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Eliquis® Tablets for Atrial Fibrillation and DVT/PE
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Apixaban is an oral anticoagulant that reduces the risk of harmful blood clots. It helps prevent stroke in certain heart rhythm disorders and treats or prevents deep vein thrombosis and pulmonary embolism. This page outlines clinical uses, safety, and factors that influence apixaban cost so you can discuss options with your prescriber.
What Eliquis Is and How It Works
US delivery from Canada is available for eligible prescriptions through our platform. CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order. You can review access options and typical savings without insurance in the sections below.
Eliquis® contains apixaban, a direct factor Xa inhibitor. By blocking factor Xa, it reduces thrombin generation and clot formation. This class offers predictable anticoagulation and does not require routine INR monitoring. Talk with your clinician about your risks and goals, because the balance between clot prevention and bleeding must be individualized.
When comparing options, some users consider apixaban price alongside clinical fit. Always weigh cost with safety, dosing convenience, and your overall treatment plan.
Who It’s For
This medicine is used in adults to reduce the risk of stroke and systemic embolism in nonvalvular atrial fibrillation. It also treats acute deep vein thrombosis or pulmonary embolism and helps prevent recurrence after initial therapy. Another approved use is prevention of venous thromboembolism after hip or knee replacement surgery.
People with active pathological bleeding should not take this treatment. Those with artificial heart valves, certain severe liver problems, or very high bleeding risk may not be candidates. Discuss pregnancy, breastfeeding, and planned procedures with your prescriber before starting therapy.
If you want more background on the heart rhythm indication, see our overview of Atrial Fibrillation. For clot-related conditions, read about DVT and PE.
Dosage and Usage
The dosing schedule follows the approved label for each indication. Most long-term regimens use twice-daily dosing at consistent times. For acute clot treatment, an initial higher-intensity phase is followed by a maintenance phase. After orthopedic surgery, dosing usually begins 12 to 24 hours postoperatively, provided hemostasis has been achieved.
Swallow tablets with or without food. If swallowing is difficult, the tablet may be crushed and suspended in water, D5W, or apple juice, or mixed with applesauce, and taken promptly. Follow your prescriber’s directions exactly. Do not stop this medicine without medical guidance, as the risk of clotting can rise if therapy is interrupted.
Before any surgery, dental work, or spinal procedure, tell your healthcare team that you take a factor Xa inhibitor. Your prescriber may advise holding doses for an appropriate interval. The exact timing depends on bleeding risk of the procedure and your kidney function; always defer to the official label and clinician instructions.
Strengths and Forms
The treatment is supplied as film-coated oral tablets in commonly available strengths of 2.5 mg and 5 mg. Tablet color and imprint differ by strength to aid identification. Availability of specific presentations may vary by pharmacy and manufacturer.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember on the same day, then resume your regular schedule. Do not take two doses at once to make up for a missed dose. Set reminders or use a pill organizer to help keep your dosing consistent.
Storage and Travel Basics
Store tablets at room temperature in a dry place away from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. Do not use tablets that are damaged or show signs of deterioration.
When traveling, carry medicines in your hand luggage with the original label. Bring a copy of your prescription and your prescriber’s contact information. If crossing borders, allow extra time for security screening and keep medications accessible. Pack only what you need plus a small buffer, and set alerts to maintain your twice-daily schedule across time zones.
Benefits
Factor Xa inhibitors provide consistent anticoagulation with fixed dosing for most adults. They do not require routine blood tests like INR for standard use. Food interactions are more limited than with some older therapies, and there are fewer dietary restrictions. Onset and offset of effect are relatively quick, which can simplify perioperative planning compared with certain alternatives.
Side Effects and Safety
- Bruising or minor bleeding
- Nosebleeds or gum bleeding
- Heavier than usual menstrual bleeding
- Fatigue or weakness
- Nausea or mild stomach upset
- Headache or dizziness
Serious but less common risks include major bleeding, which can occur at any site. Seek immediate care for prolonged bleeding, black or bloody stools, coughing or vomiting blood, unusual severe headache, or symptoms of stroke. Spinal or epidural hematomas may occur in patients receiving neuraxial anesthesia or spinal puncture; this can cause long-term or permanent paralysis. Review the boxed warnings and all precautions on the official label.
Using this medicine with other drugs that affect clotting can increase bleeding risk. Alcohol misuse may add risk. Always tell each clinician and pharmacist that you take an anticoagulant, and carry a medical alert card if advised.
Drug Interactions and Cautions
Strong dual CYP3A4 and P-gp inhibitors, such as ketoconazole, itraconazole, or ritonavir, can increase apixaban exposure. Strong inducers like rifampin, carbamazepine, phenytoin, or St. John’s wort can reduce exposure and potentially reduce efficacy. Combining with antiplatelets, NSAIDs, or other anticoagulants may raise bleeding risk.
