Please note: a valid prescription is required for all prescription medication.
Zeniquin® is a prescription antibiotic for dogs and cats. The tablet contains marbofloxacin used to treat susceptible bacterial infections of the skin, soft tissue, urinary tract, and respiratory tract. CanadianInsulin ships from Canada with US delivery from Canada and Canadian pricing, which may help when buying Zeniquin without pet insurance.
See Zeniquin price and compare strengths, then place an order online with US shipping. This guide explains how Zeniquin marbofloxacin tablets work, who they suit, and safe use basics.
At CanadianInsulin, orders are filled by licensed Canadian pharmacies after we confirm a valid prescription with your clinic.
What Zeniquin® Is and How It Works
Zeniquin® contains marbofloxacin, a fluoroquinolone antibiotic. It is bactericidal. It blocks bacterial enzymes needed for DNA replication and repair. This action helps clear infections caused by susceptible gram-negative and some gram-positive organisms.
Veterinarians use marbofloxacin for skin and soft tissue infections, wound infections, urinary tract infections, and certain respiratory infections in dogs and cats. It is not effective for viruses, fungi, or parasites. Culture and susceptibility testing can guide therapy when available.
Zeniquin marbofloxacin tablets are given once daily in most cases. The once-daily schedule may improve adherence for multi-week courses. For a broader overview of choices in this class and others, see our Pet Antibiotics guide.
Who Zeniquin® Is For
Zeniquin tablets for dogs and Zeniquin for cats tablets are indicated for infections proven or strongly suspected to be caused by susceptible bacteria. Veterinarians consider it when first-line options are unsuitable or when culture results favor a fluoroquinolone.
Do not use in growing animals. Fluoroquinolones may affect developing cartilage. Avoid use in dogs under 12 months of age, and in large or giant breeds until skeletal maturity (often up to 18 months). Avoid use in cats under 12 months. Use caution in animals with seizure disorders or known hypersensitivity to quinolones. Discuss pregnancy, breeding status, and any chronic illnesses with the veterinarian.
Many uncomplicated skin or urinary infections may also respond to penicillins or cephalosporins. For context on a common first-line choice, see our Clavamox Guide.
Dosage and Usage
Follow the veterinarian’s prescription and the approved label. A commonly referenced dose for dogs and cats is 2.75 mg/kg once daily. In some cases, the veterinarian may prescribe up to 5.5 mg/kg once daily. Duration depends on infection site, severity, and clinical response.
Administer Zeniquin marbofloxacin tablets with or without food. If stomach upset occurs, giving with a small meal may help. Provide access to water. Do not exceed the prescribed dose or duration. Antibiotic courses typically continue several days beyond the resolution of clinical signs to reduce relapse risk.
Separate administration from antacids, sucralfate, iron, or calcium-containing supplements, which can reduce absorption. Consult the veterinarian before combining with other medicines.
Strengths and Forms
Zeniquin marbofloxacin tablets are film-coated tablets intended for oral use in dogs and cats. Commonly available strengths include:
- Zeniquin 25 mg tablets
 - Zeniquin 50mg tablets
 - Zeniquin 100mg tablets
 
Availability may vary by batch and by pharmacy. Prescriptions often note exact strengths and quantity to match the animal’s weight and dose. For cats, marbofloxacin 25 mg tablets for cats are frequently used. For larger dogs, marbofloxacin 100mg tablets for dogs may be prescribed.
Missed Dose and Timing
If a dose is missed, administer it when remembered unless the next dose is near. If it is close to the next scheduled dose, skip the missed dose. Do not double doses. Keep a consistent once-daily schedule when possible.
Storage and Travel Basics
Store your tablets at room temperature in the original, closed container. Protect from moisture and excessive heat. Keep out of reach of children and animals.
When traveling, keep your Zeniquin in the labeled container along with a copy of the prescription. Pack enough tablets for the full course plus a small buffer in case of unexpected delays. Avoid leaving medicine in a hot vehicle.
Benefits
Zeniquin tablets for dogs and cats offer once-daily dosing, broad antibacterial coverage within the fluoroquinolone class, and labeled use for several common veterinary infections. The tablet format allows precise dosing across multiple strengths to suit different body weights. Treatment guided by culture and susceptibility can improve outcomes and stewardship.
Side Effects and Safety
- Gastrointestinal upset such as vomiting, soft stool, or decreased appetite
 - Lethargy or reduced activity
 - Localized irritation if a tablet is chewed and tastes bitter
 - Restlessness or agitation in sensitive animals
 
