Brilinta® Tablets for Acute Coronary Syndrome

Brilinta® is ticagrelor, an oral antiplatelet used to help prevent blood clots after a heart attack or acute coronary syndrome. This page explains uses, dosing, safety, and how to access Canadian pricing with US delivery from Canada. It can help compare Brilinta price and cost, including options for those without insurance.

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What Brilinta® Is and How It Works

Brilinta is a P2Y12 platelet inhibitor. It helps stop platelets from clumping together and forming clots. Clinicians use it with low-dose aspirin to reduce the risk of cardiovascular death, heart attack, and stent thrombosis after acute coronary syndrome or percutaneous coronary intervention. Orders ship from Canada to the US after prescription verification.

Ticagrelor binds reversibly to the platelet P2Y12 receptor. This blocks ADP-mediated activation and lowers platelet aggregation. Its effect starts within hours of a loading dose and continues with twice-daily maintenance dosing. Antiplatelet action is stronger than clopidogrel in head-to-head trials, but bleeding risk can be higher.

Who Brilinta® Is For

Brilinta is indicated for adults with acute coronary syndrome, including unstable angina, NSTEMI, or STEMI. It is also used to reduce the risk of cardiovascular events in those with a history of myocardial infarction. Some patients with stable coronary disease and prior PCI may continue therapy as directed by their cardiology team.

Do not use Brilinta in patients with active pathologic bleeding or a history of intracranial hemorrhage. Avoid it in severe hepatic impairment. Use caution in patients with increased bleeding risk, recent trauma, peptic ulcer disease, or bradyarrhythmias without a pacemaker. Patients with asthma or COPD may experience dyspnea more often.

To learn more about the condition it treats, see Acute Coronary Syndrome.

Dosage and Usage

Typical ACS treatment starts with a 180 mg loading dose, then 90 mg twice daily with low-dose aspirin. After 12 months, many patients transition to 60 mg twice daily for long-term secondary prevention, taken with low-dose aspirin. The recommended aspirin dose is usually 75 to 100 mg daily. Higher aspirin doses can reduce ticagrelor effectiveness, based on label guidance.

Tablets are taken by mouth, with or without food. If swallowing is difficult, the tablet may be crushed and mixed in water, then taken promptly, as described in the official label. Always follow the prescriber’s directions and the product monograph. For dosing background, see Ticagrelor 90 Mg.

Strengths and Forms

Brilinta is available as oral tablets in commonly published strengths:

• 90 mg tablets for initial maintenance therapy after ACS
• 60 mg tablets for ongoing secondary prevention after the first year

Availability may vary by pharmacy and country. Canadian packaging and tablet appearance can differ from US versions.

Missed Dose and Timing

If a dose is missed, take the next dose at the regular scheduled time. Do not take two doses at once to make up for a missed dose. Consistent dosing supports steady platelet inhibition.

Storage and Travel Basics

Store tablets at room temperature, typically 68 to 77°F (20 to 25°C). Keep them dry and in the original container with the label. Protect from excessive heat and moisture. For travel, carry your medication in a hand bag, keep it in its labeled bottle, and bring a copy of the prescription. For longer trips, set reminders so your refills arrive on time with US shipping from Canada.

Benefits

Brilinta reduces the risk of cardiovascular death, heart attack, and stent thrombosis when used with low-dose aspirin after ACS or PCI. The reversible binding provides potent platelet inhibition with a predictable effect. Tablets are small, portable, and easy to take. Many patients transition to the 60 mg dose after a year for long-term protection.

Browse related options in Heart Health Medications.

Side Effects and Safety

• Bleeding, including nosebleeds, bruising, or gastrointestinal bleeding
• Shortness of breath (dyspnea)
• Headache or dizziness
• Nausea or diarrhea
• Slow heart rate or pauses
• Increased uric acid

Serious risks include major bleeding and, rarely, intracranial hemorrhage. Seek urgent care for signs of severe bleeding. Dyspnea is usually mild to moderate and often occurs early. Use caution before surgeries or dental procedures; prescribers commonly stop ticagrelor several days before elective procedures based on label guidance.

Drug Interactions and Cautions

Strong CYP3A inhibitors (such as ketoconazole and clarithromycin) can raise ticagrelor levels. Strong CYP3A inducers (such as rifampin and carbamazepine) can reduce effectiveness. Limit simvastatin and lovastatin doses when combined, as described in labeling. Ticagrelor is a P-gp substrate; monitor with digoxin. Combining with anticoagulants, NSAIDs, SSRIs, SNRIs, or other antiplatelets can increase bleeding risk. See also background on Clopidogrel 75 Mg. Another antiplatelet example is Persantine®.

What to Expect Over Time

Platelet inhibition begins soon after the loading dose. Maintenance therapy helps reduce recurrent ischemic events over months and years, when taken as prescribed with low-dose aspirin. Mild dyspnea, if it occurs, often appears early and may lessen with time. Safety monitoring typically focuses on bleeding, heart rhythm, and adherence.

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Compare With Alternatives

Several antiplatelets are approved for ACS management. Clopidogrel is widely used and has once-daily dosing. Consider Plavix® if a prescriber recommends a different P2Y12 inhibitor. Another option is Prasugrel, which is used after certain PCI scenarios. Selection depends on clinical factors such as age, stroke history, bleeding risk, and planned surgery. Always follow the treating clinician’s guidance and the official labels.

Pricing and Access

Find Brilinta cost and current Canadian pricing on this page. Compare Brilinta price across strengths and save with US delivery from Canada. You can buy Brilinta online through a secure request once the prescription is verified. Check price and start an order to see available quantities and potential savings. Many patients compare ticagrelor 90 mg price with the 60 mg tablet when planning refills.

Our service supports convenient reorders, transparent pricing, and prompt shipping. If looking for savings without insurance, review multi-pack options and compare tablet strengths before checkout.

Availability and Substitutions

Availability can vary by strength and package size. If a specific product is temporarily unavailable, a prescriber may recommend an appropriate alternative or an equivalent dose form. Do not change antiplatelet therapy without clinical direction.

Patient Suitability and Cost Saving Tips

Brilinta suits many adults after ACS or stent placement when dual antiplatelet therapy is indicated. Patients with prior intracranial hemorrhage, active bleeding, or severe hepatic impairment should avoid ticagrelor. Those with higher bleeding risk need careful monitoring. Discuss options if recurrent dyspnea or bradyarrhythmias occur.

• Ask about moving from 90 mg twice daily to 60 mg twice daily after year one.
• Consider multi-month supplies to reduce per-bottle cost and shipping fees.
• Set refill reminders so your order arrives before you travel.
• Keep aspirin dose within label guidance when used with ticagrelor.

Questions to Ask Your Clinician

• Is Brilinta the right antiplatelet for this specific ACS presentation?
• How long should dual antiplatelet therapy continue after the stent?
• What bleeding signs require urgent evaluation or medication changes?
• Are there reasons to choose clopidogrel or prasugrel instead?
• How many days before elective surgery should ticagrelor be stopped?
• What aspirin dose should accompany ticagrelor long term?
• Do current medicines increase bleeding or change ticagrelor levels?

Authoritative Sources

FDA Prescribing Information

AstraZeneca Brilinta Prescribing Guide

Health Canada Drug Product Database

Ready to get started? Check pricing and request Brilinta with US delivery from Canada. This information is educational and does not replace the advice of a licensed clinician.