Kidney or liver impairment can affect selection and dosing. The elderly and those with low body weight may need additional consideration. Avoid abrupt discontinuation unless directed by your prescriber, and do not start or stop interacting medications without professional guidance.
For a deeper dive into uses and cautions, see Apixaban Uses and our practical guide on Eliquis Dosing Tips.
What to Expect Over Time
Anticoagulant effect begins within hours of dosing and continues with regular use. Most people will not “feel” the effect; success is measured by preventing clots and avoiding bleeding. Plan ahead for refills and appointments, and keep a list of all medicines and supplements to review at each visit.
Watch for signs of bleeding and report concerning symptoms right away. If your medical situation changes, such as new procedures or a hospital admission, inform the team about your anticoagulant therapy. Adherence matters; set alarms or pair dosing times with daily routines.
For practical safety tips, you can also review our article on Manage Apixaban Side Effects.
Compare With Alternatives
Other direct oral anticoagulants include rivaroxaban and dabigatran. Depending on your renal function, dosing preference, and concomitant medicines, a different agent may be recommended. Explore options like Xarelto or Pradaxa with your prescriber to see what fits your clinical profile.
Pricing and Access
We aim to make Canadian pricing transparent with clear product details and secure checkout. If you want to estimate your apixaban cost per month, compare per-tablet pricing across pack sizes and manufacturers. For the common strength, you can also check apixaban 5 mg price to gauge potential savings versus local cash rates.
Generic availability, tablet count, and manufacturer can influence apixaban generic cost. Coverage and copays vary widely, and apixaban cost medicare can differ by plan tier and pharmacy network. If you are exploring assistance options, see our practical tips in Eliquis Cost Tips and strategies to Save on Apixaban. For occasional offers, visit our Promotions page.
Orders are processed with encrypted checkout, and we offer US shipping from Canada on eligible prescriptions. Category browsing can help you compare related items in Cardiovascular.
Availability and Substitutions
Supply can vary by manufacturer. If a specific generic is unavailable, a pharmacist may dispense an equivalent product after confirming appropriateness. When comparing options, people often look at apixaban generic price in addition to tablet count, which can change the per-dose value.
If your prescriber recommends an alternative therapy instead, that decision will reflect your risks, benefits, and current medications. You can learn more about older therapies in our article Warfarin for Prevention.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults who need reliable anticoagulation without routine INR checks. It may not be appropriate for those with active bleeding, recent intracranial hemorrhage, or high-risk procedures pending. Your clinician weighs bleeding risk, kidney and liver function, drug interactions, and treatment goals.
To reduce out-of-pocket spending, consider longer fills if appropriate, use refill reminders, and compare generics from different manufacturers when available. For some payers, mail-order options can help. If you pay cash, track prices periodically, as markets can change. Generic apixaban cost can differ by tablet count and supplier.
For nursing and care coordination, see our professional overview on Apixaban Nursing Considerations.
Questions to Ask Your Clinician
- My indication: Which dosing schedule applies to me?
- Bleeding risk: What signs should prompt urgent care?
- Interactions: Which medicines or supplements should I avoid?
- Procedures: How long before a procedure should I hold doses?
- Duration: How long should I continue this therapy?
- Switching: If I need to switch, how is that managed safely?
Authoritative Sources
For full prescribing information, see the manufacturer’s resources from Bristol Myers Squibb on Eliquis; review them alongside your clinician’s advice: Official prescribing information from Bristol Myers Squibb. You can also consult the FDA label and Medication Guide for detailed safety information: FDA-approved label and Medication Guide for Eliquis. Health Canada provides additional product data in its database: Health Canada Drug Product Database entry for apixaban.
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What is apixaban used for?
It helps prevent stroke in nonvalvular atrial fibrillation and treats or prevents deep vein thrombosis and pulmonary embolism. It is also used after certain orthopedic surgeries to prevent clots.
How should I take apixaban?
Take it exactly as prescribed, usually twice daily at the same times. Swallow tablets whole or, if needed, crush and take in a small amount of liquid or applesauce promptly.
Can I stop apixaban if I feel fine?
Do not stop without medical advice. Stopping suddenly can raise the risk of blood clots. Speak with your prescriber before changing or interrupting therapy.
What if I miss a dose?
Take the missed dose as soon as you remember on the same day, then resume your regular schedule. Do not double up doses to catch up.
Are there foods I must avoid?
No specific diet is required for this medicine. However, limit alcohol and discuss herbal supplements or over-the-counter products that may affect bleeding risk.
Are there important interactions?
Yes. Strong CYP3A4 and P-gp inhibitors or inducers can alter drug levels. NSAIDs, antiplatelets, and other anticoagulants can increase bleeding risk. Always review all medicines with your clinician.
Is there a reversal agent?
A specific reversal agent may be used in certain emergency bleeding situations at specialized centers. Access is determined by hospital protocols and clinician judgment.
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