Serious effects are uncommon but can occur. Fluoroquinolones may cause cartilage abnormalities in growing animals. Neurologic signs, including tremors or seizures, are possible, especially in animals with seizure disorders or when combined with certain drugs. Hypersensitivity reactions are rare but require urgent veterinary attention. Stop the drug and contact the veterinarian if severe adverse effects develop.
Drug Interactions and Cautions
Separate dosing from antacids, sucralfate, and mineral supplements containing aluminum, magnesium, calcium, or iron. These can bind marbofloxacin and lower absorption. Use caution with NSAIDs in animals predisposed to seizures. Interactions with theophylline and similar drugs may require added monitoring. Always provide the veterinarian a complete list of medicines, supplements, and diets.
Do not use in animals known to be hypersensitive to fluoroquinolones. Use caution in animals with central nervous system disorders. Discontinue and seek veterinary care if concerning neurologic signs occur. For information on other antibiotic classes used in small animals, see our Azithromycin Guide.
What to Expect Over Time
Clinical signs often start to improve within a few days once effective therapy begins. Appetite, comfort, and energy may gradually return as the infection responds. Complete the full prescribed course even if signs improve early. Recheck examinations or tests may be needed to confirm resolution, especially for deep or recurrent infections.
Compare With Alternatives
Veterinarians may consider other approved options based on infection site, culture results, safety, and prior response:
- Baytril® (enrofloxacin), another fluoroquinolone often used for skin, urinary, and respiratory infections.
 - Clavamox® (amoxicillin and clavulanate), a common first-line for many uncomplicated skin and urinary infections.
 - Cephalexin, a cephalosporin used for skin and soft tissue infections; see our Cephalexin Guide for details.
 
Choice depends on the organism, susceptibility, site penetration, and the animal’s medical history.
Pricing and Access
Canadian pricing is available, and Zeniquin from Canada ships to the US. Check Zeniquin cost by strength and quantity before placing an order. Many customers evaluate the Zeniquin cash price when paying out of pocket. You can place an order online, upload the prescription, and select US shipping. Explore more veterinary categories on our Pet Medications page.
Prescriptions are required and verified before dispensing. Encrypted checkout protects payment details.
Availability and Substitutions
Availability can vary by strength. If a requested strength is unavailable, a prescriber may adjust to another labeled strength to achieve the same daily dose. When oral therapy is not appropriate, injectable options may be considered in clinic settings; see our editorial overview on Baytril Injection for context on fluoroquinolone use by injection in cats.
If Zeniquin is not appropriate or available, the veterinarian may recommend a different class such as penicillins, cephalosporins, tetracyclines, or macrolides, guided by culture results and clinical judgment.
Patient Suitability and Cost Saving Tips
Suitable candidates include adult dogs and cats with infections likely caused by susceptible bacteria, especially when culture or prior response suggests a fluoroquinolone. It is not suitable for growing puppies, kittens, or animals with known quinolone hypersensitivity. Caution is warranted in animals with seizure disorders.
To help manage costs, ask the clinic about a multi-week plan that matches the full expected course, which may reduce per-tablet cost. Ordering refills together with other needed pet therapies can lower shipping cost per item. Zeniquin US shipping from Canada supports access for households comparing Zeniquin Canadian pricing.
Questions to Ask Your Clinician
- Is culture and susceptibility testing recommended for this infection?
 - What dose and duration are planned, and what signs should prompt a recheck?
 - Can this medicine be given with food or other routine supplements?
 - Are there specific side effects to watch for in this animal?
 - What alternatives exist if the infection does not respond as expected?
 - When should follow-up labs or imaging be scheduled?
 
Authoritative Sources
- Zoetis: Zeniquin Product Information
 - FDA Animal Drugs (CVM) Search
 - Health Canada Drug Product Database
 
Start your order for Zeniquin with US delivery from Canada and Canadian pricing.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
 - Cold-Packed Products $35.00
 
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
 - Not available for Cold-Packed products
 
What infections does Zeniquin treat?
Zeniquin (marbofloxacin) treats susceptible bacterial infections in dogs and cats. Common uses include skin and soft tissue infections, urinary tract infections, and some respiratory infections. It does not treat viral, fungal, or parasitic diseases.
Can Zeniquin be given with food?
Yes. It can be given with or without food. If stomach upset occurs, giving the dose with a small meal may help. Provide access to fresh water.
How long is a typical Zeniquin course?
Duration varies by infection site, severity, and response. Many courses last one to several weeks and continue a few days beyond clinical improvement. Follow the veterinarian’s directions and recheck if advised.
Is Zeniquin safe for puppies or kittens?
Avoid use in growing animals. Fluoroquinolones can affect developing cartilage. Do not use in dogs under 12 months (up to 18 months for large or giant breeds) or cats under 12 months unless the veterinarian determines benefits outweigh risks.
What side effects should be watched for?
Possible effects include vomiting, soft stool, reduced appetite, or lethargy. Rarely, neurologic signs such as tremors or seizures can occur, especially in predisposed animals. Stop the drug and contact the veterinarian if severe signs develop.
How do I order Zeniquin online from Canada?
Place an order on CanadianInsulin, upload the prescription, and choose US shipping. After clinic verification, a licensed Canadian pharmacy dispenses and ships your medicine.
Can Zeniquin be used with other medicines?
Separate from antacids, sucralfate, and mineral supplements that contain aluminum, magnesium, calcium, or iron. Use caution with NSAIDs and theophylline in predisposed animals. Provide the veterinarian a complete medication list before starting.
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