Onglyza (Saxagliptin) dosage

The recommended dosage of Onglyza is either 2.5 mg or 5 mg once a day.

If you have renal impairment or a history of kidney problems, you should not take Saxagliptin. Your dose of this medication will likely be 2.5 mg per day if you have had some kidney trouble, but it should only be taken following full renal assessment by your doctor or health care provider.

A dose of 2.5 mg of Onglyza may be taken with a strong cytochrome P450 3A4/5 (CYP3A4/5) inhibitor, such as atazanavir, ketoconazole, telithromycin, itraconazole, indinavir, nelfinavir, nefazodone, saquinavir, ritonavir, and clarithromycin.

When the medication is taken with sulfonylurea or insulin, the dose of insulin will need to be lowered to reduce the risk of hypoglycemia.

How to use Saxagliptin

Always make sure you read and understand the information leaflet before you take Onglyza. If you are not sure how to take it or have any questions, you should call your doctor.

The medication comes in tablet form and can be taken with or without food. It should be swallowed whole and should not be crushed or cut unless specifically directed by your doctor or health care provider. Try to take the medication at the same time each day, as this medication will work best on a schedule. You should not skip doses. If you do forget to take a dosage, take it as soon as possible, but do not take double or extra doses.

If this medication is not effective, or if you start to feel unwell (blood sugar too high or too low) while taking this type of medication, tell your doctor right away.

Disclaimer: Please note that the contents of this community article are strictly for informational purposes and should not be considered as medical advice. This article, and other community articles, are not written or reviewed for medical validity by Canadian Insulin or its staff. All views and opinions expressed by the contributing authors are not endorsed by Canadian Insulin. Always consult a medical professional for medical advice, diagnosis, and treatment.