Humira® Injection for Autoimmune Conditions

Humira® is a tumor necrosis factor blocker used for several autoimmune diseases. This page explains how the treatment works, how to use it, and what to consider for access with US delivery from Canada. You can also review pricing without insurance to plan your budget.

What Humira Is and How It Works

Adalimumab targets tumor necrosis factor alpha, a key driver of inflammation. By binding TNF, this therapy reduces inflammatory activity in joints, skin, and the gut. It is supplied as an Adalimumab Injection administered under the skin with a pen or prefilled syringe.

CanadianInsulin.com is a prescription referral platform. We verify prescriptions with your prescriber when required, and licensed Canadian pharmacies dispense your order.

Its approved uses vary by condition and age group. Refer to the official prescribing information for full indications, contraindications, and detailed instructions.

Who It’s For

This medicine is prescribed for several immune-mediated conditions in adults and certain pediatric groups. Clinicians may consider it for:

• Rheumatoid Arthritis and psoriatic arthritis
• Ankylosing spondylitis and non-radiographic axial spondyloarthritis
• Plaque psoriasis and hidradenitis suppurativa
• Crohn’s Disease and ulcerative colitis
• Non-infectious uveitis

People with active, serious infections should not use this treatment. Screening for tuberculosis and hepatitis B is recommended before starting. Use caution with demyelinating disorders, moderate to severe heart failure, or a history of certain malignancies. Discuss pregnancy and breastfeeding plans with your healthcare professional.

Dosage and Usage

This treatment is typically injected subcutaneously on a schedule set by your prescriber. Many adult regimens use every-other-week dosing; some may require weekly administration. Always follow the labeled schedule for your condition, and do not change your dose on your own.

The Humira Auto-Injector is designed for at-home use after training. Wash hands, gather supplies, let a refrigerated pen warm to room temperature, and rotate injection sites on the abdomen or thigh. Do not inject into bruised, scarred, or infected skin. Confirm the device window and expiration date before use. If instructions are unclear, review the Medication Guide and talk with your prescriber.

Other biologics in similar formats are listed under Non Insulin Injectables.

Strengths and Forms

Presentations include prefilled pens and prefilled syringes. Availability may vary by supplier and jurisdiction. You may see legacy and citrate-free versions described in listings. A common listing is Humira 40mg 0.8 mL Pen. Your clinician will select a suitable presentation based on indication and patient factors.

Missed Dose and Timing

If you miss a dose, take it when you remember unless it is close to the next scheduled dose. In that case, skip the missed dose and resume the regular schedule. Do not double up. Set reminders, align dosing with a recurring weekly calendar event, and keep a written log to maintain consistency.

Storage and Travel Basics

Refrigerate unopened pens and syringes at 2 to 8°C (36 to 46°F). Do not freeze. Keep products in the original carton to protect from light. Many presentations can be kept at room temperature for a limited time; check the label for the exact allowance and do not return to the refrigerator once kept at room temperature.

For travel, use an insulated carrier with cold packs and keep the medicine away from direct heat. Do not place pens directly on ice. Carry a copy of your prescription and the product leaflet in your hand luggage. If crossing borders, allow extra time for security checks and keep supplies together. Our partners use temperature-controlled handling when required.

Pen Handling and Sharps Disposal

The Adalimumab Pen is single-use. Review the Instructions for Use before the first injection. After use, place the pen or syringe in an FDA-cleared sharps container. When full, follow local rules for household sharps disposal. Never recap needles, and keep all supplies out of reach of children and pets.

• Device prep: inspect the solution and device window
• Injection site: rotate areas to reduce local reactions
• After injection: apply light pressure, avoid rubbing
• Disposal: use a puncture-resistant sharps container

Benefits

This therapy can reduce pain, stiffness, and swelling in inflammatory arthritis. In dermatologic conditions, it may lessen plaques or nodules. In gastrointestinal disease, it can decrease symptoms and help maintain remission. The pen format allows at-home administration after training, which can support treatment continuity.

Side Effects and Safety

• Injection-site reactions: redness, itching, or mild pain
• Upper respiratory symptoms: sinus issues, sore throat, cough
• Headache or fatigue
• Rash or nausea

Serious risks include severe infections, reactivation of tuberculosis or hepatitis B, certain malignancies, heart failure exacerbation, blood disorders, demyelinating disease, and hypersensitivity reactions. Get urgent care for signs of serious infection, trouble breathing, chest pain, unusual bruising, or severe allergic reactions. Review the Medication Guide for the full safety profile.

Drug Interactions and Cautions

Avoid live vaccines during therapy. Using other biologic immunomodulators at the same time is generally not recommended. Concomitant immunosuppressants may increase infection risk. Inform your clinician about all medicines, vitamins, and herbal products. Regular lab and clinical monitoring may be advised based on your condition and co-therapies.

What to Expect Over Time

Response varies by condition and patient factors. Some people notice gradual improvement in mobility, pain, or skin findings with steady use. Others may require dose schedule adjustments per label or a switch to another agent. Keep scheduled visits, track symptoms, and bring your log to appointments. Do not stop therapy without speaking with your prescriber.

Compare With Alternatives

Several targeted therapies can be considered if this option is unsuitable or loses effect. TNF inhibitors such as Enbrel® offer a related mechanism. Interleukin inhibitors like Stelara® act on different inflammatory pathways and may be used in select conditions. For a science-based overview of class differences, see Ustekinumab Vs Adalimumab.

Pricing and Access

Canadian pricing with regulated pharmacy dispensing helps many patients manage specialty drug expenses. You can check Humira Pen Price and compare options by device and quantity, then proceed with your prescription. We also list Adalimumab Price so you can review biosimilar and reference presentations in one place. For potential coupon updates and seasonal offers, visit our Promotions page. Orders are fulfilled by licensed pharmacies and Ships from Canada to US.

Availability and Substitutions

Supply can vary by manufacturer lot, device presentation, or jurisdictional requirements. If an item is unavailable, your prescriber may recommend an approved adalimumab biosimilar or an alternative biologic. To learn how biosimilars are evaluated and approved, explore Biosimilar Drugs.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with moderate to severe inflammatory disease who have not responded sufficiently to conventional treatments. It may not be appropriate for people with uncontrolled infections, certain neurologic conditions, or significant heart failure. Screening and vaccination review are part of the decision process.

• Multi-month supply: discuss longer fills to reduce refill frequency
• Refill reminders: set calendar alerts to avoid missed doses
• Budget planning: review cash price and out-of-pocket limits
• Administration training: request a device demo to improve technique

Questions to Ask Your Clinician

• Which indication and dosing schedule applies to my situation?
• What lab or infection screening is recommended before starting?
• How should I handle dose timing around vaccines or procedures?
• What signs of infection or adverse effects require urgent care?
• Could a biosimilar be appropriate for me now or later?
• How long should I try this treatment before reassessing response?
• What storage and travel steps matter for my specific device?

Authoritative Sources

• AbbVie Humira Prescribing Information
• FDA DailyMed: HUMIRA (search)
• Health Canada Drug Product Database

Ready to proceed? Upload your prescription to CanadianInsulin for prompt, express, cold-chain shipping with US shipping from Canada. This information is educational and does not replace advice from your healthcare professional.