Eliquis® Tablets for Atrial Fibrillation

Apixaban is an oral anticoagulant used to prevent harmful blood clots. It lowers stroke risk in atrial fibrillation and treats deep vein thrombosis and pulmonary embolism. This page explains how the medicine works, safety basics, and ways to compare access without insurance.

What Eliquis Is and How It Works

Apixaban is a direct Factor Xa inhibitor that reduces thrombin generation and clot formation. It is used for nonvalvular atrial fibrillation stroke prevention, treatment of deep vein thrombosis and pulmonary embolism, and for postsurgical venous thromboprophylaxis. This class works by selectively blocking activated Factor X, which helps keep blood from clotting too easily. For background on the condition, see Atrial Fibrillation. US shipping from Canada is available through our referral network.

Eliquis® is the reference brand for apixaban. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

Effectiveness and safety depend on correct use and careful monitoring for bleeding. The treatment may be combined with other preventive steps per the product label. Some readers also compare apixaban cost when considering long-term access.

Who It’s For

This medicine is indicated for adults who need anticoagulation to reduce the risk of stroke and systemic embolism in nonvalvular atrial fibrillation, to treat DVT and PE, and to reduce the risk of recurrent DVT/PE after initial therapy. It is also used for prevention of venous clots after hip or knee replacement.

It may not be appropriate in patients with active pathological bleeding or a known hypersensitivity to the drug. Use can be limited or avoided in significant hepatic disease associated with coagulopathy. Caution is advised with severe renal impairment and in older adults with multiple risk factors for bleeding. Discuss pregnancy and breastfeeding with a healthcare professional.

Dosage and Usage

Tablets are typically taken twice daily, with or without food. For clot treatment, the initial period may involve a higher total daily amount before moving to a maintenance routine, as described in the official label. Postsurgical prevention generally follows a fixed schedule for a defined duration. Timing may change around invasive procedures per clinician direction.

Swallow tablets whole with water. If switching from another anticoagulant, follow the label-based transition approach advised by your prescriber. Do not start, stop, or adjust on your own. Refer to the FDA or Health Canada product information for full instructions.

Strengths and Forms

Film-coated oral tablets are commonly available in 2.5 mg and 5 mg strengths. Availability can vary by pharmacy and manufacturer.

Missed Dose and Timing

If a dose is missed, take it as soon as remembered the same day. If it is almost time for the next dose, skip the missed dose and resume the regular schedule. Do not take two doses at once. Try to take doses at consistent times to support steady protection.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from heat and direct light. Keep the bottle tightly closed and out of reach of children and pets. Do not store in a bathroom cabinet where humidity is high.

When traveling, keep tablets in the original labeled container inside a carry-on. Bring a copy of the prescription and a medication list. If crossing borders, allow extra time for screening and keep documentation accessible. Pack enough supply for the entire trip plus a small buffer. If your prescriber updates dosing, bring written instructions.

Benefits

This therapy offers predictable anticoagulation without routine lab monitoring for most patients. Twice-daily dosing supports steady blood levels. Fewer food interactions than vitamin K antagonists can simplify daily routines. It may be used for both treatment and prevention settings, reducing pill burden during transitions.

Side Effects and Safety

• Bleeding gums
• Nosebleeds
• Easy bruising
• Prolonged bleeding from cuts
• Fatigue or weakness
• Nausea

Serious bleeding can occur, including gastrointestinal or intracranial bleeding. Spinal or epidural hematomas may arise in patients receiving neuraxial anesthesia or spinal puncture. Seek urgent care for severe or unexpected bleeding, dizziness with fainting, severe headache, or signs of stroke. Hypersensitivity reactions are rare but possible.

Learn more in our overview of adverse reactions: Apixaban Side Effects.

Drug Interactions and Cautions

Strong dual inhibitors of CYP3A4 and P-gp can increase exposure, while strong inducers can reduce it. Concomitant use with other anticoagulants, antiplatelet drugs, NSAIDs, SSRIs, or SNRIs may raise bleeding risk. Herbal products such as St. John’s wort can alter effect. Alcohol may increase bleeding risk. Always share a full medication list with your prescriber and pharmacist.

Patients with artificial heart valves or certain valvular conditions should ask a specialist about appropriate therapy. For planned spinal or epidural procedures, coordinate timing carefully to reduce hematoma risk.

What to Expect Over Time

Protection begins when the medicine reaches active levels and continues only while doses are taken as directed. Most patients will not feel a difference day to day; benefit is preventive. Missing doses can reduce protection. Keep a reminder system to support adherence. Discuss any planned surgeries or dental work well ahead of time so your care team can manage therapy transitions safely.

Compare With Alternatives

Other oral anticoagulants may be considered based on clinical factors and preference. Rivaroxaban is a once-daily Factor Xa inhibitor; see Xarelto. Dabigatran is a direct thrombin inhibitor and a capsule formulation; see Pradaxa. Warfarin remains an option when frequent INR monitoring is acceptable or necessary. Your clinician will match therapy to your medical history and goals.

Pricing and Access

Canadian pricing can help reduce out-of-pocket burden for long-term therapy, with US delivery from Canada available for eligible prescriptions. Many patients look at apixaban cost to plan budgets, though final amounts depend on quantity, manufacturer, and pharmacy.

Review current Apixaban price Canadian pricing on our product page to compare options. Checkout is encrypted. For potential savings events, visit our Promotions page.

Patients paying cash sometimes review Eliquis price no insurance from Canada against local quotes. Your final total can vary by prescriber directions and fill intervals.

Availability and Substitutions

Supply can vary by manufacturer. If your selected presentation is unavailable, a prescriber may recommend a suitable alternative in the same class or another anticoagulant approved for your condition. Some individuals compare Apixaban price cash price from Canada when evaluating substitutes. For details on generic status and options, see Apixaban Generic Available.

Patient Suitability and Cost-Saving Tips

Not everyone is a candidate for this therapy. A history of significant bleeding, recent major surgery, uncontrolled hypertension, or severe liver disease may change suitability. Older adults, those with kidney impairment, and those on interacting medicines require extra caution. Always confirm appropriateness with your prescriber before starting.

To reduce ongoing expense, consider a longer fill interval if appropriate, and align refills with clinic visits. Set reminders to prevent gaps in therapy. Patients comparing options may look at Generic apixaban cost ships to US when deciding on fills and quantities. For practical strategies, read Save On Apixaban Cost.

Questions to Ask Your Clinician

• Therapy goal: how anticoagulation fits my risks
• Bleeding plan: what to watch for and when to seek care
• Procedures: timing around dental or surgical work
• Other medicines: managing NSAIDs and antiplatelets
• Monitoring: follow-up schedule and lab needs
• Monthly budget: discuss Apixaban cost per month from Canada vs local options

Authoritative Sources

FDA DailyMed: Apixaban Prescribing Information

Manufacturer Site: Eliquis (Apixaban)

Health Canada Drug Product Database: Apixaban

Who It’s For

For clot treatment and prevention beyond atrial fibrillation, review Pulmonary Embolism guidance and follow your prescriber’s plan.

Benefits

Read a concise overview of clinical uses here: Primary Apixaban Uses.

Ready to proceed? You can place an order through CanadianInsulin for Ships from Canada to US with prompt, temperature-controlled handling when required. This information is for educational purposes and does not replace advice from your healthcare professional.