Search intent: “pill” usually means convenience, not a new product. Dosing language: labels use stepwise titration and maintenance…
Lancets For Blood Sugar Testing: Selection And Safety Tips
OverviewFingerstick blood glucose checks rely on small, sharp tools and consistent technique. In most home setups, a spring-loaded lancing device uses lancets to puncture skin and produce a drop of…
SGLT2 Inhibitors Explained: Uses, Risks, and Examples
Key Takeaways These medicines lower blood sugar by acting in the kidneys. Some are also labeled for heart failure or chronic kidney disease. Drug names include dapagliflozin, empagliflozin, and canagliflozin.…
Out Of Pocket Cost For GLP-1 Medications: Planning Tips
Key Takeaways Costs vary by drug, indication, and dose form Cash-pay totals include more than the pen Programs exist, but eligibility is limited Be cautious with compounded versions and unverifiable…


