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Micardis Plus® Tablets for Hypertension
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Micardis Plus is a prescription combination blood pressure medicine. It contains telmisartan, an angiotensin II receptor blocker, and hydrochlorothiazide, a thiazide diuretic. This page explains uses, dosing basics, safety, and access with US delivery from Canada without insurance.
What Micardis Plus Is and How It Works
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Micardis Plus combines two antihypertensive agents to help lower elevated blood pressure. Telmisartan blocks angiotensin II at the AT1 receptor, which relaxes blood vessels. Hydrochlorothiazide increases urinary sodium and water excretion, reducing fluid volume. Together, the treatment can provide additive blood pressure reduction compared with either component alone.
The combination is taken once daily. It is intended for adults when monotherapy does not adequately control blood pressure or when a fixed-dose combination is appropriate.
Who It’s For
This medicine is prescribed for adults with primary hypertension. It may be suitable when an angiotensin receptor blocker and a thiazide diuretic are indicated together. Patients with severe kidney impairment, anuria, or known sulfonamide allergy should avoid the diuretic component.
Use during pregnancy can harm the fetus; drugs that act directly on the renin-angiotensin system have a boxed warning regarding fetal toxicity. Do not use with aliskiren in patients with diabetes. In clinical references, the fixed-dose product is also described as telmisartan hydrochlorothiazide micardis plus, reflecting its two active ingredients. Discuss personal risks if you have kidney disease, liver impairment, electrolyte disorders, gout, or a history of angle-closure glaucoma.
If you are being treated for high blood pressure, you can review the condition overview in our Hypertension category for additional context.
Dosage and Usage
Follow your prescriber’s directions and the official label. Typically, the regimen is one oral dose daily, with or without food, taken at the same time each day. Swallow tablets whole with water.
When transitioning from single-agent therapy, clinicians often choose a fixed-dose strength that aligns with current components. Do not split or crush. If salt restriction, diuretics, or dehydration are present, your healthcare provider may replete volume before initiation and monitor closely.
Take a micardis plus tablet exactly as prescribed. Avoid potassium supplements or salt substitutes unless your clinician advises otherwise. Check your blood pressure regularly and record readings to share at follow-up visits.
If you are on other antihypertensives, alcohol, or sedatives, discuss additive blood pressure-lowering effects with your clinician. For background on beta blockers, see our concise Atenolol Guide.
Strengths and Forms
This product is supplied as oral tablets in multiple fixed-dose combinations. Availability can vary.
- Telmisartan 40 mg / Hydrochlorothiazide 12.5 mg
- Telmisartan 80 mg / Hydrochlorothiazide 12.5 mg
- Telmisartan 80 mg / Hydrochlorothiazide 25 mg
The micardis plus generic name is telmisartan and hydrochlorothiazide. Packaging typically includes blister packs or bottles depending on manufacturer and market.
Missed Dose and Timing
If you miss a dose, take it when you remember on the same day. If it is close to your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at once.
Try to dose at a consistent time each day to support adherence and steady blood pressure control.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from moisture and direct light. Keep them in the original container with the label intact and the child-resistant cap secured. Do not store in a bathroom or a hot vehicle.
For travel, carry your medication in hand luggage together with a copy of your prescription or a label matching your ID. Use a daily pill organizer only if it stays dry and protected. Keep out of reach of children and pets.
Benefits
The combination targets two pathways that influence blood pressure: vascular tone and circulating volume. One daily tablet can simplify therapy when both components are needed. This may help reduce pill burden compared with taking the two agents separately.
In addition, angiotensin receptor blockers are often well tolerated relative to some alternatives. Review our Cardiovascular category for related options and clinical topics. For practical tips on lifestyle support, our Blood Pressure Guide offers patient-focused education.
Side Effects and Safety
- Dizziness or lightheadedness, especially when starting
- Fatigue or weakness
- Increased urination
- Back pain or muscle cramps
- Upper respiratory symptoms
- Nausea or abdominal discomfort
- Rash or photosensitivity
Serious but less common risks can include kidney function changes, electrolyte disturbances (low sodium, low or high potassium), severe hypotension, syncope, acute angle-closure glaucoma, or hypersensitivity reactions including angioedema. Seek immediate care for swelling of the face or throat, eye pain with vision changes, or signs of severe dehydration.
If you also use insulin or a sulfonylurea, monitor for hypoglycemia as blood pressure improvement and diuretic effects can change volume status and glucose control. For broader management tips, see our Diabetes and Hypertension article.
Drug Interactions and Cautions
Tell your clinician about all medicines and supplements. Important interactions can occur with lithium, which may reach toxic levels; monitoring is often required. Nonsteroidal anti-inflammatory drugs can reduce diuretic and ARB effects and may worsen kidney function, especially in older adults or those who are volume depleted.
