Trulicity

Trulicity (dulaglutide) is a once-weekly injectable medication used to improve blood sugar control in adults with type 2 diabetes. It works by stimulating the body to produce more insulin when blood sugar is high and slowing down the release of sugar from the liver. Trulicity also helps reduce the risk of cardiovascular events in people with type 2 diabetes.

Benefits:

• Helps lower blood sugar levels in adults with type 2 diabetes
• Reduces the risk of heart attack, stroke, and cardiovascular death in people with type 2 diabetes
• Supports weight loss by reducing appetite
• Convenient once-weekly injection
• Improves HbA1c levels when used as part of a comprehensive diabetes management plan

Dosage:

• The typical starting dose of Trulicity is 0.75 mg once a week.
• After 4 weeks, the dose may be increased to 1.5 mg once a week, depending on your doctor’s recommendation.
• If additional blood sugar control is needed, the dose may be increased to 3 mg, 4.5 mg, or 6 mg once a week.

Warnings and Precautions:

• Trulicity may increase the risk of thyroid tumors, including medullary thyroid carcinoma (MTC). Avoid it if you have a family history of thyroid cancer or MEN 2.
• Trulicity may cause pancreatitis. Seek medical attention if you experience severe abdominal pain, nausea, or vomiting.
• Dehydration can worsen kidney function. Stay hydrated and inform your doctor of any changes in urination or swelling.
• Trulicity can cause nausea, vomiting, and diarrhea, especially when starting treatment.
• Rapid blood sugar control may worsen diabetic retinopathy. Regular eye exams are recommended.
• Seek immediate medical help if you experience difficulty breathing or swelling of the face or throat.
• Not for type 1 diabetes or diabetic ketoacidosis.
• Not recommended unless prescribed by a healthcare provider.

Usage Instructions:

• Inject Trulicity once a week, on the same day each week
• It can be taken at any time of the day, with or without food
• Administer the injection subcutaneously (under the skin) in the thigh, abdomen, or upper arm
• Rotate injection sites to avoid skin irritation
• Do not reuse needles; use a new needle for each injection

Storage Information:

• Store Trulicity in the refrigerator at 36°F to 46°F (2°C to 8°C)
• If needed, Trulicity can be kept at room temperature (up to 86°F or 30°C) for up to 14 days before using
• Do not freeze the medication
• Keep the medication out of direct sunlight and out of reach of children

Common Side Effects:

• Nausea is a common side effect that may occur when starting Trulicity.
• Some people may experience diarrhea.
• Vomiting can occur, especially in the early stages of treatment.
• Abdominal pain may be felt as a result of the medication.
• Decreased appetite is another possible side effect.
• Fatigue is also commonly reported by some users of Trulicity. 

More information about Trulicity

• Product Monograph – Health Canada
• U.S. Food and Drug Administration Medication Guide