Potassium supplements, potassium-sparing diuretics, or high-potassium diets can increase the risk of hyperkalemia. Alcohol and other antihypertensives can exaggerate blood pressure lowering. Bile acid sequestrants such as cholestyramine may reduce thiazide absorption; doses are often separated. Avoid using aliskiren in people with diabetes. ACE inhibitors like Perindopril may raise the risk of kidney effects and high potassium when combined; combinations require medical oversight. Our brief primer on ACE inhibitor considerations is here: Heart Health and BP.
What to Expect Over Time
Blood pressure reduction may build over days to weeks with consistent dosing. You may feel fine even when your blood pressure is high, so routine monitoring remains important. Bring your home readings to visits to support care decisions.
Adherence is central to long-term control. Use reminders, calendar alerts, or synchronized refill dates to help avoid gaps. If lifestyle changes are under way, discuss any dizziness or fatigue that appears when you stand up, especially during early treatment. For a practical overview of medication and lifestyle roles, read our Atenolol Guide.
Compare With Alternatives
Other fixed-dose ARB and thiazide options include telmisartan with hydrochlorothiazide under different labels and valsartan with hydrochlorothiazide. If your prescriber recommends a comparable pairing, you can review Telmisartan HCT. For a valsartan-based option, see Diovan® HCT. Your clinician will determine the most appropriate agent and strength.
Pricing and Access
Many patients compare pharmacies to understand micardis plus price differences. CanadianInsulin lists current offerings so you can review cash-pay options. We provide transparent product pages with strength selections and quantities before checkout. Savings vary by market and supply.
Orders are processed through licensed Canadian pharmacies with cross-border fulfillment that Ships from Canada to US. Pricing reflects Canadian dispensing when available. Encrypted checkout protects your information. If you are looking for seasonal offers, see our Promotions page.
Availability and Substitutions
Stock can vary by strength and pack size. If a specific tablet is unavailable, your prescriber may recommend an appropriate alternative with the same class or comparable dosing. Some patients ask about the micardis plus generic; the non-branded version is telmisartan and hydrochlorothiazide, subject to availability.
Monotherapy options in the same class include telmisartan itself; see Micardis® for the single-agent ARB. Other ARBs such as Losartan or different ACE inhibitors may also be considered when clinically suitable. Your prescriber will guide any substitution.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults needing two antihypertensive mechanisms in one pill. It is not appropriate in pregnancy, during anuria, or with known sulfonamide hypersensitivity. Extra caution is warranted in kidney impairment, hepatic disease, or electrolyte abnormalities.
To manage expenses, ask your prescriber about multi-month quantities if appropriate, which may reduce per-fill fees. Align refills with routine calendar reminders. If cost remains a concern, compare the ARB alone against the combination when blood pressure is near target, as your clinician advises. For some patients, generic single agents combined separately can also be considered under medical guidance.
Questions to Ask Your Clinician
- Starting dose plan: which strength and why
- Target blood pressure: home and office goals
- Monitoring: kidney function and electrolytes
- Drug interactions: NSAIDs, lithium, or potassium
- Side effects: what to watch for
- Lifestyle: salt intake and hydration
Authoritative Sources
For full prescribing information, review the manufacturer’s labeling on Boehringer Ingelheim’s site, which details indications, dosing, and safety in adults. Access here in a new window: Boehringer Ingelheim official site.
DailyMed provides the FDA-approved label and medication guide, including contraindications and adverse reactions. You can read the latest entry here: FDA DailyMed database.
Health Canada’s Drug Product Database lists authorized products and monographs used nationally. Find reference information here: Health Canada Drug Product Database.
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What is Micardis Plus used for?
It is indicated to treat hypertension in adults when a combination of an angiotensin receptor blocker and a thiazide diuretic is appropriate or when monotherapy is insufficient.
How should I take Micardis Plus?
Take one dose by mouth once daily as directed by your prescriber. It can be taken with or without food. Do not crush or split tablets.
What strengths does Micardis Plus come in?
Common strengths include 40/12.5 mg, 80/12.5 mg, and 80/25 mg telmisartan/hydrochlorothiazide tablets. Availability varies by pharmacy and market.
Can I use Micardis Plus during pregnancy?
No. Drugs that act on the renin-angiotensin system can cause injury and death to the developing fetus. Inform your clinician if you are pregnant or planning pregnancy.
What are common side effects?
Dizziness, increased urination, fatigue, back pain, nausea, and photosensitivity are reported. Serious effects include kidney problems, electrolyte changes, severe hypotension, and rare angioedema.
Does Micardis Plus interact with other medicines?
Yes. Notable interactions include lithium, NSAIDs, potassium supplements or sparing diuretics, aliskiren in diabetics, and other blood pressure medicines. Always inform your clinician.
How should I store Micardis Plus?
Store at room temperature in a dry place, protected from light and moisture. Keep in the original, labeled container and out of reach of children.
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